Search results for PPCDC

Showing 2 results out of 2

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Species

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Species

Types

Compartments

Reaction types

Search properties

Protein (1 results from a total of 1)

PPCDC

Identifier: R-HSA-196829
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: PPCDC: Q96CD2

Reaction (1 results from a total of 1)

3xPPCDC:3FMN decarboxylates PPC

Identifier: R-HSA-196840
Species: Homo sapiens
Compartment: cytosol
The decarboxylation of phosphopantothenoylcysteine (PPC) to 4'-phosphopantetheine (PPANT) is carried out by phosphopantothenoylcysteine decarboxylase (PPCDC) (Daugherty et al. 2002). PPCDC is cytosolic and exists as a homotrimer, binding one FMN cofactor per subunit (Strauss et al. 2004). While a second isoform has been inferred from large-scale sequnceing studies, it lacks the protein's FMN-binding domain and would thus appear to be nonfunctional if it is expressed.
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