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Lauren Thorpe
ORCID
https://orcid.org/0000-0002-5302-9136
Are you Lauren Thorpe ? Register or Connect your ORCID
Affiliation
Dana-Farber Cancer Institute, Harvard Medical School
Reviewed Reactions (34)
Date
Identifier
Reaction
Reference
2012-08-13
R-HSA-2400009
PI3K inhibitors block PI3K catalytic activity
BibTex
2012-08-13
R-HSA-2394007
PI3K gain of function mutants phosphorylate PIP2 to PIP3
BibTex
2012-08-13
R-HSA-2399992
AKT1 E17K mutant phosphorylates forkhead box transcription factors
BibTex
2012-08-13
R-HSA-2399999
AKT1 E17K mutant phosphorylates RSK
BibTex
2012-08-13
R-HSA-2399966
AKT1 E17K mutant phosphorylates GSK3
BibTex
2012-08-13
R-HSA-2399996
AKT1 E17K mutant phosphorylates CREB1
BibTex
2012-08-13
R-HSA-2399985
AKT1 E17K mutant phosphorylates caspase-9
BibTex
2012-08-13
R-HSA-2399988
AKT1 E17K mutant phosphorylates NR4A1 (NUR77)
BibTex
2012-08-13
R-HSA-2399997
AKT1 E17K mutant translocates to the nucleus
BibTex
2012-08-13
R-HSA-2400010
AKT inhibitors block AKT membrane recruitment
BibTex
2012-08-13
R-HSA-2399977
AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40)
BibTex
2012-08-13
R-HSA-2399982
AKT1 E17K mutant phosphorylates TSC2, inhibiting it
BibTex
2012-08-13
R-HSA-2399981
AKT1 E17K mutant phosphorylates MDM2
BibTex
2012-08-13
R-HSA-2400001
AKT1 E17K mutant phosphorylates CHUK (IKKalpha)
BibTex
2012-08-13
R-HSA-2399969
AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1
BibTex
2012-08-13
R-HSA-2399941
AKT1 E17K mutant phosphorylates BAD
BibTex
2012-08-13
R-HSA-2243942
PDPK1 phosphorylates AKT1 E17K mutant
BibTex
2012-08-13
R-HSA-2243937
PIP2-bound p-S473-AKT1 mutant binds PIP2-bound PDPK1
BibTex
2012-08-13
R-HSA-2243938
AKT1 E17K mutant is phosphorylated by TORC2 complex
BibTex
2012-08-13
R-HSA-2219536
AKT1 E17K mutant binds PIP2
BibTex
2012-08-13
R-HSA-2317387
PTEN cancer mutants do not dephosphorylate PIP3
BibTex
2012-08-13
R-HSA-199425
PHLPP dephosphorylates S473 in AKT
BibTex
2012-08-13
R-HSA-199443
THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation
BibTex
2012-08-13
R-HSA-2219524
PDPK1 binds PIP2
BibTex
2012-08-13
R-HSA-198270
PDPK1 phosphorylates AKT at T308
BibTex
2012-08-13
R-HSA-2317314
AKT binds PDPK1
BibTex
2012-08-13
R-HSA-2316429
PIP3 recruits PDPK1 to the membrane
BibTex
2012-08-13
R-HSA-198640
TORC2 (mTOR) phosphorylates AKT at S473
BibTex
2012-08-13
R-HSA-2317332
PIP3 recruits AKT to the membrane
BibTex
2012-08-13
R-HSA-2316434
PI3K phosphorylates PIP2 to PIP3
BibTex
2012-08-13
R-HSA-199456
PTEN dephosphorylates PIP3
BibTex
2012-08-13
R-HSA-8944497
PTEN mRNA translation is negatively regulated by microRNAs
BibTex
2012-08-13
R-HSA-2321904
PTEN mRNA translation negatively regulated by microRNAs
BibTex
2012-08-13
R-HSA-2318752
miR-26A microRNAs bind PTEN mRNA
BibTex
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