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TPH2 [cytosol]
Stable Identifier
R-HSA-976257
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of amine-derived hormones (Homo sapiens)
Serotonin and melatonin biosynthesis (Homo sapiens)
Tryptophan is hydroxylated (Homo sapiens)
TPH:Fe++ [cytosol] (Homo sapiens)
TPH [cytosol] (Homo sapiens)
TPH2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IWU9 TPH2
Gene Names
TPH2, NTPH
Chain
chain:1-490
Reference Genes
BioGPS Gene:121278 TPH2
COSMIC - genes:TPH2 TPH2
CTD Gene:121278 TPH2
dbSNP Gene:121278 TPH2
ENSEMBL:ENSG00000139287 TPH2
HGNC:20692 TPH2
KEGG:hsa:121278 TPH2
Monarch:121278 TPH2
NCBI Gene:121278 TPH2
OMIM:607478 TPH2
UCSC:Q8IWU9 TPH2
Reference Transcript
RefSeq:NM_173353.3 TPH2
Other Identifiers
11738464_at
11738465_at
121278
1555332_PM_at
1555332_at
3422387
3422388
3422389
3422392
3422393
3422394
3422395
3422401
3422409
3422410
3422411
3422412
3422417
3422418
3422421
3422425
3422429
3422430
3422431
3422432
3422433
3422434
3422435
3422436
3422437
3422438
3422440
3422441
3422442
3422443
3422444
3422447
3422448
3422459
7957205
A_14_P112767
A_14_P115870
A_14_P132020
A_23_P316543
A_24_P129834
A_24_P401787
GE518862
GO:0004497
GO:0004510
GO:0005506
GO:0005829
GO:0006520
GO:0009072
GO:0016491
GO:0016714
GO:0042427
GO:0043005
GO:0046872
HMNXSV003014550
Hs2.376337.2.S1_3p_at
ILMN_1734352
PH_hs_0018312
PH_hs_0039066
TC12000629.hg
Participates
as a member of
TPH [cytosol] (Homo sapiens)
Inferred To
TPH2 [cytosol]
(Bos taurus)
TPH2 [cytosol]
(Caenorhabditis elegans)
TPH2 [cytosol]
(Canis familiaris)
TPH2 [cytosol]
(Dictyostelium discoideum)
TPH2 [cytosol]
(Drosophila melanogaster)
TPH2 [cytosol]
(Gallus gallus)
TPH2 [cytosol]
(Mus musculus)
TPH2 [cytosol]
(Rattus norvegicus)
TPH2 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_775489.2
Guide to Pharmacology - Targets
1242
ENSEMBL
ENSG00000139287
,
ENST00000333850
,
ENSP00000329093
OpenTargets
ENSG00000139287
ZINC - Substances
TPH2_HUMAN
ZINC target
Q8IWU9
PRO
Q8IWU9
GlyGen
Q8IWU9
PDB
7QRI
,
7WIY
,
9HB7
,
4V06
,
9HB8
GeneCards
TPH2
HPA
ENSG00000139287-TPH2
Pharos - Targets
Q8IWU9
ZINC - Predictions - Purchasable
TPH2_HUMAN
HMDB Protein
HMDBP00471
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