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Axn [cytosol]
Stable Identifier
R-DME-4641133
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
ub-AXIN1, Q9V407
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
TCF dependent signaling in response to WNT (Drosophila melanogaster)
Degradation of AXIN (Drosophila melanogaster)
AXIN is ubiquitinated by SMURF2 (Drosophila melanogaster)
ub-AXIN:SMURF2 [cytosol] (Drosophila melanogaster)
Axn [cytosol] (Drosophila melanogaster)
Ubiquitinated AXIN is degraded by the proteasome (Drosophila melanogaster)
ub-AXIN:SMURF2 [cytosol] (Drosophila melanogaster)
Axn [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9V407 Axn
Gene Names
Axn, CG7926
Chain
chain:1-745
Reference Genes
BioGPS Gene:43565 Axn
CTD Gene:43565 Axn
KEGG Gene (Drosophila melanogaster):Dmel_CG7926 Axn
Monarch:43565 Axn
NCBI Gene:43565 Axn
UCSC:Q9V407 Axn
Reference Transcript
RefSeq:NM_170457.3 Axn
RefSeq:NM_170458.2 Axn
Other Identifiers
154838_at
1632134_s_at
43565
GO:0005102
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0005975
GO:0005977
GO:0006091
GO:0007367
GO:0007450
GO:0007455
GO:0007507
GO:0008013
GO:0008587
GO:0010941
GO:0012501
GO:0016055
GO:0019901
GO:0022414
GO:0023052
GO:0030154
GO:0030163
GO:0030707
GO:0030877
GO:0031625
GO:0032436
GO:0035019
GO:0035293
GO:0036211
GO:0042594
GO:0043226
GO:0045860
GO:0048468
GO:0048477
GO:0048856
GO:0060090
GO:0090090
GO:1900117
GO:1990909
Participates
as a component of
ub-AXIN:SMURF2 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
AXN [cytosol]
Phospho AXN [cytosol]
Phospho (3 sites) AXN [cytosol]
Axn [cytosol]
Axn [cytosol]
phospho-Axn [cytosol]
Axn [cytosol]
Inferred From
ub-AXIN [cytosol]
(Homo sapiens)
ub-AXIN1 [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at 505 (in Homo sapiens)
Coordinate
505
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_733336.1
,
NP_733337.1
Flybase
FBgn0026597
PRO
Q9V407
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P18824 arm
20
arm [nucleoplasm]
(R-DME-3451168)
arm [cytosol]
(R-DME-448839)
arm [cytosol]
(R-DME-202930)
arm [cytosol]
(R-DME-202950)
phospho-arm [cytosol]
(R-DME-8942374)
phospho-arm [cytosol]
(R-DME-8942369)
phospho-arm [cytosol]
(R-DME-8942367)
phospho-arm [cytosol]
(R-DME-8942363)
arm [plasma membrane]
(R-DME-9038440)
arm [plasma membrane]
(R-DME-437260)
arm [ficolin-1-rich granule lumen]
(R-DME-6801028)
arm [extracellular region]
(R-DME-6806309)
arm [specific granule lumen]
(R-DME-6799534)
phospho-arm [cytosol]
(R-DME-3134933)
phospho-arm [nucleoplasm]
(R-DME-3134926)
arm [cytosol]
(R-DME-201598)
Phospho (4 sites) ARM [cytosol]
(R-DME-205960)
ARM [cytosol]
(R-DME-205774)
Phospho ARM [cytosol]
(R-DME-206159)
ARM [nucleoplasm]
(R-DME-205878)
0.508
2
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