Reactome | UniProt:P01375 TNF

UniProt:P01375 TNF

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

TNFA_HUMAN, O43647, Q9P1Q2, Q9UIV3

List of interactors in Reactome

Interactors (23)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
Q13546	4	K48polyUb-K571,K604,K627-RIPK1 [cytosol] (R-HSA-9796639) RIPK1 [cytosol] (R-HSA-168651) RIPK1 [plasma membrane] (R-HSA-937073) RIPK1(1-324) [cytosol] (R-HSA-5212664)	0.877	17
Q12933	1	TRAF2 [cytosol] (R-HSA-66370)	0.837	13
Q13490	3	BIRC2 [cytosol] (R-HSA-50847) BIRC2(1-372) [cytosol] (R-HSA-202913) BIRC2(373-618) [cytosol] (R-HSA-202931)	0.837	9
P20333	1	TNFRSF1B [plasma membrane] (R-HSA-5661484)	0.792	5
Q15628	1	TRADD [cytosol] (R-HSA-66376)	0.788	11
Q9H0F6	1	SHARPIN [cytosol] (R-HSA-5212666)	0.788	11
Q9Y6K9	3	IKBKG [cytosol] (R-HSA-168108) IKBKG [nucleoplasm] (R-HSA-4755413) monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449)	0.744	7
P01375	4	TNF(1-233) [plasma membrane] (R-HSA-66220) TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(52-76) [extracellular region] (R-HSA-8863375) TNF(77-233) [extracellular region] (R-HSA-976821)	0.73	3
P21580	1	TNFAIP3 [cytosol] (R-HSA-688989)	0.643	6
Q16623	1	STX1A [plasma membrane] (R-HSA-449128)	0.601	4
Q60855	3	Ripk1 [cytosol] (R-MMU-168651) Ripk1 [cytosol] (R-MMU-5212664) Ripk1 [cytosol] (R-MMU-9796639)	0.576	4
29108	12	Ca2+ [cytosol] (R-ALL-74016) Ca2+ [endoplasmic reticulum lumen] (R-ALL-111875) Ca2+ [endoplasmic reticulum-Golgi intermediate compartment] (R-ALL-9706979) Ca2+ [extracellular region] (R-ALL-74112) Ca2+ [Golgi lumen] (R-ALL-167012) Ca2+ [lysosomal lumen] (R-ALL-1606834) Ca2+ [mitochondrial intermembrane space] (R-ALL-8949232) Ca2+ [mitochondrial matrix] (R-ALL-8949220) Ca2+ [nucleoplasm] (R-ALL-29496) Ca2+ [plasma membrane] (R-ALL-140648) Ca2+ [platelet dense tubular network lumen] (R-ALL-139827) Ca2+ [sarcoplasmic reticulum lumen] (R-ALL-2855229)	0.558	5
O15552	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
P05067	12	APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-713) [extracellular region] (R-HSA-879340) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325)	0.556	3
Q16585	1	SGCB [endoplasmic reticulum membrane] (R-HSA-9913185)	0.556	3
Q8IUN9	1	CLEC10A [plasma membrane] (R-HSA-1472863)	0.556	3
Q96BA8	7	CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139)	0.556	3
Q9HC36	1	RNMTL1 [mitochondrial matrix] (R-HSA-6793067)	0.556	3
Q14118	21	3S-Matriglycan-DAG1 [Golgi lumen] (R-HSA-9940731) Core M1,2,3-DAG1 [Golgi lumen] (R-HSA-8932424) Core M1,3-DAG1 [Golgi lumen] (R-HSA-5617087) Core M3-DAG1 [Golgi lumen] (R-HSA-9940750) DAG1 [endoplasmic reticulum membrane] (R-HSA-9913254) DAG1(30-653) [cytosol] (R-HSA-5615641) DAG1(30-653) [endoplasmic reticulum lumen] (R-HSA-8931890) DAG1(30-653) [extracellular region] (R-HSA-2328152) DAG1(654-895) [endoplasmic reticulum membrane] (R-HSA-9913257) DAG1(654-895) [Golgi membrane] (R-HSA-9913184) GalNAc-GlcNAc-Man-DAG1 [endoplasmic reticulum lumen] (R-HSA-8931656) GalNAc-GlcNAc-Man6P-DAG1 [endoplasmic reticulum lumen] (R-HSA-8931659) GlcA-Xyl-RboP-RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen] (R-HSA-9940727) GlcNAc-Man-DAG1 [endoplasmic reticulum lumen] (R-HSA-8931673) Man-DAG1 [endoplasmic reticulum lumen] (R-HSA-5615647) Man-DAG1 [Golgi lumen] (R-HSA-8931888) Matriglycan-DAG1 [Golgi lumen] (R-HSA-9940706) RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen] (R-HSA-9940763) RboP-RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen] (R-HSA-9940668) Xyl-GlcA-Xyl-RboP-RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen] (R-HSA-9940697) Xyl-RboP-RboP-GalNAc-GlcNAc-Man6P-DAG1 [Golgi lumen] (R-HSA-9940723)	0.527	2
O88351	2	Ikbkb [cytosol] (R-MMU-168114) phospho-Ikbkb [cytosol] (R-MMU-202506)	0.499	3
O89110	1	Casp8 [cytosol] (R-MMU-57031)	0.499	2
Q3U0V2	1	Tradd [cytosol] (R-MMU-66376)	0.499	2
Q60769	1	Tnfaip3 [cytosol] (R-MMU-688989)	0.499	2

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