Reactome | CHD2:MYOD heterodimer dependent MYOG gene expression

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CHD2:MYOD heterodimer dependent MYOG gene expression Show undefined attributes

authored	[InstanceEdit:9937860] Rothfels, Karen, 2025-02-07
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9943619] Rothfels, Karen, 2025-03-30
dbId	9943620
displayName	CHD2:MYOD heterodimer dependent MYOG gene expression
edited	[InstanceEdit:9937860] Rothfels, Karen, 2025-02-07
eventOf	[Pathway:R-HSA-9943411] CHD1 and CHD2 subfamily - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9677208] MYOG gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9943396] Chd2 interacts with H3.3 to determine myogenic cell fate [LiteratureReference:9677086] Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis [LiteratureReference:9943545] Epigenetic Regulation of Myogenesis: Focus on the Histone Variants
maxDepth	1
modified	[InstanceEdit:9974736] Rothfels, Karen, 2025-11-24
name	CHD2:MYOD heterodimer dependent MYOG gene expression
output	[EntityWithAccessionedSequence:R-HSA-445160] MYOG [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9943571] CHD2 and MYOD heterodimer bind the MYOG gene - Homo sapiens [Reaction:R-HSA-9943614] CHD2-dependent H3.3 deposition at MYOG gene - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9943601] Positive gene expression regulation by 'CHD2:MYOD heterodimer: MYOG gene with H3.3 nucleosome [nucleoplasm]'
regulationReference	[RegulationReference:9943603] Positive gene expression regulation by 'CHD2:MYOD heterodimer: MYOG gene with H3.3 nucleosome [nucleoplasm]' Chd2 interacts with H3.3 to determine myogenic cell fate
releaseDate	2026-03-25
releaseStatus	NEW
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9943620
summation	[Summation:9943621] MYOG gene expression is dependent on MYOD and CHD2, as well ...

Referrals

(hasEvent)

[Pathway:R-HSA-9943411] CHD1 and CHD2 subfamily

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