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About
What is Reactome ?
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Cytomics
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Go!
Karen Rothfels
ORCID
https://orcid.org/0000-0002-0705-7048
Are you Karen Rothfels ? Register or Connect your ORCID
Project
Reactome
Affiliation
Ontario Institute for Cancer Research
Expand All
Authored Pathways (15/229)
Date
Identifier
Pathway
Reference
2023-12-21
R-HSA-9856649
Transcriptional and post-translational regulation of MITF-M expression and activity
BibTex
2023-12-21
R-HSA-9856651
MITF-M-dependent gene expression
BibTex
2023-12-21
R-HSA-9854907
Regulation of MITF-M dependent genes involved in metabolism
BibTex
2023-12-21
R-HSA-9854909
Regulation of MITF-M dependent genes involved in invasion
BibTex
2023-12-21
R-HSA-9857377
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
BibTex
2023-10-14
R-HSA-9842663
Signaling by LTK
BibTex
2023-10-14
R-HSA-9842640
Signaling by LTK in cancer
BibTex
2023-10-14
R-HSA-9851151
MDK and PTN in ALK signaling
BibTex
2023-01-26
R-HSA-9730414
MITF-M-regulated melanocyte development
BibTex
2023-01-26
R-HSA-9824585
Regulation of MITF-M-dependent genes involved in pigmentation
BibTex
2023-01-26
R-HSA-9825892
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
BibTex
2023-01-26
R-HSA-9825895
Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence
BibTex
2023-01-26
R-HSA-9824594
Regulation of MITF-M-dependent genes involved in apoptosis
BibTex
2021-10-08
R-HSA-9755511
KEAP1-NFE2L2 pathway
BibTex
2021-10-08
R-HSA-9759194
Nuclear events mediated by NFE2L2
BibTex
Show all authored pathways...
Authored Reactions (15/1,498)
Date
Identifier
Reaction
Reference
2023-12-21
R-HSA-9858286
POU3F2 binds the MITF gene
BibTex
2023-12-21
R-HSA-9824995
GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405
BibTex
2023-12-21
R-NUL-9732096
FOXD3 binds PAX3
BibTex
2023-12-21
R-MMU-9858228
Alx3 binds the Mitf gene
BibTex
2023-12-21
R-HSA-9858238
AXL3 binds MITF promoter
BibTex
2023-12-21
R-HSA-9854920
MITF-M dimer binds SIRT1 promoter
BibTex
2023-12-21
R-HSA-9854916
MITF-M-dependent SIRT1 gene expression
BibTex
2023-12-21
R-HSA-9856460
MITF-M-dependent RAB27A expression
BibTex
2023-12-21
R-HSA-9856462
MITF-M-dependent MYO5A expression
BibTex
2023-12-21
R-HSA-9856464
MITF-M dimer binds MYO5A gene
BibTex
2023-12-21
R-HSA-9856466
MITF-M dimer binds RAB27A gene
BibTex
2023-12-21
R-HSA-9856056
MITF-M dimer binds GPR143 gene
BibTex
2023-12-21
R-HSA-9856053
MITF-M-dependent GPR143 expression
BibTex
2023-12-21
R-MMU-9855909
Mitf-m binds Smarca4, Smarcb1, Smarce1, Smarcd1
BibTex
2023-12-21
R-HSA-9856061
MITF-M-dependent CEACAM1 expression
BibTex
Show all authored reactions...
Reviewed Pathways (1/1)
Date
Identifier
Pathway
Reference
2016-09-17
R-HSA-3371497
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
BibTex
Show all reviewed pathways...
Reviewed Reactions (15/15)
Date
Identifier
Reaction
Reference
2016-09-17
R-HSA-5618093
ATP hydrolysis by HSP90
BibTex
2016-09-17
R-HSA-5618080
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus
BibTex
2016-09-17
R-HSA-9690534
NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex)
BibTex
2016-09-17
R-HSA-9705925
Androgens binds AR (in the HSP90 chaperone complex)
BibTex
2016-09-17
R-HSA-9725885
P4 bind PGR (in the HSP90 chaperone complex)
BibTex
2016-09-17
R-HSA-5618099
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex)
BibTex
2016-09-17
R-HSA-5618073
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein
BibTex
2016-09-17
R-HSA-5618098
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein
BibTex
2016-09-17
R-HSA-5618105
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein
BibTex
2016-09-17
R-HSA-5618110
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein
BibTex
2016-09-17
R-HSA-5618085
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein
BibTex
2016-09-17
R-HSA-5618107
ATP binding to HSP90 triggers conformation change
BibTex
2016-09-17
R-HSA-3371503
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein
BibTex
2016-09-17
R-HSA-3371422
ATP hydrolysis by HSP70
BibTex
2016-09-17
R-HSA-3371590
HSP70 binds to HSP40:nascent protein
BibTex
Show all reviewed reactions...
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