Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Carl-Henrik Heldin
ORCID
Are you Carl-Henrik Heldin ? Register or Connect your ORCID
Affiliation
Ludwig Institute for Cancer Research, Uppsala Branch
Expand All
Authored Pathways (1/1)
Date
Identifier
Pathway
Reference
2006-02-02
R-HSA-170834
Signaling by TGF-beta Receptor Complex
BibTex
Show all authored pathways...
Authored Reactions (15/22)
Date
Identifier
Reaction
Reference
2006-02-02
R-HSA-173488
The SMAD2/3:SMAD4 complex transfers to the nucleus
BibTex
2006-02-02
R-HSA-170847
Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4
BibTex
2006-02-02
R-HSA-170850
Phosphorylated SMAD2/3 dissociates from TGFBR
BibTex
2006-02-02
R-HSA-170868
Activated type I receptor phosphorylates SMAD2/3 directly
BibTex
2006-02-02
R-HSA-170835
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3
BibTex
2006-02-02
R-HSA-170843
TGFBR2 phosphorylates TGFBR1
BibTex
2006-02-02
R-HSA-170846
TGFBR2 recruits TGFBR1
BibTex
2006-02-02
R-HSA-170861
Dimeric TGF-beta-1 binds to the receptor
BibTex
2006-02-02
R-HSA-173481
SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling
BibTex
2006-02-02
R-HSA-173545
Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling
BibTex
2006-02-02
R-HSA-177107
Secretion and activation of the latent large complex of TGF-beta-1
BibTex
2006-02-02
R-HSA-170844
Latent TGF-beta-1 is cleaved by FURIN
BibTex
2006-02-02
R-HSA-178178
PP1 dephosphorylates TGFBR1
BibTex
2006-02-02
R-HSA-178189
SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR
BibTex
2006-02-02
R-HSA-173512
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1)
BibTex
Show all authored reactions...
Reviewed Pathways (10/10)
Date
Identifier
Pathway
Reference
2008-11-24
R-HSA-186763
Downstream signal transduction
BibTex
2008-11-24
R-HSA-186797
Signaling by PDGF
BibTex
2008-02-28
R-HSA-177929
Signaling by EGFR
BibTex
2008-02-12
R-HSA-180336
SHC1 events in EGFR signaling
BibTex
2008-02-12
R-HSA-179812
GRB2 events in EGFR signaling
BibTex
2008-02-12
R-HSA-180292
GAB1 signalosome
BibTex
2008-02-12
R-HSA-182971
EGFR downregulation
BibTex
2008-02-12
R-HSA-212718
EGFR interacts with phospholipase C-gamma
BibTex
2007-11-12
R-HSA-201451
Signaling by BMP
BibTex
2006-04-18
R-HSA-170834
Signaling by TGF-beta Receptor Complex
BibTex
Show all reviewed pathways...
Reviewed Reactions (15/96)
Date
Identifier
Reaction
Reference
2008-11-24
R-HSA-186826
GRB2:SOS1 complex binds to the active receptor
BibTex
2008-11-24
R-HSA-186786
Autophosphorylation of PDGF beta receptors
BibTex
2008-11-24
R-HSA-186773
PDGF dimer binds two receptors simultaneously
BibTex
2008-11-24
R-HSA-186785
PDGF-AA clevage by Furin
BibTex
2008-11-24
R-HSA-382053
Translocation of PDGF from ER to Golgi
BibTex
2008-11-24
R-HSA-8865276
PDGF-AB clevage by Furin
BibTex
2008-11-24
R-HSA-8865275
PDGF-BB clevage by Furin
BibTex
2008-11-24
R-HSA-389086
Autophosphorylation of PDGF alpha/beta receptors
BibTex
2008-11-24
R-HSA-389083
Autophosphorylation of PDGF alpha receptors
BibTex
2008-11-24
R-HSA-186780
PI3-kinase binds to the active receptor
BibTex
2008-11-24
R-HSA-186798
GAP binds to PDGF-beta receptors only
BibTex
2008-11-24
R-HSA-382058
Nck binds to the active PDGF receptor
BibTex
2008-11-24
R-HSA-186765
PLC-gamma binds to the active receptor
BibTex
2008-11-24
R-HSA-1524186
Phosphorylation of PLCgamma by PDGFR
BibTex
2008-11-24
R-HSA-186800
PI3K catalyses the phosphorylation of PIP2 to PIP3
BibTex
Show all reviewed reactions...
Please log in again
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text