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HSPA8 [cytosol]
Stable Identifier
R-CFA-264476
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
E2R0T6
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to heat stress (Canis familiaris)
Regulation of HSF1-mediated heat shock response (Canis familiaris)
HSP110s exchange ATP for ADP on HSP70s:ADP (Canis familiaris)
HSP70s:ADP [cytosol] (Canis familiaris)
HSPA8:ADP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP70s:ATP [cytosol] (Canis familiaris)
HSPA8:ATP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Canis familiaris)
HSP70s:ADP [cytosol] (Canis familiaris)
HSPA8:ADP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP70s:ATP [cytosol] (Canis familiaris)
HSPA8:ATP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
Hikeshi binds HSP70s:ATP (Canis familiaris)
HSP70s:ATP [cytosol] (Canis familiaris)
HSPA8:ATP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
Hikeshi:HSP70s:ATP [cytosol] (Canis familiaris)
HSP70s:ATP [cytosol] (Canis familiaris)
HSPA8:ATP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Canis familiaris)
Hikeshi:HSP70s:ATP [cytosol] (Canis familiaris)
HSP70s:ATP [cytosol] (Canis familiaris)
HSPA8:ATP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Canis familiaris)
ATP binding to HSP90 triggers conformation change (Canis familiaris)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP90:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
ATP hydrolysis by HSP70 (Canis familiaris)
HSP40:HSP70:ADP:nascent protein [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP40:HSP70:ATP:nascent protein [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Canis familiaris)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Canis familiaris)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP70 binds to HSP40:nascent protein (Canis familiaris)
HSP40:HSP70:ATP:nascent protein [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP70:ATP [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Canis familiaris)
HSP40:HSP70:ADP:nascent protein [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSP90:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
HSP70 proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
Metabolism of RNA (Canis familiaris)
Regulation of mRNA stability by proteins that bind AU-rich elements (Canis familiaris)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Canis familiaris)
AUF1 (hnRNP D0) is ubiquitinylated (Canis familiaris)
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
AUF1 binds translation and heat shock proteins (Canis familiaris)
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
Clathrin-mediated endocytosis (Canis familiaris)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Canis familiaris)
HSPA8:ATP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
HSPA8:ATP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
HSPA8:ATP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
clathrin:HSPA8:ADP [cytosol] (Canis familiaris)
HSPA8:ADP [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
trans-Golgi Network Vesicle Budding (Canis familiaris)
Golgi Associated Vesicle Biogenesis (Canis familiaris)
trans-Golgi Network Derived Vesicle Uncoating (Canis familiaris)
HSC70:Auxillin Complex [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
Lysosome Vesicle Biogenesis (Canis familiaris)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Canis familiaris)
HSC70:Auxillin Complex [cytosol] (Canis familiaris)
HSPA8 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:E2R0T6
Reference Genes
ENSEMBL:ENSCAFG00000011666
Other Identifiers
479406
607182
Cfa.273.6.S1_s_at
Participates
as a component of
HSC70:Auxillin Complex [cytosol] (Canis familiaris)
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Canis familiaris)
HSPA8:ADP [cytosol] (Canis familiaris)
HSPA8:ATP [cytosol] (Canis familiaris)
as an input of
AUF1 binds translation and heat shock proteins (Canis familiaris)
as a member of
HSP70 proteins [cytosol] (Canis familiaris)
Other forms of this molecule
Me3K561-HSPA8 [nucleoplasm]
HSPA8 [secretory granule lumen]
HSPA8 [extracellular region]
HSPA8 [ficolin-1-rich granule lumen]
HSPA8 [nucleoplasm]
HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
Inferred From
HSPA8 [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSCAFP00845018012
,
ENSCAFG00845012887
,
ENSCAFT00845022977
VGNC
59028
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