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Rachel Huddart

 ORCID
https://orcid.org/0000-0002-5332-8312
Reviewed Reactions (168)
Date Identifier Reaction Reference
2022-03-01 R-HSA-9009817 Acitretin binds to RAR:RXR BibTex
2022-03-01 R-HSA-9716947 ESR1 binds ESR1 agonists BibTex
2022-03-01 R-HSA-9716913 ESR1 binds ESR1 antagonists BibTex
2022-03-01 R-HSA-9709454 EPOR binds EPOR agonists BibTex
2022-03-01 R-HSA-9733292 AMY1-3 bind pramlintide BibTex
2022-03-01 R-HSA-9702818 CALCR binds erenumab BibTex
2022-03-01 R-HSA-9702354 CALCA(83-119) binds CALCA antibodies BibTex
2022-03-01 R-HSA-9702849 CALCR binds gepants BibTex
2022-03-01 R-HSA-9703895 CASR binds CASR agonists BibTex
2022-03-01 R-HSA-9726875 HCNs:cAMP bind SNIs BibTex
2022-03-01 R-HSA-9727607 MME:Zn2+ binds sacubitrilat BibTex
2022-03-01 R-HSA-9727567 CES1 hydrolyses sacubitril to sacubitrilat BibTex
2022-03-01 R-HSA-9614031 Class IV antihypertensives bind LTCC multimer BibTex
2022-03-01 R-HSA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE BibTex
2022-03-01 R-HSA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers BibTex
2022-03-01 R-HSA-9691566 KCNJ11:ABCC9 binds nicorandil BibTex
2022-03-01 R-HSA-9708104 PDE5A dimer binds PDE5A inhibitors BibTex
2022-03-01 R-HSA-9620456 sGC stimulators bind sGC:NO BibTex
2022-03-01 R-HSA-9620103 ALDH2 transforms GTN to NO BibTex
2022-03-01 R-HSA-9700701 T-type VDCC bind T-type VDCC blockers BibTex
2022-03-01 R-HSA-9621179 Cinaciguat binds sGC:NO BibTex
2022-03-01 R-HSA-9709179 DPP4 binds DPP4 inhibitors BibTex
2022-03-01 R-HSA-9707186 ALOX5 binds ALOX5 inhibitors BibTex
2022-03-01 R-HSA-9734475 PPARA binds fibrates BibTex
2022-03-01 R-HSA-9726949 PTGIR binds PTGIR agonists BibTex
2022-03-01 R-HSA-9724745 PLG(20-810) binds aprotinin BibTex
2022-03-01 R-HSA-9724753 PLG(20-810) binds anti-fibrinolytics BibTex
2022-03-01 R-HSA-9708866 pro-F2R binds vorapaxar BibTex
2022-03-01 R-HSA-9756136 PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV BibTex
2022-03-01 R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL BibTex
2022-03-01 R-HSA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region BibTex
2022-03-01 R-HSA-9756150 PON1,3 hydrolyse 4-OH-ATVL to 4-OH-ATV BibTex
2022-03-01 R-HSA-9756177 PON1,3 hydrolyse ATVL to ATV BibTex
2022-03-01 R-HSA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL BibTex
2022-03-01 R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV BibTex
2022-03-01 R-HSA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL BibTex
2022-03-01 R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV BibTex
2022-03-01 R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL BibTex
2022-03-01 R-HSA-9756156 UGT1A3 lactonizes ATV to ATVL BibTex
2022-03-01 R-HSA-9677320 PTGS1 dimer binds PTGS1 Inhibitors BibTex
2022-03-01 R-HSA-9714580 SLC6A3 binds DRIs BibTex
2022-03-01 R-HSA-9714415 SLC6A4 binds TCAs and SSRIs BibTex
2022-03-01 R-HSA-9650858 Meglitinides bind ABCC8 BibTex
2022-03-01 R-HSA-9728664 GLP1R binds GLP1R agonists BibTex
2022-03-01 R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) BibTex
2022-03-01 R-HSA-9732527 FFAR1 binds rosiglitazone BibTex
2022-03-01 R-HSA-9700266 CFTR F508del binds CFTR correctors BibTex
2022-03-01 R-HSA-9678766 CYP3A4 binds CYP3A4 inhibitors BibTex
2022-03-01 R-HSA-9680865 CYP3A4, CYP2B6 bind ritonavir BibTex
2022-03-01 R-HSA-9677917 MAOA inhibitors bind MAOA:FAD BibTex
2022-03-01 R-HSA-9677929 MAOB inhibitors bind MAOB:FAD BibTex
2022-03-01 R-HSA-9707353 CYP19A1 binds Aromatase inhibitors BibTex
2022-03-01 R-HSA-9705794 SRD5A2 binds SRD5A2 inhibitors BibTex
2022-03-01 R-HSA-9709109 DHFR dimer binds DHFR inhibitors BibTex
2022-03-01 R-HSA-9732629 PPARG binds PPARG agonists BibTex
2022-03-01 R-HSA-9726509 NR3C2 binds fludrocortisone BibTex
2022-03-01 R-HSA-9705926 AR binds AR agonists BibTex
2022-03-01 R-HSA-9725855 NR3C2 binds NR3C2 antagonists BibTex
2022-03-01 R-HSA-9726621 PGR binds PGR antagonists BibTex
2022-03-01 R-HSA-9706837 AR binds AR antagonists BibTex
2022-03-01 R-HSA-9726580 PGR binds PGR agonists BibTex
2022-03-01 R-HSA-9727188 ATP4A:ATP4B binds PPIs BibTex
2022-03-01 R-HSA-9649963 ASIC3 channel blockers bind ASIC3 trimer BibTex
2022-03-01 R-HSA-9701147 TRPV1 binds TRPV1 blockers BibTex
2022-03-01 R-HSA-9701211 TRPA1 tetramer binds TRPA1 antagonists BibTex
2022-03-01 R-HSA-9701064 TRPV1 binds TRPV1 agonists BibTex
2022-03-01 R-HSA-9623384 ?1-agonists bind ADRA1A,B,D BibTex
2022-03-01 R-HSA-9611751 ?1,2-agonists bind ADRB1,2 BibTex
2022-03-01 R-HSA-9611721 ?1-agonists bind ADRB1 BibTex
2022-03-01 R-HSA-9689680 IFNG dimer binds IFNG inhibitors BibTex
2022-03-01 R-HSA-9691621 C5 binds C5 inhibitors BibTex
2022-03-01 R-HSA-9724670 C-ter TLR7 dimer binds imiquimod BibTex
2022-03-01 R-HSA-9692376 BCL2 binds BCL2 antagonists BibTex
2022-03-01 R-HSA-9691421 BTK binds BTK inhibitors BibTex
2022-03-01 R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer BibTex
2022-03-01 R-HSA-9708759 DHODH:FMN binds DHODH inhibitors BibTex
2022-03-01 R-HSA-9660192 VDR agonists bind VDR BibTex
2022-03-01 R-HSA-9717841 holo-FDPS dimer binds NBPs BibTex
2022-03-01 R-HSA-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol BibTex
2022-03-01 R-HSA-9705584 HMGCR dimer binds statins BibTex
2022-03-01 R-HSA-9695917 SPHK2 binds SPHK2 inhibitors BibTex
2022-03-01 R-HSA-9731931 EDNRA binds selective ERAs BibTex
2022-03-01 R-HSA-9731393 EDNRA, EDNRB bind non-selective ERAs BibTex
2022-03-01 R-HSA-9667619 AVPR1A,B,2 bind atosiban BibTex
2022-03-01 R-HSA-9667569 AVPR1A,2 bind AVPR antagonists BibTex
2022-03-01 R-HSA-9667456 AVPR1A,B bind desmopressin BibTex
2022-03-01 R-HSA-9667563 AVPR2 bind desmopressin BibTex
2022-03-01 R-HSA-9696323 CNRs bind CNR agonists BibTex
2022-03-01 R-HSA-9718360 GNRHR binds GNRHR peptide agonists BibTex
2022-03-01 R-HSA-9718394 GNRHR binds GNRHR peptide antagonists BibTex
2022-03-01 R-HSA-9718379 GNRHR binds chemical antagonists BibTex
2022-03-01 R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists BibTex
2022-03-01 R-HSA-9704248 CHRM4 binds CHRM4 antagonists BibTex
2022-03-01 R-HSA-9704297 CHRM2 binds CHRM2 antagonists BibTex
2022-03-01 R-HSA-9626914 ?2-agonists bind ADRA2A,B,C BibTex
2022-03-01 R-HSA-9617370 ?1-antagonists bind ADRA1A,B,D BibTex
2022-03-01 R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 BibTex
2022-03-01 R-HSA-9692867 HRH3 binds pitosilant BibTex
2022-03-01 R-HSA-9692738 HRH2 binds HRH2 antagonists BibTex
2022-03-01 R-HSA-9692539 HRH1 binds HRH1 inverse agonists BibTex
2022-03-01 R-HSA-9693478 HTR1A binds HTR1A agonists BibTex
2022-03-01 R-HSA-9648268 HTR1A binds HTR1A antagonists BibTex
2022-03-01 R-HSA-9718020 PTGFR binds PTGFR agonists BibTex
2022-03-01 R-HSA-9708275 PDE4A binds PDE4A inhibitors BibTex
2022-03-01 R-HSA-9629679 PDE3A inhibitors bind PDE3A BibTex
2022-03-01 R-HSA-9725706 SLC12A3 binds SLC12A3 inhibitors BibTex
2022-03-01 R-HSA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA BibTex
2022-03-01 R-HSA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs BibTex
2022-03-01 R-HSA-9707827 Spike binds Spike inhibitors BibTex
2022-03-01 R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors BibTex
2022-03-01 R-HSA-9728150 SLC5A2 binds gliflozins BibTex
2022-03-01 R-HSA-9733403 PCSK9 binds PCSK9 inhibitors BibTex
2022-03-01 R-HSA-9659611 ANO1 inhibitors bind ANO1 BibTex
2021-10-19 R-HSA-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 BibTex
2021-10-19 R-HSA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP BibTex
2021-10-19 R-HSA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP BibTex
2021-10-19 R-HSA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP BibTex
2021-10-19 R-HSA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP BibTex
2021-10-19 R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region BibTex
2021-10-19 R-HSA-9748991 XDH oxidises 6MP to 6TU BibTex
2021-10-19 R-HSA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region BibTex
2021-10-19 R-HSA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP BibTex
2021-10-19 R-HSA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP BibTex
2021-10-19 R-HSA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol BibTex
2021-10-19 R-HSA-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol BibTex
2021-10-19 R-HSA-9751051 GSH cleaves AZA to 6MP BibTex
2021-10-19 R-HSA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP BibTex
2021-10-19 R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP BibTex
2021-10-19 R-HSA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP BibTex
2021-10-19 R-HSA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP BibTex
2021-10-19 R-HSA-9748996 GST dimers cleave AZA to 6MP BibTex
2021-10-13 R-HSA-9750666 ALB binds ST BibTex
2021-10-13 R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells BibTex
2021-10-13 R-HSA-9750660 Glycine conjugates translocates from mitochondrial matrix to cytosol BibTex
2021-10-13 R-HSA-9757459 ST metabolites diffuse out of ER lumen BibTex
2021-10-13 R-HSA-9749977 UGT1A6 glucuronates ST BibTex
2021-10-13 R-HSA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA BibTex
2021-10-13 R-HSA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid BibTex
2021-10-13 R-HSA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA BibTex
2021-10-13 R-HSA-9757456 2,5-DHBA translocates from ER lumen to mitochondrial matrix BibTex
2021-10-13 R-HSA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA BibTex
2021-10-13 R-HSA-9757462 Hydroxyl radicals oxidize ST to 2,3-DHBA BibTex
2021-10-13 R-HSA-9749590 ASA- acetylates ALB BibTex
2021-10-13 R-HSA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 BibTex
2021-10-13 R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region BibTex
2021-10-13 R-HSA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer BibTex
2021-10-13 R-HSA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly BibTex
2021-10-13 R-HSA-9753634 GGT dimers hydrolyse APAP-SG BibTex
2021-10-13 R-HSA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG BibTex
2021-10-13 R-HSA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 BibTex
2021-10-13 R-HSA-158546 UGTs glucuronate APAP to APAP-GlcA BibTex
2021-10-13 R-HSA-9753277 SULT dimers sulfate APAP to APAP-SO3 BibTex
2021-10-13 R-HSA-9753916 NAPQI binds proteins in hepatocytes BibTex
2021-10-13 R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI BibTex
2021-10-13 R-HSA-9754180 APAP translocates from extracellular region to cytosol BibTex
2021-10-13 R-HSA-9749792 CES1,CES2 hydrolyze ASA- to ST BibTex
2021-10-13 R-HSA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys BibTex
2021-10-13 R-HSA-9757454 ST translocates from cytosol to mitochondrial matrix of hepatocytes BibTex
2021-10-13 R-HSA-9757451 ASA-,ST translocate from cytosol to ER lumen of hepatocytes BibTex
2021-10-13 R-HSA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes BibTex
2021-10-13 R-HSA-9749609 BCHE hydrolyzes ASA- BibTex
2021-10-13 R-HSA-9757448 ST translocates from cytosol to extracellular region BibTex
2021-10-13 R-HSA-9757441 ASA- (GI) translocates from cytosol to extracellular region BibTex
2021-10-13 R-HSA-9757445 ST translocates from ER lumen to cytosol of GI cells BibTex
2021-10-13 R-HSA-9749647 CES2 hydrolyzes ASA- BibTex
2021-10-13 R-HSA-9757438 ASA- translocates from cytosol to ER lumen of GI cells BibTex
2021-10-13 R-HSA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells BibTex
2021-10-13 R-HSA-9757434 Acetylsalicylic acid dissolves BibTex
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