Reactome | UniProt:P05067-PRO

UniProt:P05067-PRO_0000000092 APP

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, A4, AD1, ABPP, PreA4, Protease nexin-II, APPI, Amyloid precursor protein, Amyloid-beta A4 protein, Alzheimer disease amyloid A4 protein homolog, Amyloid-beta (A4) precursor protein

List of interactors in Reactome

Interactors (8)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P10636	3	MAPT [cytosol] (R-HSA-201574) MAPT(2-421) [cytosol] (R-HSA-350628) MAPT(422-758) [cytosol] (R-HSA-350642)	0.71	5
P04156	1	PRNP [plasma membrane] (R-HSA-375060)	0.667	3
28815	1	HS [extracellular region] (R-ALL-190915)	0.623	3
P08253	5	MMP2(110-660) [extracellular region] (R-HSA-381456) MMP2(30-66) [extracellular region] (R-HSA-1604347) MMP2(30-660) [extracellular region] (R-HSA-1604364) MMP2(67-109) [extracellular region] (R-HSA-1604371) MMP2(67-660) [extracellular region] (R-HSA-1604345)	0.623	4
Q9NZC2	1	TREM2 [plasma membrane] (R-HSA-197664)	0.611	4
O60602	1	TLR5 [plasma membrane] (R-HSA-168013)	0.558	3
Q99NH8	1	TREM2 [plasma membrane] (R-MMU-197664)	0.544	2
Q9BYF1	4	ACE2 [endocytic vesicle membrane] (R-HSA-9698958) ACE2 [endoplasmic reticulum lumen] (R-HSA-9683474) glycosylated-ACE2 [endocytic vesicle membrane] (R-HSA-9686721) glycosylated-ACE2 [plasma membrane] (R-HSA-9683480)	0.489	3

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