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UniProt:P62258 YWHAE
Type
Interactor (Protein)
Species
Homo sapiens
Synonyms
1433E_HUMAN, B3KY71, D3DTH5, P29360, P42655, Q4VJB6, Q53XZ5, Q63631, Q7M4R4
List of interactors in Reactome
Interactors (79)
Accession
#Entities
Reactome Entity
Confidence Score
Evidence (IntAct)
P63104
2
YWHAZ [cytosol]
(R-HSA-206099)
YWHAZ [nucleoplasm]
(R-HSA-450469)
0.924
17
P31946
1
YWHAB [cytosol]
(R-HSA-48888)
0.919
15
P04049
3
hyperphosphorylated RAF1 [plasma membrane]
(R-HSA-5675193)
p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5672665)
RAF1 [cytosol]
(R-HSA-167205)
0.913
24
P56524
3
HDAC4 [nucleoplasm]
(R-HSA-351581)
monoSUMO1-K559-HDAC4 [nucleoplasm]
(R-HSA-4616016)
polySUMO2,3-K559-HDAC4 [nucleoplasm]
(R-HSA-4616029)
0.865
9
P15056
3
BRAF [cytosol]
(R-HSA-167224)
hyperphosphorylated BRAF [plasma membrane]
(R-HSA-5675199)
p-S446,T599,S602,S729 BRAF [plasma membrane]
(R-HSA-5672679)
0.859
10
P46937
8
p-5S-YAP1 [cytosol]
(R-HSA-2028554)
p-S127-YAP1 [cytosol]
(R-HSA-2028553)
p-Y-YAP1 [cytosol]
(R-HSA-8937843)
p-Y-YAP1 [nucleoplasm]
(R-HSA-8937857)
p-Y407-YAP1 [cytosol]
(R-HSA-9865208)
p-Y407-YAP1 [nucleoplasm]
(R-HSA-8956661)
YAP1 [cytosol]
(R-HSA-1253345)
YAP1 [nucleoplasm]
(R-HSA-1253322)
0.842
9
Q92934
4
BAD [cytosol]
(R-HSA-50662)
BAD [mitochondrial outer membrane]
(R-HSA-114242)
p-S91-BAD [cytosol]
(R-HSA-217297)
p-S99-BAD [cytosol]
(R-HSA-198335)
0.833
8
Q5S007
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.823
8
P22681
3
CBL [cytosol]
(R-HSA-112199)
p-Y700,Y731,Y774-CBL [cytosol]
(R-HSA-912656)
PolyUb,p-Y700,Y731,Y774-CBL [cytosol]
(R-HSA-8848826)
0.773
6
P30307
8
CDC25C [cytosol]
(R-HSA-157879)
CDC25C [nucleoplasm]
(R-HSA-69741)
p-S191-CDC25C [nucleoplasm]
(R-HSA-6802968)
p-S198-CDC25C [cytosol]
(R-HSA-8981697)
p-S198-CDC25C [nucleoplasm]
(R-HSA-156668)
p-S216-CDC25C [cytosol]
(R-HSA-75003)
p-S216-CDC25C [nucleoplasm]
(R-HSA-156496)
p-T48,T67,S122,T130,S168,S214-CDC25C [cytosol]
(R-HSA-8863654)
0.773
6
P00519
5
ABL1 [cytosol]
(R-HSA-375987)
ABL1 [nucleoplasm]
(R-HSA-5686579)
p-S456-ABL1 [nucleoplasm]
(R-HSA-5686576)
p-Y226,Y393-ABL1 [nucleoplasm]
(R-HSA-8985251)
p-Y393-ABL1 [cytosol]
(R-HSA-9865161)
0.763
6
P30305
3
CDC25B [cytosol]
(R-HSA-157412)
CDC25B [nucleoplasm]
(R-HSA-69734)
p-S50,T69,S160,S321,S470-CDC25B [cytosol]
(R-HSA-8863644)
0.763
6
P30304
4
CDC25A [nucleoplasm]
(R-HSA-143487)
p-S124-CDC25A [cytosol]
(R-HSA-69588)
p-S124-CDC25A [nucleoplasm]
(R-HSA-143488)
p-S40,S116,S261-CDC25A [nucleoplasm]
(R-HSA-8863634)
0.76
6
P35568
1
IRS1 [cytosol]
(R-HSA-74769)
0.76
8
Q9GZV5
3
p-S89-WWTR1 [cytosol]
(R-HSA-2028665)
WWTR1 [cytosol]
(R-HSA-1629773)
WWTR1 [nucleoplasm]
(R-HSA-1629775)
0.738
4
Q13627
1
DYRK1A [nucleoplasm]
(R-HSA-1362267)
0.734
5
Q96PU5
2
NEDD4L [cytosol]
(R-HSA-976003)
NEDD4L [nucleoplasm]
(R-HSA-2176420)
0.727
6
Q9NRR6
1
INPP5E [cytosol]
(R-HSA-1604585)
0.725
5
Q9Y3M2
1
CBY1 [nucleoplasm]
(R-HSA-3769210)
0.725
5
Q13233
2
MAP3K1 [cytosol]
(R-HSA-166866)
p-T1400,T1412-MAP3K1 [cytosol]
(R-HSA-2685607)
0.71
4
Q9UQC2
1
GAB2 [cytosol]
(R-HSA-508239)
0.706
5
O43524
11
Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm]
(R-HSA-9620514)
Ac-K271,K290-FOXO3(?-673) [mitochondrial matrix]
(R-HSA-9841849)
FOXO3 [cytosol]
(R-HSA-5687032)
FOXO3 [nucleoplasm]
(R-HSA-199305)
FOXO3(?-673) [mitochondrial matrix]
(R-HSA-9841824)
p-S215 FOXO3 [cytosol]
(R-HSA-5687014)
p-S215 FOXO3 [nucleoplasm]
(R-HSA-5687010)
p-S43,S173,S294,S325-FOXO3 [cytosol]
(R-HSA-8870560)
p-S43,S173,S294,S325-FOXO3 [nucleoplasm]
(R-HSA-8870627)
p-T32,S253,S315-FOXO3 [cytosol]
(R-HSA-9614413)
p-T32,S253,S315-FOXO3 [nucleoplasm]
(R-HSA-199289)
0.695
5
P49815
3
p-S939,S1130,T1462-TSC2 [cytosol]
(R-HSA-165164)
p-S939,T1462-TSC2 [cytosol]
(R-HSA-199484)
TSC2 [cytosol]
(R-HSA-2980548)
0.675
3
P26045
2
PTPN3 [cytosol]
(R-HSA-8867650)
PTPN3 [plasma membrane]
(R-HSA-5490317)
0.671
4
P57059
1
SIK1 [nucleoplasm]
(R-HSA-5656504)
0.669
4
P62258
1
YWHAE [cytosol]
(R-HSA-194368)
0.667
3
Q99683
1
MAP3K5 [cytosol]
(R-HSA-167709)
0.659
3
Q6PKG0
1
LARP1 [cytosol]
(R-HSA-9760421)
0.649
6
Q9UQB8
1
BAIAP2 [cytosol]
(R-HSA-442574)
0.649
7
Q02750
4
MAP2K1 [cytosol]
(R-HSA-59502)
MAP2K1(2-8) [cytosol]
(R-HSA-5211342)
MAP2K1(9-393) [cytosol]
(R-HSA-5211353)
p-S218,S222-MAP2K1 [cytosol]
(R-HSA-109837)
0.643
5
Q9BZ23
1
PANK2(111-570) [mitochondrial intermembrane space]
(R-HSA-196803)
0.643
3
Q9P0V3
1
SH3BP4 [cytosol]
(R-HSA-8866227)
0.64
4
Q12778
5
Ac-K245,K248,K265-FOXO1 [nucleoplasm]
(R-HSA-9626942)
FOXO1 [nucleoplasm]
(R-HSA-199300)
p-S218-FOXO1 [nucleoplasm]
(R-HSA-5692651)
p-T24,S256,S319-FOXO1 [cytosol]
(R-HSA-211158)
p-T24,S256,S319-FOXO1 [nucleoplasm]
(R-HSA-199306)
0.623
5
P13569
5
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.615
18
Q08495
1
DMTN [cytosol]
(R-HSA-5216222)
0.615
3
P31947
1
SFN [cytosol]
(R-HSA-1445105)
0.604
5
P40818
2
p-T945-USP8 [cytosol]
(R-HSA-1358714)
USP8 [cytosol]
(R-HSA-917720)
0.604
5
P47974
1
ZFP36L2 [cytosol]
(R-HSA-9819194)
0.604
5
P21580
1
TNFAIP3 [cytosol]
(R-HSA-688989)
0.573
3
O00443
1
PIK3C2A [cytosol]
(R-HSA-1604624)
0.569
4
P10636
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
0.569
11
P49757
1
NUMB [plasma membrane]
(R-HSA-443595)
0.569
4
Q02241
2
KIF23 [nucleoplasm]
(R-HSA-156709)
p-S911,S912-KIF23 [nucleoplasm]
(R-HSA-156695)
0.569
4
Q86TI0
2
p-S237-TBC1D1 [cytosol]
(R-HSA-1454673)
TBC1D1 [cytoplasmic vesicle membrane]
(R-HSA-1454718)
0.569
4
Q9Y4H2
1
IRS2 [cytosol]
(R-HSA-57528)
0.569
4
P46934
1
NEDD4 [cytosol]
(R-HSA-975992)
0.564
3
Q13322
1
GRB10 [cytosol]
(R-HSA-110009)
0.564
3
Q9H1K1
1
ISCU [cytosol]
(R-HSA-9771680)
0.564
3
Q14671
1
PUM1 [cytosol]
(R-HSA-434211)
0.539
5
A0MZ66
1
KIAA1598 [cytosol]
(R-HSA-443599)
0.527
2
P36507
4
MAP2K2 [cytosol]
(R-HSA-59504)
MAP2K2(1-10) [cytosol]
(R-HSA-5211334)
MAP2K2(11-400) [cytosol]
(R-HSA-5211337)
p-S,T-MAP2K2 [cytosol]
(R-HSA-109848)
0.527
3
P41743
2
PRKCI [cytosol]
(R-HSA-58206)
PRKCI [nucleoplasm]
(R-HSA-9021345)
0.527
2
P56945
2
BCAR1 [cytosol]
(R-HSA-201625)
p-Y165,Y664-BCAR1 [cytosol]
(R-HSA-8848723)
0.527
5
P62993
1
GRB2 [cytosol]
(R-HSA-8983328)
0.527
3
Q00613
6
HSF1 [cytosol]
(R-HSA-3371452)
HSF1 [nucleoplasm]
(R-HSA-5082385)
p-S121-HSF1 [cytosol]
(R-HSA-4793906)
p-S303,307-HSF1 [cytosol]
(R-HSA-4793922)
p-S303-HSF1 [cytosol]
(R-HSA-4793927)
p-S307-HSF1 [cytosol]
(R-HSA-4793929)
0.527
2
Q61337
6
Bad [cytosol]
(R-MMU-3139043)
Bad [cytosol]
(R-MMU-50662)
Bad [mitochondrial outer membrane]
(R-MMU-114242)
p-S136-Bad [cytosol]
(R-MMU-3139049)
phospho-Bad [cytosol]
(R-MMU-217297)
phospho-Bad [cytosol]
(R-MMU-198335)
0.527
2
Q70EL4
1
USP43 [nucleoplasm]
(R-HSA-5653784)
0.527
2
Q8IX03
1
WWC1 [cytosol]
(R-HSA-2038400)
0.527
2
Q8WX92
2
NELFB [cytosol]
(R-HSA-9603526)
NELFB [nucleoplasm]
(R-HSA-112427)
0.527
2
Q96L34
1
MARK4 [cytosol]
(R-HSA-5626653)
0.527
2
Q9NQC7
3
CYLD [cytosol]
(R-HSA-741420)
K48polyUb-K338, K530-CYLD [cytosol]
(R-HSA-9818664)
p-S418-CYLD [cytosol]
(R-HSA-5212667)
0.527
2
Q9P0N9
1
TBC1D7 [cytosol]
(R-HSA-8854154)
0.527
2
Q9P2Y5
1
UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-9730510)
0.527
2
Q96QF0
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.508
3
P21796
1
VDAC1 [mitochondrial outer membrane]
(R-HSA-1267988)
0.499
5
P36957
4
GlutaryllipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9858581)
Lipo-K110-DLST [mitochondrial matrix]
(R-HSA-69993)
LipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9853485)
SuccinyllipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9853502)
0.499
4
P49674
1
CSNK1E [cytosol]
(R-HSA-205877)
0.499
3
P49840
2
GSK3A [cytosol]
(R-HSA-198326)
p-Y279-GSK3A [cytosol]
(R-HSA-9635490)
0.499
3
O00429
2
DNM1L [cytosol]
(R-HSA-351943)
DNM1L [mitochondrial outer membrane]
(R-HSA-351942)
0.483
4
Q13009
1
TIAM1 [cytosol]
(R-HSA-195013)
0.483
2
Q6N021
1
TET2 [nucleoplasm]
(R-HSA-5221011)
0.483
2
Q92538
2
GBF1 [cytosol]
(R-HSA-6807751)
GBF1 [Golgi membrane]
(R-HSA-199994)
0.483
3
Q96RT1
1
ERBIN [plasma membrane]
(R-HSA-1358718)
0.483
3
Q96ST8
1
CEP89 [cytosol]
(R-HSA-5620930)
0.483
4
Q9HC77
2
CENPJ [cytosol]
(R-HSA-380291)
p-S589,S595-CENPJ [cytosol]
(R-HSA-6801670)
0.483
2
Q9NPI6
1
DCP1A [cytosol]
(R-HSA-430043)
0.483
2
Q9UQ84
1
EXO1 [nucleoplasm]
(R-HSA-5357514)
0.483
2
Q9Y580
1
RBM7 [nucleoplasm]
(R-HSA-8985564)
0.483
2
Q6PJG9
1
SALM3 [plasma membrane]
(R-HSA-197883)
0.462
3
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