|
R-HSA-5649702
|
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway
|
|
R-HSA-8854518
|
AURKA Activation by TPX2
|
|
R-HSA-2122948
|
Activated NOTCH1 Transmits Signal to the Nucleus
|
|
R-HSA-9032845
|
Activated NTRK2 signals through CDK5
|
|
R-HSA-9028731
|
Activated NTRK2 signals through FRS2 and FRS3
|
|
R-HSA-9032500
|
Activated NTRK2 signals through FYN
|
|
R-HSA-9028335
|
Activated NTRK2 signals through PI3K
|
|
R-HSA-9026527
|
Activated NTRK2 signals through PLCG1
|
|
R-HSA-9026519
|
Activated NTRK2 signals through RAS
|
|
R-HSA-9603381
|
Activated NTRK3 signals through PI3K
|
|
R-HSA-9034793
|
Activated NTRK3 signals through PLCG1
|
|
R-HSA-9034864
|
Activated NTRK3 signals through RAS
|
|
R-HSA-5625886
|
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
|
|
R-HSA-2980767
|
Activation of NIMA Kinases NEK9, NEK6, NEK7
|
|
R-HSA-8866907
|
Activation of the TFAP2 (AP-2) family of transcription factors
|
|
R-HSA-9024909
|
BDNF activates NTRK2 (TRKB) signaling
|
|
R-HSA-73884
|
Base Excision Repair
|
|
R-HSA-2559583
|
Cellular Senescence
|
|
R-HSA-2993913
|
Clearance of Nuclear Envelope Membranes from Chromatin
|
|
R-HSA-2470946
|
Cohesin Loading onto Chromatin
|
|
R-HSA-8948700
|
Competing endogenous RNAs (ceRNAs) regulate PTEN translation
|
|
R-HSA-2514853
|
Condensation of Prometaphase Chromosomes
|
|
R-HSA-2299718
|
Condensation of Prophase Chromosomes
|
|
R-HSA-5674400
|
Constitutive Signaling by AKT1 E17K in Cancer
|
|
R-HSA-2219530
|
Constitutive Signaling by Aberrant PI3K in Cancer
|
|
R-HSA-5637810
|
Constitutive Signaling by EGFRvIII
|
|
R-HSA-1236382
|
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
|
|
R-HSA-2691232
|
Constitutive Signaling by NOTCH1 HD Domain Mutants
|
|
R-HSA-2894862
|
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
|
|
R-HSA-2644606
|
Constitutive Signaling by NOTCH1 PEST Domain Mutants
|
|
R-HSA-2660826
|
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
|
|
R-HSA-6814122
|
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
|
|
R-HSA-73893
|
DNA Damage Bypass
|
|
R-HSA-5696394
|
DNA Damage Recognition in GG-NER
|
|
R-HSA-2559586
|
DNA Damage/Telomere Stress Induced Senescence
|
|
R-HSA-5693606
|
DNA Double Strand Break Response
|
|
R-HSA-5693532
|
DNA Double-Strand Break Repair
|
|
R-HSA-4419969
|
Depolymerisation of the Nuclear Lamina
|
|
R-HSA-8863795
|
Downregulation of ERBB2 signaling
|
|
R-HSA-1358803
|
Downregulation of ERBB2:ERBB3 signaling
|
|
R-HSA-1253288
|
Downregulation of ERBB4 signaling
|
|
R-HSA-2173795
|
Downregulation of SMAD2/3:SMAD4 transcriptional activity
|
|
R-HSA-2173788
|
Downregulation of TGF-beta receptor signaling
|
|
R-HSA-5696400
|
Dual Incision in GG-NER
|
|
R-HSA-6782135
|
Dual incision in TC-NER
|
|
R-HSA-8847993
|
ERBB2 Activates PTK6 Signaling
|
|
R-HSA-6785631
|
ERBB2 Regulates Cell Motility
|
|
R-HSA-2468052
|
Establishment of Sister Chromatid Cohesion
|
|
R-HSA-9036866
|
Expression and Processing of Neurotrophins
|
|
R-HSA-8854050
|
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
|
|
R-HSA-2644605
|
FBXW7 Mutants and NOTCH1 in Cancer
|
|
R-HSA-6783310
|
Fanconi Anemia Pathway
|
|
R-HSA-5696395
|
Formation of Incision Complex in GG-NER
|
|
R-HSA-2559584
|
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
|
|
R-HSA-6781823
|
Formation of TC-NER Pre-Incision Complex
|
|
R-HSA-1538133
|
G0 and Early G1
|
|
R-HSA-1963640
|
GRB2 events in ERBB2 signaling
|
|
R-HSA-1306955
|
GRB7 events in ERBB2 signaling
|
|
R-HSA-5696397
|
Gap-filling DNA repair synthesis and ligation in GG-NER
|
|
R-HSA-6782210
|
Gap-filling DNA repair synthesis and ligation in TC-NER
|
|
R-HSA-5696399
|
Global Genome Nucleotide Excision Repair (GG-NER)
|
|
R-HSA-5685942
|
HDR through Homologous Recombination (HRR)
|
|
R-HSA-5693567
|
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
|
|
R-HSA-5685939
|
HDR through MMEJ (alt-NHEJ)
|
|
R-HSA-5685938
|
HDR through Single Strand Annealing (SSA)
|
|
R-HSA-5693579
|
Homologous DNA Pairing and Strand Exchange
|
|
R-HSA-5693538
|
Homology Directed Repair
|
|
R-HSA-5638303
|
Inhibition of Signaling by Overexpressed EGFR
|
|
R-HSA-2995383
|
Initiation of Nuclear Envelope Reformation
|
|
R-HSA-8876493
|
InlA-mediated entry of Listeria monocytogenes into host cells
|
|
R-HSA-8875360
|
InlB-mediated entry of Listeria monocytogenes into host cell
|
|
R-HSA-8854521
|
Interaction between PHLDA1 and AURKA
|
|
R-HSA-8876384
|
Listeria monocytogenes entry into host cells
|
|
R-HSA-2644607
|
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
|
|
R-HSA-3304349
|
Loss of Function of SMAD2/3 in Cancer
|
|
R-HSA-3304347
|
Loss of Function of SMAD4 in Cancer
|
|
R-HSA-3656534
|
Loss of Function of TGFBR1 in Cancer
|
|
R-HSA-3642278
|
Loss of Function of TGFBR2 in Cancer
|
|
R-HSA-2465910
|
MASTL Facilitates Mitotic Progression
|
|
R-HSA-6806942
|
MET Receptor Activation
|
|
R-HSA-8851907
|
MET activates PI3K/AKT signaling
|
|
R-HSA-8874081
|
MET activates PTK2 signaling
|
|
R-HSA-8865999
|
MET activates PTPN11
|
|
R-HSA-8875555
|
MET activates RAP1 and RAC1
|
|
R-HSA-8851805
|
MET activates RAS signaling
|
|
R-HSA-8875791
|
MET activates STAT3
|
|
R-HSA-8875513
|
MET interacts with TNS proteins
|
|
R-HSA-8875878
|
MET promotes cell motility
|
|
R-HSA-8875656
|
MET receptor recycling
|
|
R-HSA-453279
|
Mitotic G1-G1/S phases
|
|
R-HSA-2122947
|
NOTCH1 Intracellular Domain Regulates Transcription
|
|
R-HSA-2979096
|
NOTCH2 Activation and Transmission of Signal to the Nucleus
|
|
R-HSA-2197563
|
NOTCH2 intracellular domain regulates transcription
|
|
R-HSA-9013507
|
NOTCH3 Activation and Transmission of Signal to the Nucleus
|
|
R-HSA-9013508
|
NOTCH3 Intracellular Domain Regulates Transcription
|
|
R-HSA-9013700
|
NOTCH4 Activation and Transmission of Signal to the Nucleus
|
|
R-HSA-9013695
|
NOTCH4 Intracellular Domain Regulates Transcription
|
|
R-HSA-9025046
|
NTF3 activates NTRK2 (TRKB) signaling
|
|
R-HSA-9034013
|
NTF3 activates NTRK3 signaling
|
|
R-HSA-9026357
|
NTF4 activates NTRK2 (TRKB) signaling
|
|
R-HSA-9032759
|
NTRK2 activates RAC1
|
|
R-HSA-9603505
|
NTRK3 as a dependence receptor
|
|
R-HSA-6807004
|
Negative regulation of MET activity
|
|
R-HSA-9604323
|
Negative regulation of NOTCH4 signaling
|
|
R-HSA-8866904
|
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
|
|
R-HSA-8863678
|
Neurodegenerative Diseases
|
|
R-HSA-9017802
|
Noncanonical activation of NOTCH3
|
|
R-HSA-2980766
|
Nuclear Envelope Breakdown
|
|
R-HSA-2995410
|
Nuclear Envelope Reassembly
|
|
R-HSA-3301854
|
Nuclear Pore Complex (NPC) Disassembly
|
|
R-HSA-1251985
|
Nuclear signaling by ERBB4
|
|
R-HSA-5696398
|
Nucleotide Excision Repair
|
|
R-HSA-2559585
|
Oncogene Induced Senescence
|
|
R-HSA-2559580
|
Oxidative Stress Induced Senescence
|
|
R-HSA-5651801
|
PCNA-Dependent Long Patch Base Excision Repair
|
|
R-HSA-1963642
|
PI3K events in ERBB2 signaling
|
|
R-HSA-1250342
|
PI3K events in ERBB4 signaling
|
|
R-HSA-2219528
|
PI3K/AKT Signaling in Cancer
|
|
R-HSA-6811555
|
PI5P Regulates TP53 Acetylation
|
|
R-HSA-6811558
|
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
|
|
R-HSA-1251932
|
PLCG1 events in ERBB2 signaling
|
|
R-HSA-5674404
|
PTEN Loss of Function in Cancer
|
|
R-HSA-6807070
|
PTEN Regulation
|
|
R-HSA-8849474
|
PTK6 Activates STAT3
|
|
R-HSA-8849472
|
PTK6 Down-Regulation
|
|
R-HSA-8849473
|
PTK6 Expression
|
|
R-HSA-8849470
|
PTK6 Regulates Cell Cycle
|
|
R-HSA-8849468
|
PTK6 Regulates Proteins Involved in RNA Processing
|
|
R-HSA-8849471
|
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
|
|
R-HSA-8849469
|
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
|
|
R-HSA-8857538
|
PTK6 promotes HIF1A stabilization
|
|
R-HSA-8850843
|
Phosphate bond hydrolysis by NTPDase proteins
|
|
R-HSA-1912422
|
Pre-NOTCH Expression and Processing
|
|
R-HSA-1912399
|
Pre-NOTCH Processing in the Endoplasmic Reticulum
|
|
R-HSA-1912408
|
Pre-NOTCH Transcription and Translation
|
|
R-HSA-5693616
|
Presynaptic phase of homologous DNA pairing and strand exchange
|
|
R-HSA-5693607
|
Processing of DNA double-strand break ends
|
|
R-HSA-195258
|
RHO GTPase Effectors
|
|
R-HSA-5663220
|
RHO GTPases Activate Formins
|
|
R-HSA-5668599
|
RHO GTPases Activate NADPH Oxidases
|
|
R-HSA-5627117
|
RHO GTPases Activate ROCKs
|
|
R-HSA-5666185
|
RHO GTPases Activate Rhotekin and Rhophilins
|
|
R-HSA-5663213
|
RHO GTPases Activate WASPs and WAVEs
|
|
R-HSA-5625900
|
RHO GTPases activate CIT
|
|
R-HSA-5626467
|
RHO GTPases activate IQGAPs
|
|
R-HSA-5625970
|
RHO GTPases activate KTN1
|
|
R-HSA-5627123
|
RHO GTPases activate PAKs
|
|
R-HSA-5625740
|
RHO GTPases activate PKNs
|
|
R-HSA-5627083
|
RHO GTPases regulate CFTR trafficking
|
|
R-HSA-9010642
|
ROBO receptors bind AKAP5
|
|
R-HSA-8877330
|
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
|
|
R-HSA-8939243
|
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
|
|
R-HSA-8931987
|
RUNX1 regulates estrogen receptor mediated transcription
|
|
R-HSA-8935964
|
RUNX1 regulates expression of components of tight junctions
|
|
R-HSA-8936459
|
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
|
|
R-HSA-8939245
|
RUNX1 regulates transcription of genes involved in BCR signaling
|
|
R-HSA-8939256
|
RUNX1 regulates transcription of genes involved in WNT signaling
|
|
R-HSA-8939236
|
RUNX1 regulates transcription of genes involved in differentiation of HSCs
|
|
R-HSA-8939242
|
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
|
|
R-HSA-8939246
|
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
|
|
R-HSA-8939247
|
RUNX1 regulates transcription of genes involved in interleukin signaling
|
|
R-HSA-8941326
|
RUNX2 regulates bone development
|
|
R-HSA-8941284
|
RUNX2 regulates chondrocyte maturation
|
|
R-HSA-8941332
|
RUNX2 regulates genes involved in cell migration
|
|
R-HSA-8941333
|
RUNX2 regulates genes involved in differentiation of myeloid cells
|
|
R-HSA-8940973
|
RUNX2 regulates osteoblast differentiation
|
|
R-HSA-8949275
|
RUNX3 Regulates Immune Response and Cell Migration
|
|
R-HSA-8952158
|
RUNX3 regulates BCL2L11 (BIM) transcription
|
|
R-HSA-8941855
|
RUNX3 regulates CDKN1A transcription
|
|
R-HSA-8941856
|
RUNX3 regulates NOTCH signaling
|
|
R-HSA-8951911
|
RUNX3 regulates RUNX1-mediated transcription
|
|
R-HSA-8951430
|
RUNX3 regulates WNT signaling
|
|
R-HSA-8951671
|
RUNX3 regulates YAP1-mediated transcription
|
|
R-HSA-8951936
|
RUNX3 regulates p14-ARF
|
|
R-HSA-110314
|
Recognition of DNA damage by PCNA-containing replication complex
|
|
R-HSA-2565942
|
Regulation of PLK1 Activity at G2/M Transition
|
|
R-HSA-8943724
|
Regulation of PTEN gene transcription
|
|
R-HSA-8948747
|
Regulation of PTEN localization
|
|
R-HSA-8943723
|
Regulation of PTEN mRNA translation
|
|
R-HSA-8948751
|
Regulation of PTEN stability and activity
|
|
R-HSA-8934593
|
Regulation of RUNX1 Expression and Activity
|
|
R-HSA-8939902
|
Regulation of RUNX2 expression and activity
|
|
R-HSA-8941858
|
Regulation of RUNX3 expression and activity
|
|
R-HSA-5633007
|
Regulation of TP53 Activity
|
|
R-HSA-6804758
|
Regulation of TP53 Activity through Acetylation
|
|
R-HSA-6804759
|
Regulation of TP53 Activity through Association with Co-factors
|
|
R-HSA-6804760
|
Regulation of TP53 Activity through Methylation
|
|
R-HSA-6804756
|
Regulation of TP53 Activity through Phosphorylation
|
|
R-HSA-6804757
|
Regulation of TP53 Degradation
|
|
R-HSA-6804754
|
Regulation of TP53 Expression
|
|
R-HSA-6806003
|
Regulation of TP53 Expression and Degradation
|
|
R-HSA-8985801
|
Regulation of cortical dendrite branching
|
|
R-HSA-9010553
|
Regulation of expression of SLITs and ROBOs
|
|
R-HSA-5693537
|
Resolution of D-Loop Structures
|
|
R-HSA-5693568
|
Resolution of D-loop Structures through Holliday Junction Intermediates
|
|
R-HSA-2500257
|
Resolution of Sister Chromatid Cohesion
|
|
R-HSA-1250196
|
SHC1 events in ERBB2 signaling
|
|
R-HSA-1250347
|
SHC1 events in ERBB4 signaling
|
|
R-HSA-8985586
|
SLIT2:ROBO1 increases RHOA activity
|
|
R-HSA-3315487
|
SMAD2/3 MH2 Domain Mutants in Cancer
|
|
R-HSA-3304356
|
SMAD2/3 Phosphorylation Motif Mutants in Cancer
|
|
R-HSA-2173796
|
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
|
|
R-HSA-3311021
|
SMAD4 MH2 Domain Mutants in Cancer
|
|
R-HSA-2559582
|
Senescence-Associated Secretory Phenotype (SASP)
|
|
R-HSA-2467813
|
Separation of Sister Chromatids
|
|
R-HSA-162582
|
Signal Transduction
|
|
R-HSA-1643713
|
Signaling by EGFR in Cancer
|
|
R-HSA-5637812
|
Signaling by EGFRvIII in Cancer
|
|
R-HSA-1227986
|
Signaling by ERBB2
|
|
R-HSA-1236394
|
Signaling by ERBB4
|
|
R-HSA-5637815
|
Signaling by Ligand-Responsive EGFR Variants in Cancer
|
|
R-HSA-6806834
|
Signaling by MET
|
|
R-HSA-1980143
|
Signaling by NOTCH1
|
|
R-HSA-2691230
|
Signaling by NOTCH1 HD Domain Mutants in Cancer
|
|
R-HSA-2894858
|
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
|
|
R-HSA-2644602
|
Signaling by NOTCH1 PEST Domain Mutants in Cancer
|
|
R-HSA-2644603
|
Signaling by NOTCH1 in Cancer
|
|
R-HSA-2660825
|
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
|
|
R-HSA-9012852
|
Signaling by NOTCH3
|
|
R-HSA-9013694
|
Signaling by NOTCH4
|
|
R-HSA-9006115
|
Signaling by NTRK2 (TRKB)
|
|
R-HSA-9034015
|
Signaling by NTRK3 (TRKC)
|
|
R-HSA-5638302
|
Signaling by Overexpressed Wild-Type EGFR in Cancer
|
|
R-HSA-8848021
|
Signaling by PTK6
|
|
R-HSA-3304351
|
Signaling by TGF-beta Receptor Complex in Cancer
|
|
R-HSA-8847453
|
Synthesis of PIPs in the nucleus
|
|
R-HSA-8866911
|
TFAP2 (AP-2) family regulates transcription of cell cycle factors
|
|
R-HSA-8866910
|
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
|
|
R-HSA-8866906
|
TFAP2 (AP-2) family regulates transcription of other transcription factors
|
|
R-HSA-8869496
|
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
|
|
R-HSA-2173789
|
TGF-beta receptor signaling activates SMADs
|
|
R-HSA-2173791
|
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
|
|
R-HSA-3656532
|
TGFBR1 KD Mutants in Cancer
|
|
R-HSA-3656535
|
TGFBR1 LBD Mutants in Cancer
|
|
R-HSA-3645790
|
TGFBR2 Kinase Domain Mutants in Cancer
|
|
R-HSA-3642279
|
TGFBR2 MSI Frameshift Mutants in Cancer
|
|
R-HSA-5628897
|
TP53 Regulates Metabolic Genes
|
|
R-HSA-6803207
|
TP53 Regulates Transcription of Caspase Activators and Caspases
|
|
R-HSA-6791312
|
TP53 Regulates Transcription of Cell Cycle Genes
|
|
R-HSA-5633008
|
TP53 Regulates Transcription of Cell Death Genes
|
|
R-HSA-6796648
|
TP53 Regulates Transcription of DNA Repair Genes
|
|
R-HSA-6803211
|
TP53 Regulates Transcription of Death Receptors and Ligands
|
|
R-HSA-6803204
|
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
|
|
R-HSA-6804116
|
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
|
|
R-HSA-6804114
|
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
|
|
R-HSA-6804115
|
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
|
|
R-HSA-6803205
|
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
|
|
R-HSA-5656169
|
Termination of translesion DNA synthesis
|
|
R-HSA-8852276
|
The role of GTSE1 in G2/M progression after G2 checkpoint
|
|
R-HSA-1362277
|
Transcription of E2F targets under negative control by DREAM complex
|
|
R-HSA-1362300
|
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
|
|
R-HSA-6781827
|
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
|
|
R-HSA-8953750
|
Transcriptional Regulation by E2F6
|
|
R-HSA-3700989
|
Transcriptional Regulation by TP53
|
|
R-HSA-2173793
|
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
|
|
R-HSA-8878171
|
Transcriptional regulation by RUNX1
|
|
R-HSA-8878166
|
Transcriptional regulation by RUNX2
|
|
R-HSA-8878159
|
Transcriptional regulation by RUNX3
|
|
R-HSA-8864260
|
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
|
|
R-HSA-5656121
|
Translesion synthesis by POLI
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R-HSA-5655862
|
Translesion synthesis by POLK
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