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Marc E Gillespie

 ORCID
https://orcid.org/0000-0002-5766-1702
Project
Reactome
Affiliation
St. John's University, Cold Spring Harbor Laboratory, NYU School of Medicine, Department of Biochemistry
Authored Reactions (180)
Date Identifier Reaction Reference
2020-09-09 R-HSA-9681514 TMPRSS2 binds TMPRSS2 inhibitors BibTex
2020-09-09 R-HSA-9683467 CQ, HCQ are protonated to CQ2+, HCQ2+ BibTex
2020-09-09 R-HSA-9683478 CQ, HCQ diffuses from cytosol to endocytic vesicle lumen BibTex
2020-09-09 R-HSA-9685655 CTSL bind CTSL inhibitors BibTex
2020-09-09 R-HSA-9699007 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis BibTex
2020-09-09 R-HSA-9697423 Endocytosis of SARS-CoV-2 Virion BibTex
2020-09-09 R-HSA-9694287 Cleavage of S protein into S1:S2 BibTex
2020-09-09 R-HSA-9698988 Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid BibTex
2020-09-09 R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell BibTex
2020-09-09 R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis BibTex
2020-09-09 R-HSA-9694689 Fusion and Release of SARS-CoV-2 Nucleocapsid BibTex
2020-09-09 R-HSA-9694723 Uncoating of SARS-CoV-2 Genome BibTex
2020-05-26 R-HSA-9686711 Endocytois of SARS-CoV-1 Virion BibTex
2020-05-05 R-HSA-9686731 TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis BibTex
2020-05-05 R-HSA-9686710 Cleavage of S protein into S1:S2 BibTex
2020-05-05 R-HSA-9686699 Fusion and Release of SARS-CoV-1 Nucleocapsid BibTex
2020-05-05 R-HSA-9686709 Uncoating of SARS-CoV-1 Genome BibTex
2020-04-22 R-HSA-9678128 Spike glycoprotein of SARS coronavirus binds ACE2 on host cell BibTex
2019-11-12 R-HSA-9698931 C Nucleocapsid Assembly BibTex
2019-03-09 R-HSA-9640368 Addition of Tegument to HCMV Nucleocapsid C BibTex
2019-02-12 R-HSA-9698924 B Nucleocapsid Assembly BibTex
2019-02-12 R-HSA-9698933 HCMV B Nucleocapsid Translocation BibTex
2019-02-12 R-HSA-9698930 HCMV C Nucleocapsid Translocation BibTex
2018-11-28 R-HSA-9698926 HCMV Genome Replication Completion BibTex
2018-11-28 R-HSA-9698929 pPR-AP:pAP cleaves the MCP:pPR-AP:pAP Complex BibTex
2018-11-28 R-HSA-9636128 Translocation of SCP, Triplex (TRI) complex, CVC complex, and Accessory Proteins from the cytoplasm into the nucleous BibTex
2018-11-28 R-HSA-9698932 Assembly of HCMV Procapsid BibTex
2018-11-28 R-HSA-9698925 Packaging of Viral Genome Into C Capsids BibTex
2018-10-03 R-HSA-9624033 Initiation of HCMV DNA Replication BibTex
2018-10-03 R-HSA-9698927 Assembly of the HCMV Genome DNA Replication Complex BibTex
2018-07-25 R-HSA-9614810 Activation of Latent HCMV Genome BibTex
2018-06-20 R-HSA-9614343 Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs BibTex
2018-06-14 R-HSA-9611147 Endocytic Uptake of HCMV Virion BibTex
2018-06-14 R-HSA-9611158 Fusion of HCMV Envelope with Plasma Membrane BibTex
2018-05-30 R-HSA-9610867 HCMV Binds Host Cell Receptor - Endocytic Pathway BibTex
2018-05-30 R-HSA-9609689 HCMV Binds to the Host Cell via heparan sulfate proteoglycans (HSPG) BibTex
2017-01-27 R-HSA-8959573 Phosphorylated FUNDC1 links damaged mitochondria to LC3 BibTex
2016-11-11 R-HSA-8948039 FUNDC1 is phosphorylated by CK2 BibTex
2016-11-02 R-HSA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 BibTex
2016-11-02 R-HSA-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 BibTex
2016-11-02 R-HSA-8948139 p-S13-FUNDC1 is dephosphorylated by PGAM5 BibTex
2016-11-02 R-HSA-8948136 ULK1 Translocates to the mitochondria BibTex
2014-05-30 R-HSA-5632970 MSH6 variant:MSH2-defective DNA mismatch repair BibTex
2014-05-30 R-HSA-5578663 MSH3 variant:MSH2-defective DNA mismatch repair BibTex
2014-05-24 R-HSA-5577259 MSH2 variant:MSH3-defective DNA mismatch repair BibTex
2014-05-24 R-HSA-5577244 MSH2 variant:MSH6-defective DNA mismatch repair BibTex
2014-05-21 R-HSA-5545484 MLH1 variants-defective DNA mismatch repair BibTex
2014-05-21 R-HSA-5632958 PMS2 variants-defective DNA mismatch repair BibTex
2014-05-09 R-HSA-5444511 Formation of MSH2:MSH3 Complex BibTex
2014-05-09 R-HSA-5444523 Formation of MSH1:PMS2 Complex BibTex
2014-05-09 R-HSA-5444516 Formation of MSH2:MSH6 Complex BibTex
2013-11-21 R-HSA-8959571 LC3 binds the autophagosome membrane Atg5-Atg12 complex BibTex
2013-11-21 R-HSA-5205681 Pink1 is cleaved on healthy mitochondria BibTex
2013-11-21 R-HSA-5205661 Pink1 is recruited from the cytoplasm to the mitochondria BibTex
2013-11-21 R-HSA-5205672 Uncleaved Pink1 accumulates in damaged mitochondria BibTex
2013-11-21 R-HSA-5205652 Pink1 recruits Parkin to the outer mitochondrial membrane. BibTex
2013-11-21 R-HSA-5205682 Parkin promotes the ubiquitination of mitochondrial substrates BibTex
2013-11-21 R-HSA-5205673 p62 binds ubiquitinated mitochondrial substrates BibTex
2013-11-21 R-HSA-5205649 p62 links damaged mitochondria to LC3 BibTex
2013-11-21 R-HSA-5205663 LC3 binds the autophagosome membrane Atg5-Atg12 complex BibTex
2013-11-18 R-HSA-168878 PB1-F2 binds to the mitochondrial adenine nucleotide translocator 3 ANT3, inducing apoptosis BibTex
2013-11-18 R-HSA-168865 NA activation of TGF-beta BibTex
2013-11-18 R-HSA-6791035 Release of NS1 homodimer BibTex
2013-11-18 R-HSA-168859 Binding of NS1 to cleavage and host polyadenylation specificity factor (CPSF) BibTex
2013-11-18 R-HSA-168883 Binding of NS1 to poly(A)-binding protein II (PABII) BibTex
2013-11-18 R-HSA-168891 Binding of NS1 to dsRNA BibTex
2013-11-18 R-HSA-1176059 Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus BibTex
2013-11-18 R-HSA-168896 NS1 binds PKR BibTex
2013-03-07 R-HSA-3139027 Maturation of HIV Virion BibTex
2013-03-07 R-HSA-3159227 HIV Virion Budding BibTex
2013-03-07 R-HSA-3159232 Recruitment Of HIV Virion Budding Machinery BibTex
2013-03-07 R-HSA-3149454 Packaging of HIV virion on the host cell plasma membrane BibTex
2013-03-07 R-HSA-187213 Synthesis of GAG polyprotein BibTex
2013-03-07 R-HSA-184269 Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex BibTex
2013-03-07 R-HSA-3149434 Transport of GAG to the Plasma Membrane BibTex
2013-03-07 R-HSA-184392 N-myristoylation of GAG polyprotein by NMT2 BibTex
2013-03-07 R-HSA-184323 Monoubiquitination of N-myristoyl GAG polyprotein BibTex
2013-03-07 R-HSA-173647 Transport of trimeric gp41:gp120 to plasma membrane BibTex
2013-03-07 R-HSA-174491 Transport of trimeric ENV precursor to Golgi apparatus BibTex
2013-03-07 R-HSA-174494 Synthesis of ENV polyprotein BibTex
2013-03-07 R-HSA-174493 Glycosylation of ENV polyprotein BibTex
2013-03-07 R-HSA-3149432 Transport of VPU to Plasma Membrane BibTex
2013-03-07 R-HSA-187211 Splicing of HIV RNA transcript BibTex
2013-03-07 R-HSA-3149433 Synthesis of VPU protein BibTex
2013-03-07 R-HSA-3149440 Transport of VPU to Golgi apparatus BibTex
2013-02-13 R-HSA-1297275 CD9:Izumo Binding BibTex
2013-02-13 R-HSA-1297354 Acrosin Cleavage BibTex
2013-02-13 R-HSA-1297333 Association of Acrosin Heavy and Light Chain BibTex
2013-02-13 R-HSA-2534346 SPAM1 Binds Hyaluronic Acid BibTex
2013-02-13 R-HSA-1297338 Association of ADAM and B4GALT1 With ZP3 BibTex
2013-02-13 R-HSA-2534378 Hv1 Mediated H+ Permeability BibTex
2013-02-13 R-HSA-2534365 Slo3 Potassium Transport BibTex
2013-02-13 R-HSA-2534388 Progesterone Activation Of CatSper BibTex
2013-02-13 R-HSA-2534359 CatSper Channel Mediated Calcium Transport BibTex
2010-08-10 R-HSA-917730 Cargo Recognition And Sorting BibTex
2010-08-10 R-HSA-917696 Cargo Sequestration BibTex
2010-08-10 R-HSA-917700 MVB Vesicle Formation BibTex
2010-08-10 R-HSA-917693 ESCRT Disassembly BibTex
2009-11-18 R-HSA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains BibTex
2009-08-27 R-HSA-376364 Vamp8 associated secretory vesicle to plasma membrane transport BibTex
2009-08-27 R-HSA-376369 Vamp2 associated secretory vesicle to plasma membrane transport BibTex
2009-08-27 R-HSA-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture BibTex
2009-08-27 R-HSA-421831 trans-Golgi Network Coat Assembly BibTex
2009-08-27 R-HSA-421835 trans-Golgi Network Vesicle Scission BibTex
2009-08-27 R-HSA-421836 trans-Golgi Network Derived Vesicle Uncoating BibTex
2009-08-27 R-HSA-429815 Formation Of Bloc-1 Complex BibTex
2009-08-27 R-HSA-350769 trans-Golgi Network Coat Activation BibTex
2009-08-27 R-HSA-432712 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane BibTex
2009-08-27 R-HSA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly BibTex
2009-08-27 R-HSA-432707 trans-Golgi Network Lysosomal Vesicle Scission BibTex
2009-08-27 R-HSA-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating BibTex
2009-08-27 R-HSA-376357 Vamp7 associated Lysosome to Plasma membrane transport BibTex
2009-08-13 R-HSA-434362 Recruitment Of Cytoplasmic Proteins To Vesicles BibTex
2009-02-23 R-HSA-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication BibTex
2009-02-23 R-HSA-375342 Connexin 36 mediated neuronal gap junction communication BibTex
2009-02-23 R-HSA-375340 Connexin 62 mediated neuronal gap junction communication BibTex
2009-02-23 R-HSA-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication BibTex
2009-02-10 R-HSA-445797 MYLK (MLCK) Active Calmodulin Binding BibTex
2007-07-25 R-HSA-182286 Transport of MHC I:Nef:AP-1:PACS-1 Complex BibTex
2007-07-25 R-HSA-182263 Degradation of MHC I Complex BibTex
2007-07-25 R-HSA-182279 Formation of MHC I:Nef:AP-1:PACS-1 Complex BibTex
2007-07-25 R-HSA-182243 Formation of MHC I:Nef Complex BibTex
2007-07-25 R-HSA-167637 Internalization of Nef:CD28:Clathrin-Coated Pit Adapter Protein Complex BibTex
2007-07-25 R-HSA-167630 Formation of Nef CD28 cytoplasmic tail complex BibTex
2007-07-25 R-HSA-167633 Formation of Nef:Cd28:Clathrin-coated Pit Adapter Protein complex BibTex
2007-07-25 R-HSA-182171 Degradation of CD8 BibTex
2007-07-25 R-HSA-182186 Formation of CD8:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-07-25 R-HSA-182198 Internalization of the CD8:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-07-25 R-HSA-167597 Internalization of the CD4:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-07-25 R-HSA-200879 Formation of a Nef:ARF1:CD4 complex BibTex
2007-07-25 R-HSA-167601 Degradation of CD4 BibTex
2007-07-25 R-HSA-167566 Nef mediated disruption of CD4:Lck Complex BibTex
2007-07-25 R-HSA-167537 Formation of CD4:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-07-25 R-HSA-200908 Nef Binds and activates the Src-family tyrosine kinase Fyn BibTex
2007-07-25 R-HSA-164943 Nef mediated activation of the T-cell receptor BibTex
2007-07-25 R-HSA-200954 Nef Binds and activates the Src-family tyrosine kinase Lck BibTex
2007-07-25 R-HSA-200858 Nef Binds and activates the Src-family tyrosine kinase Hck BibTex
2007-07-14 R-HSA-204008 SEC31:SEC13 and v-SNARE recruitment BibTex
2007-07-14 R-HSA-203973 Vesicle budding BibTex
2007-07-14 R-HSA-5694527 Loss of SAR1B GTPase BibTex
2007-07-14 R-HSA-203977 SAR1 Activation And Membrane Binding BibTex
2007-07-14 R-HSA-203979 Coat Assembly BibTex
2007-01-30 R-HSA-191830 snRNP nuclear import and release BibTex
2007-01-30 R-HSA-191784 snRNA Cap hypermethylation BibTex
2007-01-30 R-HSA-191763 snRNP:Snurportin complex formation BibTex
2007-01-30 R-HSA-191790 Loading and methylation of Sm proteins onto SMN Complexes BibTex
2007-01-30 R-HSA-191825 Nuclear export of snRNA transcripts BibTex
2007-01-30 R-HSA-191786 snRNP complex assembly BibTex
2005-11-14 R-HSA-168297 Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein BibTex
2005-11-14 R-HSA-168317 Recruitment of Karyopherin Beta to form a Trimeric Complex BibTex
2005-11-14 R-HSA-168337 Docking and transport of the RNP:Karyopherin complex through the nuclear pore BibTex
2005-11-14 R-HSA-168310 Release of the RNP into the host cell nucleus BibTex
2005-03-13 R-HSA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC BibTex
2005-01-27 R-HSA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex BibTex
2005-01-27 R-HSA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC BibTex
2005-01-27 R-HSA-158484 Release of the SLBP independent Histone mRNA from the NPC BibTex
2005-01-27 R-HSA-141691 GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex BibTex
2005-01-27 R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex BibTex
2005-01-27 R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex BibTex
2005-01-27 R-HSA-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC BibTex
2005-01-27 R-HSA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC BibTex
2005-01-27 R-HSA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC BibTex
2004-08-25 R-HSA-83586 FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 BibTex
2004-08-25 R-HSA-75146 TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 BibTex
2004-08-25 R-HSA-83656 TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 BibTex
2004-03-13 R-HSA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA BibTex
2004-01-19 R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation BibTex
2004-01-19 R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation BibTex
2004-01-19 R-HSA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA BibTex
2004-01-19 R-HSA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA BibTex
2004-01-19 R-HSA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA BibTex
2003-09-02 R-HSA-73757 Binding of RRN3 to RNA Polymerase I BibTex
2003-07-01 R-HSA-390595 Calcium Binds Troponin-C BibTex
2003-07-01 R-HSA-390598 Myosin Binds ATP BibTex
2003-07-01 R-HSA-390593 ATP Hydrolysis By Myosin BibTex
2003-07-01 R-HSA-390597 Release Of ADP From Myosin BibTex
2003-07-01 R-HSA-445704 Calcium Binds Caldesmon BibTex
2003-07-01 R-HSA-445699 ATP Hydrolysis By Myosin BibTex
2003-07-01 R-HSA-445705 Release Of ADP From Myosin BibTex
2003-07-01 R-HSA-445700 Myosin Binds ATP BibTex
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