Reactome | GNB3 [plasma membrane]

GNB3 [plasma membrane]

Stable Identifier

R-HSA-164355

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

G-protein beta 3 (GBB3) subunit

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Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (i) signalling events (Homo sapiens)
      - Opioid Signalling (Homo sapiens)
        
        G-protein activation (Homo sapiens)
        
        The receptor:G-protein complex binds GTP (Homo sapiens)
        
        Opioid:MOR:G-protein complex [plasma membrane] (Homo sapiens)
        
        Heterotrimeric G-protein [plasma membrane] (Homo sapiens)
        
        G-protein beta subunit [plasma membrane] (Homo sapiens)
        
        GNB3 [plasma membrane] (Homo sapiens)
        
        The receptor:G-protein complex releases GDP (Homo sapiens)
        
        Opioid:MOR:G-protein complex [plasma membrane] (Homo sapiens)
        
        Heterotrimeric G-protein [plasma membrane] (Homo sapiens)
        
        G-protein beta subunit [plasma membrane] (Homo sapiens)
        
        GNB3 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P16520 GNB3

Gene Names

GNB3

Chain

chain:1-340

Reference Genes

BioGPS Gene:2784 GNB3

COSMIC (genes):GNB3 GNB3

CTD Gene:2784 GNB3

dbSNP Gene:2784 GNB3

ENSEMBL:ENSG00000111664 GNB3

ENSEMBL_homo_sapiens_GENE:ENSG00000111664.11 GNB3

HGNC:4400 GNB3

KEGG Gene (Homo sapiens):2784 GNB3

Monarch:2784 GNB3

NCBI Gene:2784 GNB3

OMIM:139130 GNB3

UCSC:P16520 GNB3

Reference Transcript

Other Identifiers

11754570_a_at

165_g_at

16747481

206047_PM_at

206047_at

225_at

2784

3402876

3402877

3402879

3402880

3402882

3402884

3402885

3402886

3402887

3402888

3402891

3402892

3402893

3402894

40351_at

7953469

A_14_P131417

GE80462

GO:0003013

GO:0003824

GO:0003924

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005829

GO:0005834

GO:0005886

GO:0005975

GO:0006629

GO:0006884

GO:0007165

GO:0007186

GO:0008092

GO:0008217

GO:0010468

GO:0010906

GO:0016787

GO:0023052

GO:0030154

GO:0030159

GO:0030425

GO:0030507

GO:0032350

GO:0043226

GO:0044297

GO:0045598

GO:0051020

GO:0060090

GO:0070062

GO:0090181

GO:0090207

GO:1903725

HMNXSV003001677

ILMN_2115336

M31328_at

PH_hs_0004145

TC12000094.hg

TC12002206.hg

g4504052_3p_at

g4504052_3p_x_at

Participates

as a candidate of

G-protein beta subunit [plasma membrane] (Homo sapiens)

as a member of

GNB1,3 [plasma membrane] (Homo sapiens)

Other forms of this molecule

Unfolded GNB3 [cytosol]

Partially folded GNB3 [cytosol]

GNB3 [cytosol]

Inferred To

gnb3 [plasma membrane] (Xenopus tropicalis)

GNB3 [plasma membrane] (Bos taurus)

GNB3 [plasma membrane] (Canis familiaris)

GNB3 [plasma membrane] (Gallus gallus)

GNB3 [plasma membrane] (Sus scrofa)

Gbeta13F [plasma membrane] (Drosophila melanogaster)

gnb3a [plasma membrane] (Danio rerio)

Homologues of GNB3 [plasma membrane] (Drosophila melanogaster)

gpb-1 [plasma membrane] (Caenorhabditis elegans)

Gbeta76C [plasma membrane] (Drosophila melanogaster)

Gnb3 [plasma membrane] (Mus musculus)

Gnb3 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001284500.1, NP_002066.1

OpenTargets

ENSG00000111664

HPA

ENSG00000111664-GNB3

GeneCards

P16520

Ensembl

ENSG00000111664, ENSP00000229264, ENST00000229264

PRO

P16520

Pharos - Targets

P16520

Orphanet

25858

HMDB Protein

HMDBP08400

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