Reactome | UniProt:P10636-8 MAPT

UniProt:P10636-8 MAPT

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

TAU_HUMAN, P18518, Q14799, Q15549, Q15550, Q15551, Q1RMF6, Q53YB1, Q5CZI7, Q5XWF0, Q6QT54, Q9UDJ3, Q9UMH0, Q9UQ96

List of interactors in Reactome

Interactors (133)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P08238	1	HSP90AB1 [cytosol] (R-HSA-419617)	0.876	18
P49841	2	GSK3B [cytosol] (R-HSA-2997551) GSK3B [nucleoplasm] (R-HSA-2022823)	0.797	12
P10636	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521)	0.771	6
P07355	4	ANXA2 [cytosol] (R-HSA-5263667) ANXA2 [extracellular region] (R-HSA-6806242) p-S26-ANXA2 [cytosol] (R-HSA-9865163) p-Y24,S26-ANXA2 [cytosol] (R-HSA-9865224)	0.723	10
P07237	2	HC53,56-P4HB [endoplasmic reticulum lumen] (R-HSA-3341287) P4HB [endoplasmic reticulum lumen] (R-HSA-174692)	0.713	6
Q13200	1	PSMD2 [cytosol] (R-HSA-68796)	0.712	7
Q14203	1	DCTN1 [cytosol] (R-HSA-535580)	0.704	9
Q13451	1	FKBP5 [cytosol] (R-HSA-5618096)	0.698	8
P37840	3	p-S129-SNCA [cytosol] (R-HSA-9836432) SNCA [cytosol] (R-HSA-5658500) Ub-SNCA [cytosol] (R-HSA-5660754)	0.681	12
Q5S007	1	LRRK2 [cytosol] (R-HSA-5661173)	0.676	9
P35998	1	PSMC2 [cytosol] (R-HSA-68771)	0.671	10
O00231	1	PSMD11 [cytosol] (R-HSA-68790)	0.643	6
O43242	1	PSMD3 [cytosol] (R-HSA-68798)	0.643	6
P11021	2	HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [extracellular region] (R-HSA-351322)	0.643	7
P19338	2	NCL [nucleoplasm] (R-HSA-6791213) NCL [plasma membrane] (R-HSA-9836466)	0.643	5
P22626	1	HNRNPA2B1 [extracellular exosome] (R-HSA-8950304)	0.643	5
P26641	1	EEF1G [cytosol] (R-HSA-156925)	0.643	5
P46821	1	MAP1B(2-2206) [cytosol] (R-HSA-9836954)	0.643	5
P60709	2	ACTB [cytosol] (R-HSA-201861) ACTB [nucleoplasm] (R-HSA-3321990)	0.643	5
P62191	1	PSMC1 [cytosol] (R-HSA-68768)	0.643	5
Q02790	2	FKBP4 [cytosol] (R-HSA-5618108) FKBP4 [nucleoplasm] (R-HSA-5324621)	0.629	7
P14625	1	HSP90B1 [endoplasmic reticulum lumen] (R-HSA-981545)	0.623	5
P05067	12	APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-713) [extracellular region] (R-HSA-879340) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325)	0.59	4
P49840	2	GSK3A [cytosol] (R-HSA-198326) p-Y279-GSK3A [cytosol] (R-HSA-9635490)	0.59	2
P06241	3	FYN [cytosol] (R-HSA-200917) p-Y420-FYN [cytosol] (R-HSA-391821) p-Y531-FYN [cytosol] (R-HSA-391819)	0.581	9
P00338	2	LDHA [cytosol] (R-HSA-70502) PolyUb-LDHA [cytosol] (R-HSA-9861549)	0.569	5
P07900	1	HSP90AA1 [cytosol] (R-HSA-192864)	0.569	11
P11142	5	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [plasma membrane] (R-HSA-936508) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.569	11
P11940	1	PABPC1 [cytosol] (R-HSA-156803)	0.569	11
P12814	1	ACTN1 [cytosol] (R-HSA-354096)	0.569	6
P13639	7	ADP-ribo-EEF2 [cytosol] (R-HSA-5334764) aminocarboxypropyl EEF2 [cytosol] (R-HSA-5358478) diphthine EEF2 [cytosol] (R-HSA-5358501) EEF2 [cytosol] (R-HSA-156901) Me-diphthine EEF2 [cytosol] (R-HSA-5367025) Me3K525-EEF2 [cytosol] (R-HSA-8932237) nascent EEF2 [cytosol] (R-HSA-5358472)	0.569	8
P23528	2	CFL1 [cytosol] (R-HSA-350751) p-S3-CFL1 [cytosol] (R-HSA-399813)	0.569	10
P31689	2	DNAJA1 [cytosol] (R-HSA-3371544) SOH-C149,C150-DNAJA1 [cytosol] (R-HSA-9857072)	0.569	8
P31948	1	STIP1 [cytosol] (R-HSA-443857)	0.569	8
P46781	1	RPS9 [nucleoplasm] (R-HSA-6790663)	0.569	7
P51149	1	RAB7A [phagocytic vesicle membrane] (R-HSA-9636586)	0.569	11
P61247	1	RPS3A [nucleoplasm] (R-HSA-6791182)	0.569	9
P62195	1	PSMC5 [cytosol] (R-HSA-68780)	0.569	9
P62258	1	YWHAE [cytosol] (R-HSA-194368)	0.569	11
P62263	1	RPS14 [nucleoplasm] (R-HSA-6790669)	0.569	6
P63104	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.569	10
P67809	4	p-S32,S36-YBX1 [cytosol] (R-HSA-9736837) p-S32,S36-YBX1 [nucleoplasm] (R-HSA-9733227) YBX1 [cytosol] (R-HSA-9736840) YBX1 [extracellular region] (R-HSA-9017791)	0.569	11
P68104	4	EEF1A1 [cytosol] (R-HSA-156905) EEF1A1 [lysosomal membrane] (R-HSA-9626022) Me3K318-EEF1A1 [cytosol] (R-HSA-8932419) Me3K79-EEF1A1 [cytosol] (R-HSA-8932212)	0.569	8
Q13813	3	SPTAN1 [cytosol] (R-HSA-201601) SPTAN1(1-1185) [cytosol] (R-HSA-202944) SPTAN1(1186-2472) [cytosol] (R-HSA-202964)	0.569	10
Q14974	2	KPNB1 [cytosol] (R-HSA-180733) KPNB1 [nucleoplasm] (R-HSA-180714)	0.569	11
Q96CW1	1	AP2M1 [plasma membrane] (R-HSA-167585)	0.569	9
Q9Y230	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.569	8
Q9Y265	1	RUVBL1 [nucleoplasm] (R-HSA-418323)	0.569	10
Q9Y266	2	NUDC [nucleoplasm] (R-HSA-156716) p-S274,S326-NUDC [cytosol] (R-HSA-156702)	0.569	8
P08133	1	ANXA6 [cytosol] (R-HSA-5263641)	0.564	5
P07437	1	TUBB [cytosol] (R-HSA-9020816)	0.547	4
O00232	1	PSMD12 [cytosol] (R-HSA-68792)	0.527	5
O00487	1	PSMD14 [cytosol] (R-HSA-68722)	0.527	4
O14818	1	PSMA7 [cytosol] (R-HSA-68736)	0.527	4
O14979	1	HNRNPDL [cytosol] (R-HSA-8950323)	0.527	5
O43684	1	BUB3 [cytosol] (R-HSA-141416)	0.527	4
O43776	1	NARS [cytosol] (R-HSA-379625)	0.527	4
O75396	3	SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [Golgi membrane] (R-HSA-6810993)	0.527	4
P05388	1	RPLP0 [cytosol] (R-HSA-72396)	0.527	5
P05455	1	SSB [nucleoplasm] (R-HSA-58418)	0.527	4
P06730	1	EIF4E [cytosol] (R-HSA-72578)	0.527	4
P06733	1	ENO1 [cytosol] (R-HSA-71437)	0.527	4
P06748	6	monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039) NPM1 [cytosol] (R-HSA-3008211) NPM1 [granular component] (R-HSA-9017702) NPM1 [nucleoplasm] (R-HSA-606320) p-S4-NPM1 [cytosol] (R-HSA-6801679) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056)	0.527	6
P07910	2	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543)	0.527	4
P10809	1	HSPD1 [mitochondrial matrix] (R-HSA-1299448)	0.527	4
P15880	2	Me2aR-RPS2 [cytosol] (R-HSA-8879138) RPS2 [cytosol] (R-HSA-72347)	0.527	6
P16949	1	STMN1 [cytosol] (R-HSA-9612290)	0.527	4
P17677	2	GAP43 [plasma membrane] (R-HSA-452888) PALM-C3,4-GAP43 [plasma membrane] (R-HSA-8933482)	0.527	4
P17844	4	DDX5 [cytosol] (R-HSA-9682643) DDX5 [nucleoplasm] (R-HSA-3900136) monoSUMO1-K53-DDX5 [nucleoplasm] (R-HSA-3900041) polySUMO2-K53-DDX5 [nucleoplasm] (R-HSA-3900186)	0.527	4
P17980	1	PSMC3 [cytosol] (R-HSA-68774)	0.527	5
P17987	1	TCP1 [cytosol] (R-HSA-390448)	0.527	4
P23246	3	p-Y-SFPQ [nucleoplasm] (R-HSA-8849461) SFPQ [cytosol] (R-HSA-9635505) SFPQ [nucleoplasm] (R-HSA-3900138)	0.527	5
P25786	1	PSMA1 [cytosol] (R-HSA-68724)	0.527	6
P25787	1	PSMA2 [cytosol] (R-HSA-68726)	0.527	5
P26599	1	PTBP1 [nucleoplasm] (R-HSA-71923)	0.527	4
P27695	1	APEX1 [nucleoplasm] (R-HSA-50119)	0.527	5
P27797	4	CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [lumenal side of endoplasmic reticulum membrane] (R-HSA-985502) CALR [phagocytic vesicle membrane] (R-HSA-1236879)	0.527	4
P28074	2	pro-PSMB5 [cytosol] (R-HSA-9908135) PSMB5(1-59) [cytosol] (R-HSA-9908134)	0.527	4
P29966	2	MARCKS [plasma membrane] (R-HSA-399985) p-4S-MARCKS [plasma membrane] (R-HSA-399989)	0.527	5
P31946	1	YWHAB [cytosol] (R-HSA-48888)	0.527	4
P35813	2	PPM1A [cytosol] (R-HSA-380928) PPM1A [nucleoplasm] (R-HSA-205813)	0.527	4
P38646	2	HSPA9 [mitochondrial matrix] (R-HSA-8878802) HSPA9(1-679) [mitochondrial intermembrane space] (R-HSA-1267968)	0.527	5
P40429	2	p-RPL13A [cytosol] (R-HSA-156829) RPL13A [cytosol] (R-HSA-72412)	0.527	6
P43686	1	PSMC4 [cytosol] (R-HSA-68777)	0.527	4
P46459	1	NSF [cytosol] (R-HSA-264471)	0.527	4
P46776	2	3OHH39-RPL27A [nucleoplasm] (R-HSA-9630970) RPL27A [nucleoplasm] (R-HSA-9630984)	0.527	5
P46782	1	RPS5 [nucleoplasm] (R-HSA-6791188)	0.527	5
P49327	2	FASN [cytosol] (R-HSA-54659) FASN [cytosol] (R-HSA-199233)	0.527	4
P49411	1	TUFM [mitochondrial outer membrane] (R-HSA-9754777)	0.527	4
P49588	1	AARS [cytosol] (R-HSA-379666)	0.527	4
P49721	1	PSMB2 [cytosol] (R-HSA-68744)	0.527	5
P52272	1	HNRNPM [nucleoplasm] (R-HSA-71949)	0.527	4
P52907	1	CAPZA1 [cytosol] (R-HSA-879363)	0.527	4
P55036	1	PSMD4 [cytosol] (R-HSA-68800)	0.527	5
P61978	2	HNRNPK [nucleoplasm] (R-HSA-71945) polySUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.527	6
P62081	1	RPS7 [nucleoplasm] (R-HSA-6790635)	0.527	6
P62241	1	RPS8 [nucleoplasm] (R-HSA-6791203)	0.527	4
P62277	1	RPS13 [nucleoplasm] (R-HSA-6791198)	0.527	6
P62280	1	RPS11 [nucleoplasm] (R-HSA-6791212)	0.527	7
P62316	1	SNRPD2 [cytosol] (R-HSA-191810)	0.527	4
P62753	4	3OHR147-RPS6 [cytosol] (R-HSA-9629876) p-5S-RPS6 [cytosol] (R-HSA-165727) RPS6 [cytosol] (R-HSA-72381) RPS6 [nucleoplasm] (R-HSA-6790606)	0.527	6
P62847	1	RPS24 [nucleoplasm] (R-HSA-6791186)	0.527	7
P62857	1	RPS28 [nucleoplasm] (R-HSA-6791202)	0.527	4
P62917	2	3OHH216-RPL8 [nucleoplasm] (R-HSA-9630976) RPL8 [nucleoplasm] (R-HSA-9630985)	0.527	6
P62979	3	RPS27A [cytosol] (R-HSA-8853524) RPS27A(1-76) [cytosol] (R-HSA-939205) RPS27A(77-156) [cytosol] (R-HSA-72363)	0.527	6
P63244	1	RACK1 [cytosol] (R-HSA-5626956)	0.527	6
P84103	1	SRSF3 [nucleoplasm] (R-HSA-72035)	0.527	4
P84243	2	H3F3A [nucleoplasm] (R-HSA-212295) H3R17me2a [nucleoplasm] (R-HSA-9822613)	0.527	5
Q00535	3	CDK5 [cytosol] (R-HSA-180064) CDK5 [nucleoplasm] (R-HSA-8863586) p-Y15-CDK5 [cytosol] (R-HSA-399809)	0.527	4
Q00839	1	HNRNPU [nucleoplasm] (R-HSA-71953)	0.527	5
Q04637	2	EIF4G1 [cytosol] (R-HSA-72584) p-S1108,S1148,S1192-EIF4G1 [cytosol] (R-HSA-165762)	0.527	4
Q04837	1	SSBP1 [mitochondrial matrix] (R-HSA-1592217)	0.527	4
Q06323	1	PSME1 [cytosol] (R-HSA-68812)	0.527	5
Q06830	2	p-T90-PRDX1 [cytosol] (R-HSA-8868564) PRDX1 [cytosol] (R-HSA-3341270)	0.527	4
Q07666	3	KHDRBS1 [nucleoplasm] (R-HSA-8848941) p-Y435,Y440,Y443-KHDRBS1 [cytosol] (R-HSA-8848995) p-Y435,Y440,Y443-KHDRBS1 [nucleoplasm] (R-HSA-8848970)	0.527	5
Q08211	3	DHX9 [cytosol] (R-HSA-847700) DHX9 [nucleoplasm] (R-HSA-53517) p-DHX9 [cytosol] (R-HSA-9836168)	0.527	6
Q12906	3	ILF3 [cytosol] (R-HSA-450564) ILF3 [nucleoplasm] (R-HSA-9760401) p-T188,T315-ILF3 [cytosol] (R-HSA-9836381)	0.527	4
Q13177	9	K48polyUb-p-T402-PAK-2p43 [cytosol] (R-HSA-3095873) p-5S-PAK2 [cytosol] (R-HSA-211609) p-5S-PAK2(2-212) [cytosol] (R-HSA-211588) p-S141,T402-PAK2 [cytosol] (R-HSA-399824) p-T402-PAK2(213-524) [cytosol] (R-HSA-211654) p-T402-PAK2(213-524) [nucleoplasm] (R-HSA-211709) PAK2 [cytosol] (R-HSA-211604) PAK2(1-524) [plasma membrane] (R-HSA-164946) PAK2(213-524) [cytosol] (R-HSA-211653)	0.527	4
Q13263	1	TRIM28 [nucleoplasm] (R-HSA-974998)	0.527	4
Q15149	3	PLEC [cytosol] (R-HSA-201575) PLEC(1-2395) [cytosol] (R-HSA-350638) PLEC(2396-4684) [cytosol] (R-HSA-350618)	0.527	5
Q92841	2	DDX17 [nucleoplasm] (R-HSA-3900090) monoSUMO1-K50-DDX17 [nucleoplasm] (R-HSA-3900104)	0.527	4
Q92900	2	p-4S-UPF1 [cytosol] (R-HSA-927856) UPF1 [cytosol] (R-HSA-927734)	0.527	3
Q92945	3	KSRP [cytosol] (R-HSA-450485) p-S193-KHSRP [cytosol] (R-HSA-450505) p-T692-KHSRP [cytosol] (R-HSA-451177)	0.527	4
Q99436	2	pro-PSMB7 [cytosol] (R-HSA-9908145) PSMB7(1-43) [cytosol] (R-HSA-9908129)	0.527	4
Q99460	1	PSMD1 [cytosol] (R-HSA-68786)	0.527	4
Q9HC35	1	EML4 [cytosol] (R-HSA-9647741)	0.527	4
Q9UNM6	1	PSMD13 [cytosol] (R-HSA-68794)	0.527	5
Q9Y2W1	1	THRAP3 [nucleoplasm] (R-HSA-8932115)	0.527	6
Q9Y5B9	1	SUPT16H [nucleoplasm] (R-HSA-112415)	0.527	6
P27448	1	MARK3 [cytosol] (R-HSA-5672591)	0.483	4
Q14155	1	ARHGEF7 [cytosol] (R-HSA-430346)	0.483	3
Q9Y2Z0	1	SUGT1 [cytosol] (R-HSA-874107)	0.483	4
P61764	1	STXBP1 [plasma membrane] (R-HSA-2980862)	0.463	10

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