Reactome | UniProt:P27348 YWHAQ

UniProt:P27348 YWHAQ

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

1433T_HUMAN, D6W4Z5, Q567U5, Q5TZU8, Q9UP48

List of interactors in Reactome

Interactors (80)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P04049	3	hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) RAF1 [cytosol] (R-HSA-167205)	0.932	25
P62258	1	YWHAE [cytosol] (R-HSA-194368)	0.916	14
P46937	8	p-5S-YAP1 [cytosol] (R-HSA-2028554) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-Y407-YAP1 [cytosol] (R-HSA-9865208) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322)	0.915	10
P15056	3	BRAF [cytosol] (R-HSA-167224) hyperphosphorylated BRAF [plasma membrane] (R-HSA-5675199) p-S446,T599,S602,S729 BRAF [plasma membrane] (R-HSA-5672679)	0.908	12
Q9UBF8	1	PI4KB [cytosol] (R-HSA-1604615)	0.905	8
P27448	1	MARK3 [cytosol] (R-HSA-5672591)	0.894	10
P40818	2	p-T945-USP8 [cytosol] (R-HSA-1358714) USP8 [cytosol] (R-HSA-917720)	0.867	9
Q5S007	1	LRRK2 [cytosol] (R-HSA-5661173)	0.862	10
P49815	3	p-S939,S1130,T1462-TSC2 [cytosol] (R-HSA-165164) p-S939,T1462-TSC2 [cytosol] (R-HSA-199484) TSC2 [cytosol] (R-HSA-2980548)	0.86	7
Q02241	2	KIF23 [nucleoplasm] (R-HSA-156709) p-S911,S912-KIF23 [nucleoplasm] (R-HSA-156695)	0.859	8
Q92934	4	BAD [cytosol] (R-HSA-50662) BAD [mitochondrial outer membrane] (R-HSA-114242) p-S91-BAD [cytosol] (R-HSA-217297) p-S99-BAD [cytosol] (R-HSA-198335)	0.857	8
P00533	2	EGFR [plasma membrane] (R-HSA-179837) EGFRvIII [plasma membrane] (R-HSA-1214162)	0.854	7
P31946	1	YWHAB [cytosol] (R-HSA-48888)	0.851	8
P61981	1	YWHAG [cytosol] (R-HSA-380312)	0.851	11
P26045	2	PTPN3 [cytosol] (R-HSA-8867650) PTPN3 [plasma membrane] (R-HSA-5490317)	0.848	7
P63104	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.848	12
P56524	3	HDAC4 [nucleoplasm] (R-HSA-351581) monoSUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) polySUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029)	0.827	7
P22681	3	CBL [cytosol] (R-HSA-112199) p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-912656) PolyUb,p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-8848826)	0.812	7
Q6PKG0	1	LARP1 [cytosol] (R-HSA-9760421)	0.776	6
O75044	1	SRGAP2 [cytosol] (R-HSA-195131)	0.774	5
Q9UQC2	1	GAB2 [cytosol] (R-HSA-508239)	0.774	7
Q9P0V3	1	SH3BP4 [cytosol] (R-HSA-8866227)	0.763	6
Q9Y4H2	1	IRS2 [cytosol] (R-HSA-57528)	0.763	6
Q86TI0	2	p-S237-TBC1D1 [cytosol] (R-HSA-1454673) TBC1D1 [cytoplasmic vesicle membrane] (R-HSA-1454718)	0.745	7
Q9UQB8	1	BAIAP2 [cytosol] (R-HSA-442574)	0.745	7
Q9BZ23	1	PANK2(111-570) [mitochondrial intermembrane space] (R-HSA-196803)	0.744	4
P30305	4	CDC25B [cytosol] (R-HSA-157412) CDC25B [nucleoplasm] (R-HSA-69734) p-S-CDC25B [nucleoplasm] (R-HSA-9929936) p-S50,T69,S160,S321,S470-CDC25B [cytosol] (R-HSA-8863644)	0.725	4
P36507	4	MAP2K2 [cytosol] (R-HSA-59504) MAP2K2(1-10) [cytosol] (R-HSA-5211334) MAP2K2(11-400) [cytosol] (R-HSA-5211337) p-S,T-MAP2K2 [cytosol] (R-HSA-109848)	0.725	5
Q02750	4	MAP2K1 [cytosol] (R-HSA-59502) MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1(9-393) [cytosol] (R-HSA-5211353) p-S218,S222-MAP2K1 [cytosol] (R-HSA-109837)	0.725	5
Q5SQI0	1	ATAT [cytosol] (R-HSA-5618184)	0.725	4
Q9GZV5	3	p-S89-WWTR1 [cytosol] (R-HSA-2028665) WWTR1 [cytosol] (R-HSA-1629773) WWTR1 [nucleoplasm] (R-HSA-1629775)	0.725	4
Q9H0H5	1	RACGAP1 [cytosol] (R-HSA-195122)	0.725	4
P46527	5	CDKN1B [cytosol] (R-HSA-198622) CDKN1B [nucleoplasm] (R-HSA-182563) p-S10 CDKN1B [cytosol] (R-HSA-9632829) p-S10 CDKN1B [nucleoplasm] (R-HSA-9632832) p-Y88-CDKN1B [cytosol] (R-HSA-8848438)	0.724	5
A7KAX9	1	ARHGAP32 [cytosol] (R-HSA-195134)	0.706	5
O43166	1	SPAR [cytosol] (R-HSA-6794278)	0.706	4
Q13009	1	TIAM1 [cytosol] (R-HSA-195013)	0.706	4
Q9NYA4	1	MTMR4 [early endosome membrane] (R-HSA-2187404)	0.706	5
P10636	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521)	0.671	11
Q12778	5	Ac-K245,K248,K265-FOXO1 [nucleoplasm] (R-HSA-9626942) FOXO1 [nucleoplasm] (R-HSA-199300) p-S218-FOXO1 [nucleoplasm] (R-HSA-5692651) p-T24,S256,S319-FOXO1 [cytosol] (R-HSA-211158) p-T24,S256,S319-FOXO1 [nucleoplasm] (R-HSA-199306)	0.671	5
P30307	8	CDC25C [cytosol] (R-HSA-157879) CDC25C [nucleoplasm] (R-HSA-69741) p-S191-CDC25C [nucleoplasm] (R-HSA-6802968) p-S198-CDC25C [cytosol] (R-HSA-8981697) p-S198-CDC25C [nucleoplasm] (R-HSA-156668) p-S216-CDC25C [cytosol] (R-HSA-75003) p-S216-CDC25C [nucleoplasm] (R-HSA-156496) p-T48,T67,S122,T130,S168,S214-CDC25C [cytosol] (R-HSA-8863654)	0.643	4
Q13627	1	DYRK1A [nucleoplasm] (R-HSA-1362267)	0.643	3
Q92574	1	TSC1 [plasma membrane] (R-HSA-165169)	0.643	3
P23945	1	FSHR [plasma membrane] (R-HSA-391380)	0.635	4
O43524	11	Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm] (R-HSA-9620514) Ac-K271,K290-FOXO3(?-673) [mitochondrial matrix] (R-HSA-9841849) FOXO3 [cytosol] (R-HSA-5687032) FOXO3 [nucleoplasm] (R-HSA-199305) FOXO3(?-673) [mitochondrial matrix] (R-HSA-9841824) p-S215 FOXO3 [cytosol] (R-HSA-5687014) p-S215 FOXO3 [nucleoplasm] (R-HSA-5687010) p-S43,S173,S294,S325-FOXO3 [cytosol] (R-HSA-8870560) p-S43,S173,S294,S325-FOXO3 [nucleoplasm] (R-HSA-8870627) p-T32,S253,S315-FOXO3 [cytosol] (R-HSA-9614413) p-T32,S253,S315-FOXO3 [nucleoplasm] (R-HSA-199289)	0.615	3
P13569	5	CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) CFTR G551D [plasma membrane] (R-HSA-5678977) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	15
Q08495	1	DMTN [cytosol] (R-HSA-5216222)	0.615	3
Q96ST8	1	CEP89 [cytosol] (R-HSA-5620930)	0.615	4
Q14678	1	KANK1 [nucleoplasm] (R-HSA-9018640)	0.589	2
P30304	7	CDC25A [nucleoplasm] (R-HSA-143487) p-S124,S178,S293-CDC25A [nucleoplasm] (R-HSA-9941808) p-S40,S116,S261-CDC25A [nucleoplasm] (R-HSA-8863634) p-S76,S124,S178,S279,S293-CDC25A [nucleoplasm] (R-HSA-143488) p-S76,S124-CDC25A [nucleoplasm] (R-HSA-9942581) p-S76,T80-CDC25A [nucleoplasm] (R-HSA-9943698) p-T80-CDC25A [nucleoplasm] (R-HSA-9943689)	0.569	3
Q96PU5	2	NEDD4L [cytosol] (R-HSA-976003) NEDD4L [nucleoplasm] (R-HSA-2176420)	0.569	3
P02671	1	FGA(20-35) [extracellular region] (R-HSA-140867)	0.564	2
Q9UDY2	3	TJP2 [cytosol] (R-HSA-2064412) TJP2 [plasma membrane] (R-HSA-351862) TJP2(?-?) [plasma membrane] (R-HSA-351897)	0.564	2
P10636	3	MAPT [cytosol] (R-HSA-201574) MAPT(2-421) [cytosol] (R-HSA-350628) MAPT(422-758) [cytosol] (R-HSA-350642)	0.547	2
O15530	3	p-S241-PDPK1 [cytosol] (R-HSA-9860799) PDPK1 [cytosol] (R-HSA-202210) PDPK1 [plasma membrane] (R-HSA-61459)	0.544	3
Q07955	1	SRSF1 [nucleoplasm] (R-HSA-72031)	0.536	2
O14757	2	CHEK1 [nucleoplasm] (R-HSA-113826) p-S317,S345-CHEK1 [nucleoplasm] (R-HSA-113838)	0.527	2
P00734	7	10xCbxE-F2(25-622) [endoplasmic reticulum lumen] (R-HSA-159800) 10xCbxE-F2(25-622) [Golgi lumen] (R-HSA-159841) 10xCbxE-F2(44-327) [extracellular region] (R-HSA-140786) 10xCbxE-F2(44-622) [extracellular region] (R-HSA-140674) 10xCbxE-F2(44-622) [Golgi lumen] (R-HSA-159845) F2(25-622) [endoplasmic reticulum lumen] (R-HSA-159739) prothrombin (factor II) propeptide [Golgi lumen] (R-HSA-159759)	0.527	2
P00747	1	PLG(20-810) [extracellular region] (R-HSA-158701)	0.527	2
P02675	1	FGB(31-44) [extracellular region] (R-HSA-140876)	0.527	2
P04004	1	VTN [extracellular region] (R-HSA-215971)	0.527	2
P29074	1	PTPN4 [cytosol] (R-HSA-8877173)	0.527	2
P31947	1	SFN [cytosol] (R-HSA-1445105)	0.527	2
P68871	1	HBB [cytosol] (R-HSA-1008196)	0.527	2
Q14966	1	ZNF638 [nucleoplasm] (R-HSA-8939429)	0.527	2
Q7Z3C6	1	ATG9A [phagophore assembly site membrane] (R-HSA-5671732)	0.527	2
Q8IX03	1	WWC1 [cytosol] (R-HSA-2038400)	0.527	2
Q96B36	2	AKT1S1 [cytosol] (R-HSA-200155) p-S183,T246-AKT1S1 [cytosol] (R-HSA-200163)	0.527	2
Q9BZF9	1	UACA [cytosol] (R-HSA-6804636)	0.527	2
Q9Y3M2	1	CBY1 [nucleoplasm] (R-HSA-3769210)	0.527	2
P32121	1	ARRB2 [cytosol] (R-HSA-416464)	0.499	3
P49407	1	ARRB1 [cytosol] (R-HSA-264470)	0.499	3
O00429	2	DNM1L [cytosol] (R-HSA-351943) DNM1L [mitochondrial outer membrane] (R-HSA-351942)	0.483	4
P00519	5	ABL1 [cytosol] (R-HSA-375987) ABL1 [nucleoplasm] (R-HSA-5686579) p-S456-ABL1 [nucleoplasm] (R-HSA-5686576) p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251) p-Y393-ABL1 [cytosol] (R-HSA-9865161)	0.483	2
P35568	1	IRS1 [cytosol] (R-HSA-74769)	0.483	2
P47974	1	ZFP36L2 [cytosol] (R-HSA-9819194)	0.483	3
Q07352	1	ZFP36L1 [cytosol] (R-HSA-450547)	0.483	3
Q6N021	1	TET2 [nucleoplasm] (R-HSA-5221011)	0.483	2
Q9H4G0	2	EPB41L1 [cytosol] (R-HSA-392241) EPB41L1 [plasma membrane] (R-HSA-416333)	0.483	2
Q9UQ84	1	EXO1 [nucleoplasm] (R-HSA-5357514)	0.483	2
Q6PJG9	1	SALM3 [plasma membrane] (R-HSA-197883)	0.462	3

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