Aziz Sancar

 ORCID
https://orcid.org/0000-0001-6469-4900
Reviewed Pathways (9/9)
Date Identifier Pathway Reference
2025-03-04 R-HSA-9931521 The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex BibTex
2025-02-14 R-HSA-9909396 Circadian clock BibTex
2025-02-14 R-HSA-9931512 Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters BibTex
2025-02-14 R-HSA-9931529 Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK BibTex
2025-02-14 R-HSA-9932298 Degradation of CRY and PER proteins BibTex
2025-02-14 R-HSA-9931530 Phosphorylation and nuclear translocation of the CRY:PER:kinase complex BibTex
2025-02-14 R-HSA-9933387 RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression BibTex
2025-02-14 R-HSA-9931509 Expression of BMAL (ARNTL), CLOCK, and NPAS2 BibTex
2025-02-14 R-HSA-9931510 Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes BibTex
Show all reviewed pathways...
Reviewed Reactions (15/111)
Date Identifier Reaction Reference
2025-02-14 R-HSA-9920716 CLOCK acetylates BMAL1 on lysine-538 BibTex
2025-02-14 R-MMU-9920709 Clock acetylates Bmal1 on lysine-544 (lysine-537 of isoform 2) BibTex
2025-02-14 R-HSA-9920724 p-T451,T461-CLOCK is phosphorylated on serines-440,441,446 BibTex
2025-02-14 R-MMU-9920703 p-T451,T461-Clock is phosphorylated on serines-440,441,446 BibTex
2025-02-14 R-HSA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 BibTex
2025-02-14 R-HSA-9932510 BTRC:CUL1:SKP1:RBX1 (SCF-beta-TrCP1) ubiquitinylates phosphorylated PER1,2,3 BibTex
2025-02-14 R-MMU-9932505 Btrc:Cul1:Skp1:Rbx1 ubiquitinylates phosphorylated Per1,2,3 BibTex
2025-02-14 R-HSA-9932506 BTRC:CUL1:SKP1:RBX1 binds phosphorylated PER protein BibTex
2025-02-14 R-MMU-9932534 Btrc:Cul1:Skp1:Rbx1 binds phosphorylated Per1,2,3 BibTex
2025-02-14 R-HSA-9934884 Proteolysis of K48polyUb,p-S-CRY1,2 BibTex
2025-02-14 R-MMU-9934892 Proteolysis of K48polyUb,p-S-Cry1,2 BibTex
2025-02-14 R-HSA-9932512 FBXL3:CUL1:SKP1:RBX1 ubiquitinylates phosphorylated CRY1,2 BibTex
2025-02-14 R-MMU-9932501 Fbxl3:Cul1:Skp1:Rbx1 ubiquitinylates phosphorylated Cry1,2 BibTex
2025-02-14 R-HSA-9934887 Proteolysis of K48polyUb-K107,p-S-CRY1,K48polyUb-K126,p-S-CRY2 BibTex
2025-02-14 R-MMU-9934888 Proteolysis of K48polyUb-K107,p-S-Cry1,K48polyUb-K125,p-S-Cry2 BibTex
Show all reviewed reactions...
Cite Us!