Reactome | UniProt:P0DTC2 S

UniProt:P0DTC2 S

Type

Interactor (Protein)

Species

Severe acute respiratory syndrome coronavirus 2

Synonyms

SPIKE_SARS2

List of interactors in Reactome

Interactors (23)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
Q9BYF1	4	ACE2 [endocytic vesicle membrane] (R-HSA-9698958) ACE2 [endoplasmic reticulum lumen] (R-HSA-9683474) glycosylated-ACE2 [endocytic vesicle membrane] (R-HSA-9686721) glycosylated-ACE2 [plasma membrane] (R-HSA-9683480)	0.997	242
P0DTC2	10	14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9766369) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) S(686-815) [plasma membrane] (R-COV-9770188) S1 [plasma membrane] (R-COV-9769950) Spike S2' Fragment [plasma membrane] (R-COV-9770189)	0.986	60
P09958	3	FURIN [Golgi membrane] (R-HSA-157049) FURIN [macropinosome membrane] (R-HSA-9837714) FURIN [plasma membrane] (R-HSA-2159856)	0.854	5
Q9NNX6	1	CD209 [plasma membrane] (R-HSA-2079928)	0.848	11
P11021	2	HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [extracellular region] (R-HSA-351322)	0.746	8
Q96D42	1	HAVCR1 [plasma membrane] (R-HSA-5660386)	0.667	7
P30530	1	AXL [plasma membrane] (R-HSA-197705)	0.655	9
P35613	2	BSG [Golgi membrane] (R-HSA-204478) BSG [plasma membrane] (R-HSA-197673)	0.652	7
O14786	1	NRP1 [plasma membrane] (R-HSA-3008773)	0.639	9
P35579	1	MYH9 [cytosol] (R-HSA-419173)	0.636	8
17306	2	Mal [cytosol] (R-ALL-868706) Mal [extracellular region] (R-ALL-188986)	0.623	3
50385	1	hemin [cytosol] (R-ALL-421489)	0.59	2
P14635	2	CCNB1 [cytosol] (R-HSA-157451) CCNB1 [nucleoplasm] (R-HSA-68901)	0.59	2
16113	12	CHOL [cytosol] (R-ALL-176478) CHOL [endoplasmic reticulum lumen] (R-ALL-174672) CHOL [endoplasmic reticulum membrane] (R-ALL-193384) CHOL [extracellular region] (R-ALL-171149) CHOL [lipid droplet] (R-ALL-163586) CHOL [lysosomal lumen] (R-ALL-8848047) CHOL [mitochondrial inner membrane] (R-ALL-193156) CHOL [mitochondrial matrix] (R-ALL-193840) CHOL [mitochondrial outer membrane] (R-ALL-8951853) CHOL [plasma membrane] (R-ALL-171095) CHOL [smooth endoplasmic reticulum] (R-ALL-8866305) CHOL [transport vesicle membrane] (R-ALL-216762)	0.558	5
16412	2	LPS [extracellular region] (R-ALL-166005) LPS [peptidoglycan-based cell wall] (R-ALL-6803081)	0.558	3
17012	1	Neu5Ac [Golgi lumen] (R-ALL-975925)	0.558	2
P00533	2	EGFR [plasma membrane] (R-HSA-179837) EGFRvIII [plasma membrane] (R-HSA-1214162)	0.537	4
P01130	2	LDLR [endosome membrane] (R-HSA-171127) LDLR [plasma membrane] (R-HSA-171053)	0.537	4
P08670	7	VIM [cytosol] (R-HSA-201600) VIM(2-259) [cytosol] (R-HSA-350323) VIM(2-429) [cytosol] (R-HSA-350317) VIM(2-85) [cytosol] (R-HSA-350264) VIM(260-466) [cytosol] (R-HSA-350314) VIM(430-466) [cytosol] (R-HSA-350316) VIM(86-466) [cytosol] (R-HSA-350294)	0.524	4
17351	1	LINA [endoplasmic reticulum lumen] (R-ALL-2046044)	0.522	2
P26038	1	MSN [cytosol] (R-HSA-437350)	0.499	20
Q15436	2	p-S738,T744 SEC23A [cytosol] (R-HSA-5685740) SEC23A [cytosol] (R-HSA-203972)	0.499	20
P15311	1	EZR [cytosol] (R-HSA-9020826)	0.483	10

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