Reactome | aptf-1 [nucleoplasm]

aptf-1 [nucleoplasm]

Stable Identifier

R-CEL-3234071

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

monoSUMO1-K10-TFAP2C, Q09585

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Caenorhabditis elegans)
      - Negative regulation of activity of TFAP2 (AP-2) family transcription factors (Caenorhabditis elegans)
        
        SUMOylation of TFAP2C with SUMO1 (Caenorhabditis elegans)
        
        SUMO1:TFAP2C homodimer [nucleoplasm] (Caenorhabditis elegans)
        
        aptf-1 [nucleoplasm] (Caenorhabditis elegans)

Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - SUMOylation (Caenorhabditis elegans)
    - SUMO E3 ligases SUMOylate target proteins (Caenorhabditis elegans)
      - SUMOylation of transcription factors (Caenorhabditis elegans)
        
        SUMOylation of TFAP2C with SUMO1 (Caenorhabditis elegans)
        
        SUMO1:TFAP2C homodimer [nucleoplasm] (Caenorhabditis elegans)
        
        aptf-1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q09585

Gene Names

aptf-1

Reference Genes

BioGPS Gene:187043 aptf-1

ENSEMBL:WBGene00019424

KEGG:cel:CELE_K06A1.1 aptf-1

Monarch:187043 aptf-1

NCBI Gene:187043 aptf-1

UCSC:Q09585 aptf-1

Wormbase:WBGene00019424

Wormbase:WBGene00019424 aptf-1

Reference Transcript

RefSeq:NM_062899.4 aptf-1

Other Identifiers

187043

GO:0000977

GO:0001228

GO:0003677

GO:0003700

GO:0005634

GO:0006355

GO:0030431

GO:0042127

GO:0045944

Participates

as a component of

SUMO1:TFAP2C homodimer [nucleoplasm] (Caenorhabditis elegans)

Other forms of this molecule

aptf-1 [cytosol]

aptf-1 [nucleoplasm]

Inferred From

monoSUMO1-K10-TFAP2C [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 10 (in Homo sapiens)

Coordinate

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_495300.2

ENSEMBL

K06A1.1.1, K06A1.1.1, WBGene00019424

PRO

Q09585

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