Reactome | UniProt:P27986-2 PIK3R1

UniProt:P27986-2 PIK3R1

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

GRB1, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, AS53, ENSP00000338554.5

List of interactors in Reactome

Interactors (26)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P35568	1	IRS1 [cytosol] (R-HSA-74769)	0.57	3
Q9NP31	1	SH2D2A [cytosol] (R-HSA-4420125)	0.57	3
O76024	1	WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
P01100	2	FOS [nucleoplasm] (R-HSA-450216) p-T325,T331,S362,S374-FOS [nucleoplasm] (R-HSA-450283)	0.556	3
P05067	12	APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-713) [extracellular region] (R-HSA-879340) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325)	0.556	3
P05412	4	JUN [cytosol] (R-HSA-168194) JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [cytosol] (R-HSA-8868682) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237)	0.556	3
P05556	1	ITGB1 [plasma membrane] (R-HSA-57596)	0.556	3
P06493	6	CDK1 [cytosol] (R-HSA-170075) CDK1 [endoplasmic reticulum membrane] (R-HSA-264424) CDK1 [nucleoplasm] (R-HSA-68889) p-T161-CDK1 [cytosol] (R-HSA-157415) p-T161-CDK1 [nucleoplasm] (R-HSA-170066) p-Y4-CDK1 [cytosol] (R-HSA-9836187)	0.556	3
P07948	4	LYN [cytosol] (R-HSA-354251) LYN [plasma membrane] (R-HSA-197943) MyrG2-PalmC3-LYN [plasma membrane] (R-HSA-9606875) p-Y397-LYN [plasma membrane] (R-HSA-2454229)	0.556	3
P12931	5	MyrG-p-Y419-SRC [plasma membrane] (R-HSA-1810408) MyrG-SRC [plasma membrane] (R-HSA-8876922) p-Y419-SRC [cytosol] (R-HSA-8964276) p-Y419-SRC [nucleoplasm] (R-HSA-8937690) SRC [cytosol] (R-HSA-9628701)	0.556	3
P14136	3	GFAP [cytosol] (R-HSA-1253311) GFAP [lysosomal membrane] (R-HSA-9625195) p-GFAP [lysosomal membrane] (R-HSA-9626054)	0.556	3
P17612	2	PRKACA [cytosol] (R-HSA-57844) PRKACA [mitochondrial matrix] (R-HSA-9838291)	0.556	3
P34741	2	p-Y179,Y191-SDC2 [plasma membrane] (R-HSA-4093306) SDC2 [plasma membrane] (R-HSA-2090052)	0.556	3
P42336	1	PIK3CA [cytosol] (R-HSA-74787)	0.556	3
P42858	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	18
P51451	1	BLK [cytosol] (R-HSA-983580)	0.556	3
P62993	1	GRB2 [cytosol] (R-HSA-8983328)	0.556	3
P63000	1	RAC1 [cytosol] (R-HSA-442615)	0.556	3
P84022	2	p-S423,S425-SMAD3 [cytosol] (R-HSA-171184) SMAD3 [cytosol] (R-HSA-170855)	0.556	3
Q9NY61	1	AATF [cytosol] (R-HSA-205071)	0.556	3
Q9UNE7	1	STUB1 [cytosol] (R-HSA-975970)	0.556	3
O15524	1	SOCS1 [cytosol] (R-HSA-204910)	0.488	2
P22681	3	CBL [cytosol] (R-HSA-112199) p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-912656) PolyUb,p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-8848826)	0.488	2
P40763	6	p-S727-STAT3 [cytosol] (R-HSA-198705) p-STAT3 [cytosol] (R-HSA-8982823) p-Y705,S727-STAT3 [cytosol] (R-HSA-539048) p-Y705-STAT3 [cytosol] (R-HSA-914048) p-Y705-STAT3 [cytosol] (R-HSA-8983130) STAT3 [cytosol] (R-HSA-539044)	0.488	2
P46108	1	CRK [cytosol] (R-HSA-2980677)	0.488	2
Q9UKG1	1	APPL1 [endosome membrane] (R-HSA-373630)	0.488	2