Marija Orlic-Milacic

Ontario Institute for Cancer Research
Authored Pathways (15/396)
Date Identifier Pathway Reference
2022-01-26 R-HSA-9763198 Impaired BRCA2 binding to SEM1 (DSS1) BibTex
2021-09-21 R-HSA-9754119 Drug-mediated inhibition of CDK4/CDK6 activity BibTex
2021-06-15 R-HSA-9734091 Drug-mediated inhibition of MET activation BibTex
2021-06-14 R-HSA-9734009 Defective Intrinsic Pathway for Apoptosis BibTex
2021-05-28 R-HSA-9729902 Reversible DNA damage induced by alkylating chemotherapeutic drugs BibTex
2021-05-11 R-HSA-9730737 Alkylating DNA damage induced by chemotherapeutic drugs BibTex
2021-04-07 R-HSA-9723907 Loss of Function of TP53 in Cancer BibTex
2021-04-07 R-HSA-9723905 Loss of function of TP53 in cancer due to loss of tetramerization ability BibTex
2021-02-01 R-HSA-9750126 Drug-induced formation of DNA interstrand crosslinks BibTex
2020-12-11 R-HSA-9701190 Defective homologous recombination repair (HRR) due to BRCA2 loss of function BibTex
2020-12-11 R-HSA-9709275 Impaired BRCA2 translocation to the nucleus BibTex
2020-12-11 R-HSA-9709603 Impaired BRCA2 binding to PALB2 BibTex
2020-12-11 R-HSA-9709570 Impaired BRCA2 binding to RAD51 BibTex
2020-11-11 R-HSA-9675136 Diseases of DNA Double-Strand Break Repair BibTex
2020-10-15 R-HSA-9701192 Defective HDR through Homologous Recombination (HRR) due to BRCA1 loss-of-function BibTex
Authored Reactions (15/2,808)
Date Identifier Reaction Reference
2022-01-26 R-HSA-9763200 BRCA2 mutants do not bind SEM1 (DSS1) BibTex
2022-01-26 R-HSA-9763137 BRCA2 binds SEM1 (DSS1) BibTex
2021-09-21 R-HSA-9754130 CDK4 inhibitors bind CDK4 BibTex
2021-09-21 R-HSA-9754129 CDK6 inhibitors bind CDK6 BibTex
2021-07-15 R-HSA-9736953 FURIN translocates to the plasma membrane BibTex
2021-06-15 R-HSA-9734070 Anti-MET recombinant therapeutic antibodies bind MET BibTex
2021-06-15 R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET BibTex
2021-06-01 R-HSA-9733216 COL1A2 gene expression is stimulated by p-2S-SMAD3:p-2S-SMAD3:SMAD4 BibTex
2021-06-01 R-HSA-9733247 YBX1 binds COL1A2 gene promoter BibTex
2021-06-01 R-HSA-9733203 FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4 BibTex
2021-06-01 R-HSA-9733207 p-2S-SMAD3:p-2S-SMAD3:SMAD4 forms a complex with SP1 and EP300 at the COL1A2 gene promoter BibTex
2021-05-28 R-MMU-9749883 Temozolomide produces DNA damage in the form of O6-methylguanine in mouse dsDNA BibTex
2021-05-28 R-HSA-9732692 Triazenes produce DNA damage in the form of O6-methylguanine BibTex
2021-05-13 R-HSA-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 BibTex
2021-05-12 R-HSA-9730967 STAT1 stimulates SMAD7 gene transcription BibTex
Reviewed Pathways (1/1)
Date Identifier Pathway Reference
2020-01-23 R-HSA-9675108 Nervous system development BibTex
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