Search results for HOXA11

Showing 6 results out of 6

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Protein (2 results from a total of 2)

Identifier: R-HSA-9830960
Species: Homo sapiens
Compartment: nucleoplasm
Primary external reference: UniProt: HOXA11: P31270
Identifier: R-MMU-9830926
Species: Mus musculus
Compartment: nucleoplasm
Primary external reference: UniProt: Hoxa11: P31311

Reaction (4 results from a total of 4)

Identifier: R-HSA-9830917
Species: Homo sapiens
Compartment: nucleoplasm
HOXA11 (or HOXC11 or HOXD11), EYA1, and PAX2 physically associate to form a complex which binds upstream of the transcription start site of the SIX2 gene (inferred from mouse homologs). In mice, Hoxa11, Eya1 and Pax2 are individually unable to activate Six2 expression (Gong et al. 2007).
Identifier: R-HSA-9830969
Species: Homo sapiens
Compartment: nucleoplasm
HOXA11 (or HOXC11 or HOXD11) , EYA1, and PAX2 physically interact to form a complex (inferred from mouse homologs) which binds the GDNF gene (inferred from mouse Hox11:Eya1:Pax2 binding the Six2 gene in Gong et al. 2007). The components of the HOX11:EYA1:PAX2 complex synergistically activate expression of GDNF (inferred from the mouse homologs).
Identifier: R-MMU-9830920
Species: Mus musculus
Compartment: nucleoplasm
Hoxa11 (or Hoxc11 or Hoxd11), Eya1, and Pax2 physically associate to form a complex which binds about 450 bp upstream of the transcription start site of the Six2 gene (Gong et al. 2007). The region contains a consensus Hox binding site and a consensus Pax2 binding site (Gong et al. 2007). Hoxa11, Eya1 and Pax2 are individually unable to activate Six2 expression (Gong et al. 2007).
Identifier: R-MMU-9830938
Species: Mus musculus
Compartment: nucleoplasm
Hoxa11 (or Hoxc11 or Hoxd11), Eya1, and Pax2 physically interact to form a complex (Gong et al. 2007) which binds the Gdnf gene (inferred from results with the Six2 gene in Gong et al. 2007). The components of the Hox11:Eya1:Pax2 complex synergistically activate expression of Gdnf (Gong et al. 2007).
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