Search results for HSD3B1

Showing 6 results out of 6

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Protein (1 results from a total of 1)

Identifier: R-HSA-192072
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane
Primary external reference: UniProt: HSD3B1: P14060

Complex (1 results from a total of 1)

Identifier: R-HSA-196351
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane

Reaction (4 results from a total of 4)

Identifier: R-HSA-193052
Species: Homo sapiens
Compartment: cytosol, endoplasmic reticulum membrane
Pregn-5-ene-3,20-dione isomerizes to progesterone. This reaction is catalyzed by the isomerase activity of 3 beta-HSD, associated with the endoplasmic reticulum membrane. The active form of the enzyme is a homodimer. The enzyme occurs in two isoforms that are similar in their biochemical properties but differ in their tissue expression: type I (HSD3B1) is found in placenta and skin, while type II (HSD3B2) is found in the adrenal glands and gonads.
The hormone lutropin (LH) triggers ovulation and development of the corpus luteum, that in turn increases production of progesterone.
Identifier: R-HSA-196350
Species: Homo sapiens
Compartment: cytosol, endoplasmic reticulum membrane
Pregnenolone and NAD+ react to form pregn-5-ene-3,20-dione and NADH + H+. This reaction is catalyzed by the 3 beta-hydroxysteroid activity of 3-beta-hydroxysteroid dehydrogenase/isomerase (HSD3B) enzyme associated with the endoplasmic reticulum membrane. The active form of the enzyme is a homodimer. The enzyme occurs in two isoforms that are similar in their biochemical properties but differ in their tissue expression: type I (HSD3B1) is found in placenta and skin, while type II (HSD3B2) is found in the adrenal glands and gonads.
Identifier: R-HSA-196372
Species: Homo sapiens
Compartment: cytosol, endoplasmic reticulum membrane
17-Hydroxypregnenolone and NAD+ react to form pregn-5-ene-3,20-dione-17-ol and NADH + H+. This reaction is catalyzed by the 3 beta-hydroxysteroid activity of 3-beta-hydroxysteroid dehydrogenase/isomerase (HSD3B) enzyme associated with the endoplasmic reticulum membrane. The active form of the enzyme is a homodimer. The enzyme occurs in two isoforms that are similar in their biochemical properties but differ in their tissue expression: type I (HSD3B1) is found in placenta and skin, while type II (HSD3B2) is found in the adrenal glands and gonads.
Identifier: R-HSA-193961
Species: Homo sapiens
Compartment: cytosol, endoplasmic reticulum membrane
Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone. This reaction is catalyzed by the isomerase activity of 3 beta-HSD, associated with the endoplasmic reticulum membrane. The active form of the enzyme is a homodimer. The enzyme occurs in two isoforms that are similar in their biochemical properties but differ in their tissue expression: type I (HSD3B1) is found in placenta and skin, while type II (HSD3B2) is found in the adrenal glands and gonads.
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