Reactome | klhl11 [cytosol]

klhl11 [cytosol]

Stable Identifier

R-XTR-8851653

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

KLHL11, A0A803J664

Locations in the PathwayBrowser

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Metabolism of proteins (Xenopus tropicalis)

- Post-translational protein modification (Xenopus tropicalis)
  - Neddylation (Xenopus tropicalis)
    - AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Xenopus tropicalis)
      - NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Xenopus tropicalis)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        RBX1:CUL3:BTB [cytosol] (Xenopus tropicalis)
        
        BTB proteins [cytosol] (Xenopus tropicalis)
        
        klhl11 [cytosol] (Xenopus tropicalis)
      - NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Xenopus tropicalis)
        
        NEDD8-CUL3:RBX1:BTB [cytosol] (Xenopus tropicalis)
        
        BTB proteins [cytosol] (Xenopus tropicalis)
        
        klhl11 [cytosol] (Xenopus tropicalis)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Xenopus tropicalis)
        
        CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        RBX1:CUL3:BTB [cytosol] (Xenopus tropicalis)
        
        BTB proteins [cytosol] (Xenopus tropicalis)
        
        klhl11 [cytosol] (Xenopus tropicalis)
      - CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        RBX1:CUL3:BTB [cytosol] (Xenopus tropicalis)
        
        BTB proteins [cytosol] (Xenopus tropicalis)
        
        klhl11 [cytosol] (Xenopus tropicalis)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Xenopus tropicalis)
        
        CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        RBX1:CUL3:BTB [cytosol] (Xenopus tropicalis)
        
        BTB proteins [cytosol] (Xenopus tropicalis)
        
        klhl11 [cytosol] (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        RBX1:CUL3:BTB [cytosol] (Xenopus tropicalis)
        
        BTB proteins [cytosol] (Xenopus tropicalis)
        
        klhl11 [cytosol] (Xenopus tropicalis)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Xenopus tropicalis)
        
        RBX1:CUL3:BTB [cytosol] (Xenopus tropicalis)
        
        BTB proteins [cytosol] (Xenopus tropicalis)
        
        klhl11 [cytosol] (Xenopus tropicalis)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Xenopus tropicalis)
        
        NEDD8-CUL3:RBX1:BTB [cytosol] (Xenopus tropicalis)
        
        BTB proteins [cytosol] (Xenopus tropicalis)
        
        klhl11 [cytosol] (Xenopus tropicalis)
    - NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Xenopus tropicalis)
      - CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        RBX1:CUL3:BTB [cytosol] (Xenopus tropicalis)
        
        BTB proteins [cytosol] (Xenopus tropicalis)
        
        klhl11 [cytosol] (Xenopus tropicalis)
      - NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Xenopus tropicalis)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        RBX1:CUL3:BTB [cytosol] (Xenopus tropicalis)
        
        BTB proteins [cytosol] (Xenopus tropicalis)
        
        klhl11 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A803J664

Gene Names

klhl11

Reference Genes

BioGPS Gene:100491061 klhl11

ENSEMBL:ENSXETG00000042941

KEGG:xtr:100491061 klhl11

Monarch:100491061 klhl11

NCBI Gene:100491061 klhl11

UCSC:A0A803J664 klhl11

Reference Transcript

RefSeq:XM_002939032.5 klhl11

Other Identifiers

100491061

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)

as a member of

BTB proteins [cytosol] (Xenopus tropicalis)

Inferred From

KLHL11 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_002939078.1

ENSEMBL

ENSXETT00000113953, ENSXETT00000111048, ENSXETP00000116357, ENSXETP00000103324

Xenbase

XB-GENE-992466

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