Search results for SCP2

Showing 11 results out of 11

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Species

Types

Compartments

Reaction types

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Protein (7 results from a total of 7)

Identifier: R-HSA-2046067
Species: Homo sapiens
Compartment: peroxisomal matrix
Primary external reference: UniProt: SCP2: P22307
Identifier: R-HSA-9033130
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: P22307
Identifier: R-HSA-192348
Species: Homo sapiens
Compartment: peroxisomal matrix
Primary external reference: UniProt: SCP2: P22307-1
Identifier: R-HSA-9033486
Species: Homo sapiens
Compartment: peroxisomal matrix
Primary external reference: UniProt: SCP2: P22307
Identifier: R-HSA-9033522
Species: Homo sapiens
Compartment: peroxisomal matrix
Primary external reference: UniProt: P22307
Identifier: R-HSA-912407
Species: Homo sapiens
Compartment: nucleoplasm
Primary external reference: UniProt: SYCP2: Q9BX26
Identifier: R-HSA-535488
Species: Homo sapiens
Compartment: nucleoplasm
Primary external reference: UniProt: CTDSP2: O14595

Reaction (2 results from a total of 2)

Identifier: R-HSA-9033524
Species: Homo sapiens
Compartment: peroxisomal matrix
The trypsin-like serine-type endopeptidase TYSND1 cleaves SCP2 (also known as SCPX) between amino acid residues 424 and 425, yielding SCP2(1-424) and SCP2(425-547) (Okumoto et al. 2011, also inferred from mouse homologs).
Identifier: R-HSA-390224
Species: Homo sapiens
Compartment: peroxisomal matrix
Peroxisomal SCPx (Non-specific lipid transfer protein; SCP2) catalyzes the reaction of 3-ketopristanoyl-CoA and CoASH to form 4,8,12-trimethyltridecanoyl-CoA and propionyl-CoA. Both intact SCPx and an SCPx fragment corresponding to approximately the 430 aminoterminal residues of the protein are catalytically active in vitro; the latter form may predominate in vivo. Consistent with the role of SCPx in the beta-oxidation of branched-chain fatty acids in vitro, mutations in the protein are associated with elevated levels of pristanic acid in the blood in vivo and the development of neurological defects (Ferdinandusse et al. 2000, 2006).

Interactor (1 results from a total of 1)

Identifier: P22307-3
Species: Homo sapiens
Primary external reference: UniProt: P22307-3

DNA Sequence (1 results from a total of 1)

Identifier: R-HSA-5642237
Species: Homo sapiens
Compartment: nucleoplasm
Primary external reference: ENSEMBL: ENSG00000175215
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