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FRS2 [cytosol]
Stable Identifier
R-CFA-190244
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
FRS2, A0A8I3P4L9
Locations in the PathwayBrowser
Expand all
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
Signalling to ERKs (Canis familiaris)
Prolonged ERK activation events (Canis familiaris)
Frs2-mediated activation (Canis familiaris)
FRS2 binds to active TrkA receptor (Canis familiaris)
Active TrkA receptor:FRS2 complex [endosome membrane] (Canis familiaris)
FRS2 [cytosol] (Canis familiaris)
FRS2 [cytosol] (Canis familiaris)
FRS2 is phosphorylated by active TrkA receptor (Canis familiaris)
Active TrkA receptor:FRS2 complex [endosome membrane] (Canis familiaris)
FRS2 [cytosol] (Canis familiaris)
Signaling by NTRK2 (TRKB) (Canis familiaris)
Activated NTRK2 signals through FRS2 and FRS3 (Canis familiaris)
Activated NTRK2 binds FRS2 (Canis familiaris)
BDNF,NTF4:p-5Y-NTRK2:FRS2 [plasma membrane] (Canis familiaris)
FRS2 [cytosol] (Canis familiaris)
FRS2 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3P4L9
Gene Names
FRS2
Reference Genes
BioGPS Gene:474444 FRS2
ENSEMBL:ENSCAFG00845017484.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845017484.1 FRS2
KEGG Gene (Canis lupus familiaris):474444 FRS2
Monarch:474444 FRS2
NCBI Gene:474444 FRS2
Reference Transcript
RefSeq:XM_005625613.2 FRS2
RefSeq:XM_005625611.1 FRS2
RefSeq:XM_005625610.2 FRS2
RefSeq:XM_005625612.2 FRS2
Other Identifiers
474444
Cfa.19573.1.S1_at
Cfa.1958.1.S1_at
Cfa.1958.2.A1_at
CfaAffx.1604.1.S1_s_at
GO:0001702
GO:0001759
GO:0002088
GO:0003281
GO:0005068
GO:0005104
GO:0005168
GO:0005737
GO:0005886
GO:0005911
GO:0005912
GO:0007169
GO:0007405
GO:0008543
GO:0008595
GO:0012501
GO:0022414
GO:0023052
GO:0030154
GO:0030900
GO:0042981
GO:0043410
GO:0046619
GO:0048856
GO:0050678
GO:0060090
GO:0060527
GO:0070307
GO:0070372
GO:2000726
Participates
as an input of
Activated NTRK2 binds FRS2 (Canis familiaris)
FRS2 binds to active TrkA receptor (Canis familiaris)
as a component of
BDNF,NTF4:p-5Y-NTRK2:FRS2 [plasma membrane] (Canis familiaris)
Active TrkA receptor:FRS2 complex [endosome membrane] (Canis familiaris)
Other forms of this molecule
phospho-FRS2 [cytosol]
phospho-FRS2 [cytosol]
phospho-FRS2 [plasma membrane]
FRS2 [plasma membrane]
phospho-FRS2 [plasma membrane]
Inferred From
FRS2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_005625668.1
,
XP_005625669.1
,
XP_005625667.1
,
XP_005625670.1
OpenTargets
ENSG00000166225
Ensembl
ENSCAFG00845017484
,
ENSCAFT00845030983
,
ENSCAFP00845024277
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