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Sevtap Savas

 ORCID
Affiliation
Memorial University of Newfoundland, Faculty of Medicine
Reviewed Reactions (42)
Date Identifier Reaction Reference
2011-11-15 R-HSA-1218833 Binding of ligand-responsive EGFR mutants to chaperoning proteins HSP90 and CDC37 BibTex
2011-11-15 R-HSA-1225947 Binding of SHC1 to p-6Y-EGFR mutants BibTex
2011-11-15 R-HSA-1169421 Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers BibTex
2011-11-15 R-HSA-1220614 Spontaneous dimerization of ligand-responsive EGFR mutants BibTex
2011-11-15 R-HSA-1220613 EGF-induced dimerization of ligand-responsive EGFR mutants BibTex
2011-11-15 R-HSA-1220612 Binding of EGF to ligand-responsive EGFR mutants BibTex
2011-11-15 R-HSA-1248655 Trans-autophosphorylation of EGFRvIII mutant dimers BibTex
2011-11-15 R-HSA-1248002 Ligand-independent dimerization of EGFRvIII mutant BibTex
2011-11-15 R-HSA-1247999 EGFRvIII mutant binds chaperone proteins HSP90 and CDC37. BibTex
2011-11-15 R-HSA-1225950 Binding of GRB2:SOS1 complex to phosphorylated ligand-responsive EGFR mutants BibTex
2011-11-15 R-HSA-1226014 Conversion of PIP2 to PIP3 by PI3K bound to ligand-responsive p-6Y-EGFR mutants BibTex
2011-11-15 R-HSA-1226012 Binding of PI3K to complex of GRB2:GAB1 and ligand-responsive p-6Y-EGFR mutants BibTex
2011-11-15 R-HSA-1226016 Binding of GRB2:GAB1 complex to ligand-responsive p-6Y-EGFR mutants BibTex
2011-11-15 R-HSA-1225951 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants) BibTex
2011-11-15 R-HSA-1225949 Binding of CBL to ligand-responsive p-6Y-EGFR mutants BibTex
2011-11-15 R-HSA-1220610 Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants BibTex
2011-11-15 R-HSA-1247842 Dissociation of phosphorylated PLCG1 from ligand-responsive p-6Y-EGFR mutants BibTex
2011-11-15 R-HSA-1247844 Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants BibTex
2011-11-15 R-HSA-1247841 PLCG1 binds to ligand-responsive p-6Y-EGFR mutants BibTex
2011-11-15 R-HSA-1220611 Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors BibTex
2011-11-15 R-HSA-1225952 Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants BibTex
2011-11-15 R-HSA-1225956 Inefficient ubiquitination of ligand-responsive p-6Y-EGFR mutants by p-Y371-CBL BibTex
2011-11-15 R-HSA-1225960 Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants BibTex
2011-11-15 R-HSA-1225957 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and ligand-responsive p-6Y-EGFR mutants) BibTex
2011-11-15 R-HSA-1225961 Phosphorylated SHC1 in complex with ligand-responsive p-6Y-EGFR mutants recruits GRB2:SOS1 complex BibTex
2011-11-15 R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins BibTex
2011-11-15 R-HSA-5637808 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and p-EGFRvIII) BibTex
2011-11-15 R-HSA-5637798 Phosphorylated SHC1 in complex with p-5Y-EGFRvIII recruits GRB2:SOS1 complex BibTex
2011-11-15 R-HSA-5637796 Phosphorylation of SHC1 by p-5Y-EGFRvIII BibTex
2011-11-15 R-HSA-5638137 EGFRvIII cancer variant does not bind EGF ligand BibTex
2011-11-15 R-HSA-5637766 Binding of SHC1 to p-5Y-EGFRvIII BibTex
2011-11-15 R-HSA-5637764 Binding of GRB2:GAB1 complex to p-EGFRvIII mutant BibTex
2011-11-15 R-HSA-5637765 Binding of PI3K to complex of GRB2:GAB1 and p-EGFRvIII BibTex
2011-11-15 R-HSA-5637794 EGFRvIII does not bind CBL BibTex
2011-11-15 R-HSA-5637795 Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant BibTex
2011-11-15 R-HSA-5637792 PLC-gamma 1 binds to p-EGFRvIII mutant BibTex
2011-11-15 R-HSA-5637806 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with p-EGFRvIII) BibTex
2011-11-15 R-HSA-5637770 Binding of GRB2:SOS1 complex to phosphorylated EGFRvIII BibTex
2011-11-15 R-HSA-5637800 Dissociation of phosphorylated PLC-gamma 1 from p-EGFRvIII mutant BibTex
2011-11-15 R-HSA-5637801 Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII BibTex
2011-11-15 R-HSA-1248677 Inactivation of over-expressed wild type EGFR by Cetuximab recombinant antibody BibTex
2011-11-15 R-HSA-1225978 Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers BibTex
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