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Julhash U Kazi

 ORCID
https://orcid.org/0000-0002-0719-5336
Reviewed Reactions (79)
Date Identifier Reaction Reference
2020-11-06 R-HSA-9702570 KW2449-resistant FLT3 mutants don't bind KW2449 BibTex
2020-11-06 R-HSA-9702601 midostaurin-resistant FLT3 mutants don't bind midostaurin BibTex
2020-11-06 R-HSA-9702629 sunitinib-resistant FLT3 mutants don't bind sunitinib BibTex
2020-11-06 R-HSA-9702607 pexidartinib-resistant FLT3 mutants don't bind pexidartinib BibTex
2020-11-06 R-HSA-9702638 tandutinib-resistant FLT3 mutants don't bind tandutinib BibTex
2020-11-06 R-HSA-9703008 tamatinib-resistant FLT3 mutants don't bind tamatinib BibTex
2020-11-06 R-HSA-9702623 sorafenib-resistant FLT3 mutants don't bind sorafenib BibTex
2020-11-06 R-HSA-9702593 lestaurtinib-resistant FLT3 mutants don't bind lestaurtinib BibTex
2020-11-06 R-HSA-9702589 gilteritinib-resistant FLT3 mutants don't bind gilteritinib BibTex
2020-11-06 R-HSA-9702618 quizartinib-resistant FLT3 mutants don't bind quizartinib BibTex
2020-11-06 R-HSA-9702578 semaxanib-resistant FLT3 mutants don't bind semaxanib
 		BibTex
2020-11-06 R-HSA-9702997 linafinib-resistant FLT3 mutants don't bind linifanib BibTex
2020-11-06 R-HSA-9702613 ponatinib-resistant FLT3 mutants don't bind ponatinib BibTex
2020-11-06 R-HSA-9702583 crenolanib-resistant FLT3 mutants don't bind crenolanib BibTex
2020-11-06 R-HSA-9703434 FLT3 fusions recruit PIK3CA through PIK3R1 BibTex
2020-11-06 R-HSA-9703432 p-STAT5 dissociates from FLT3 fusion proteinsp- BibTex
2020-11-06 R-HSA-9703435 FLT3 fusions activate STAT5 BibTex
2020-11-06 R-HSA-9703439 FLT3 fusions recruit PIK3R1 through phosphorylated GAB2 BibTex
2020-11-06 R-HSA-9703438 FLT3 fusions phosphorylate GAB2 BibTex
2020-11-06 R-HSA-9703441 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 fusion mutants BibTex
2020-11-06 R-HSA-9703430 FLT3 fusions:GRB2 bind SOS1 BibTex
2020-11-06 R-HSA-9703440 FLT3 fusions:GRB2 bind GAB2 BibTex
2020-11-06 R-HSA-9703442 Phosphorylated FLT3 fusions bind GRB2 BibTex
2020-11-06 R-HSA-9703437 FLT3 fusion dimers autophosphorylate BibTex
2020-11-06 R-HSA-9703433 Ligand-independent dimerization of FLT3 fusion proteins BibTex
2020-11-06 R-HSA-9706356 CBL mutants don't ubiquitinate FLT3 BibTex
2020-11-06 R-HSA-9702510 FLT mutants bind type II TKIs BibTex
2020-11-06 R-HSA-9702508 FLT mutants bind type I TKIs BibTex
2020-11-06 R-HSA-9706345 Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA BibTex
2020-11-06 R-HSA-9706340 Active FLT3:p-Y-GRB10 binds PIK3R1 BibTex
2020-11-06 R-HSA-9706344 FLT3 phosphorylates GRB10 BibTex
2020-11-06 R-HSA-9699578 Active FLT3 phosphorylates CDKN1B BibTex
2020-11-06 R-HSA-9699581 AKT-phosphorylated FOXO3 translocates to cytosol BibTex
2020-11-06 R-HSA-9699579 AKT phosphorylates FOXO3 downstream of FLT3 BibTex
2020-11-06 R-HSA-9695838 Ligand-independent dimerization of FLT3 mutants BibTex
2020-11-06 R-HSA-9695834 Constitutive phosphorylation of FLT3 mutants BibTex
2020-11-06 R-HSA-9695841 FLT3 mutant dimers bind GRB2 BibTex
2020-11-06 R-HSA-9698000 FLT3 mutants:GRB2 bind GAB2 BibTex
2020-11-06 R-HSA-9698003 FLT3 mutants phosphorylate GAB2 BibTex
2020-11-06 R-HSA-9698179 FLT3 mutants recruit PIK3R1 through phosphorylated GAB2 BibTex
2020-11-06 R-HSA-9698008 FLT3 mutants:GRB2:p-Y-GAB2 binds PTPN11 BibTex
2020-11-06 R-HSA-9698007 FLT3 ITD mutants bind STAT5 through GAB2:PTPN11 BibTex
2020-11-06 R-HSA-9698005 FLT3 ITD mutants phosphorylate STAT5 BibTex
2020-11-06 R-HSA-9698029 p-STAT5 dissociates from mutant FLT3 BibTex
2020-11-06 R-HSA-9698033 p-STAT5 translocates to nucleus downstream of mutant FLT3 BibTex
2020-11-06 R-HSA-9698041 p-STAT5 binds the CDKN1A gene BibTex
2020-11-06 R-HSA-9698043 FLT3 ITD- and STAT5-dependent CDKN1A gene expression BibTex
2020-11-06 R-HSA-9698013 PTPN11:p-STAT5 dissociates from mutant FLT3 BibTex
2020-11-06 R-HSA-9698754 p-STAT5 binds the NOX4 promoter BibTex
2020-11-06 R-HSA-9698016 PTPN11:p-STAT5 translocates to nucleus downstream of mutant FLT3 BibTex
2020-11-06 R-HSA-9698762 FLT3 ITD- and STAT5-dependent NOX4 gene expression BibTex
2020-11-06 R-HSA-9698758 FLT3 ITD- and NOX4-dependent H2O2 production BibTex
2020-11-06 R-HSA-9698021 PTPN11:p-STAT5 binds BCL2L1 promoter BibTex
2020-11-06 R-HSA-9703436 STAT5-dependent PIM1 gene expression downstream of FLT3 ITD and fusion mutants BibTex
2020-11-06 R-HSA-9698026 FLT3 ITD- and STAT5-dependent BCL2L1 gene expression BibTex
2020-11-06 R-HSA-9695845 FLT3 mutant dimers:GRB2 bind SOS1 BibTex
2020-11-06 R-HSA-9698170 Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA BibTex
2020-11-06 R-HSA-9698174 FLT3 mutants recruit PIK3CA through PIK3R1 BibTex
2020-11-06 R-HSA-9695853 FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS BibTex
2020-11-06 R-HSA-9695831 FLT3 binds type II TKI BibTex
2020-11-06 R-HSA-9695828 FLT3 binds type I TKI BibTex
2020-11-06 R-HSA-9706308 Active FLT3 binds to GRB10 BibTex
2020-11-06 R-HSA-9706336 Active FLT3 binds to SYK BibTex
2020-11-06 R-HSA-9706312 Active FLT3 binds to LCK BibTex
2020-11-06 R-HSA-9706304 Active FLT3 binds to GRAP2 BibTex
2020-11-06 R-HSA-9706293 Active FLT3 binds to CBL BibTex
2020-11-06 R-HSA-9706350 FLT3 phosphorylates CBL BibTex
2020-11-06 R-HSA-9706354 Ubiquitination of FLT3 BibTex
2020-11-06 R-HSA-9706323 Active FLT3 binds to SLA2 BibTex
2020-11-06 R-HSA-9706364 Internalization of ubiquitinated FLT3 BibTex
2020-11-06 R-HSA-9698408 PTPRJ dephosphorylates active FLT3 BibTex
2020-11-06 R-HSA-9706319 Active FLT3 binds to SLA BibTex
2020-11-06 R-HSA-9706287 Active FLT3 binds to ABL2 BibTex
2020-11-06 R-HSA-9706328 Active FLT3 binds to SOCS2 BibTex
2020-11-06 R-HSA-9706330 Active FLT3 binds to SOCS6 BibTex
2020-11-06 R-HSA-9706298 Active FLT3 binds to CSK BibTex
2020-11-06 R-HSA-9706315 Active FLT3 binds to SH2B3 BibTex
2020-11-06 R-HSA-9699574 FOXO3-dependent BCL2L11 gene expression BibTex
2020-11-06 R-HSA-9699575 FOXO3-dependent CDKN1B gene expression BibTex
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