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ASB5 [cytosol]
Stable Identifier
R-HSA-975420
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ankyrin repeat and SOCS box protein 5, ASB5_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Neddylation (Homo sapiens)
AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase [cytosol] (Homo sapiens)
CUL5-box protein [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
NEDD8-CRL5 E3 ligase [cytosol] (Homo sapiens)
CUL5-box protein [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Homo sapiens)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Homo sapiens)
CRL E3 ubiquitin ligases [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase [cytosol] (Homo sapiens)
CUL5-box protein [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
CRL E3 ubiquitin ligases [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase [cytosol] (Homo sapiens)
CUL5-box protein [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Homo sapiens)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Homo sapiens)
CRL E3 ubiquitin ligases [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase [cytosol] (Homo sapiens)
CUL5-box protein [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase [cytosol] (Homo sapiens)
CUL5-box protein [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Homo sapiens)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase [cytosol] (Homo sapiens)
CUL5-box protein [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
NEDD8-CRL5 E3 ligase [cytosol] (Homo sapiens)
CUL5-box protein [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Homo sapiens)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase [cytosol] (Homo sapiens)
CUL5-box protein [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase [cytosol] (Homo sapiens)
CUL5-box protein [cytosol] (Homo sapiens)
ASB5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WWX0 ASB5
Gene Names
ASB5
Chain
chain:1-329
Reference Genes
BioGPS Gene:140458 ASB5
COSMIC - genes:ASB5 ASB5
CTD Gene:140458 ASB5
dbSNP Gene:140458 ASB5
ENSEMBL:ENSG00000164122 ASB5
HGNC:17180 ASB5
KEGG:hsa:140458 ASB5
Monarch:140458 ASB5
NCBI Gene:140458 ASB5
OMIM:615050 ASB5
UCSC:Q8WWX0 ASB5
Reference Transcript
RefSeq:XM_054348970.1 ASB5
RefSeq:NM_080874.4 ASB5
RefSeq:XM_011531617.4 ASB5
RefSeq:XM_005262759.2 ASB5
RefSeq:XM_054348969.1 ASB5
Other Identifiers
11729323_a_at
11729324_s_at
140458
16981706
235503_PM_at
235503_at
2794705
2794706
2794707
2794708
2794709
2794710
2794711
2794712
2794713
2794714
2794715
2794716
2794718
2794721
2794722
2794723
2794724
2794725
2794727
2794728
2794729
2794730
2794733
2794734
2794735
60226_at
8103812
A_23_P144326
A_24_P97559
GE496014
GO:0005515
GO:0005829
GO:0016020
GO:0016567
GO:0035556
GO:0045732
HMNXSV003026410
Hs.99569.0.A1_3p_at
ILMN_1711269
ILMN_2126055
PH_hs_0017066
TC04001762.hg
Participates
as a member of
CUL5-box protein [cytosol] (Homo sapiens)
ASB family [cytosol] (Homo sapiens)
Inferred To
ASB5 [cytosol]
(Bos taurus)
ASB5 [cytosol]
(Canis familiaris)
ASB5 [cytosol]
(Gallus gallus)
ASB5 [cytosol]
(Sus scrofa)
asb5 [cytosol]
(Xenopus tropicalis)
asb5b [cytosol]
(Danio rerio)
Asb5 [cytosol]
(Mus musculus)
Asb5 [cytosol]
(Rattus norvegicus)
swah-1 [cytosol]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_543150.1
,
XP_054204945.1
,
XP_054204944.1
,
XP_005262816.1
,
XP_011529919.1
ENSEMBL
ENSP00000296525
,
ENSP00000422877
,
ENST00000512254
,
ENSG00000164122
,
ENST00000296525
OpenTargets
ENSG00000164122
GeneCards
ASB5
HPA
ENSG00000164122-ASB5
PRO
Q8WWX0
Pharos - Targets
Q8WWX0
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