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AXN [cytosol]
Stable Identifier
R-DME-206017
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Circadian Clock pathway (Drosophila melanogaster)
Phosphorylation of PER and TIM (Drosophila melanogaster)
PER is phosphorylated by DCO (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
AXN [cytosol] (Drosophila melanogaster)
Wingless pathway (Drosophila melanogaster)
WG ligand bound to FZ receptors (Drosophila melanogaster)
Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM (Drosophila melanogaster)
Destabilisation and degradation of AXN in the 'destruction complex' (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:AXN:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
AXN [cytosol] (Drosophila melanogaster)
Inhibition of SGG results in the dephosphorylation of the 'destruction complex' by PP2A and release of ARM (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:AXN:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
AXN [cytosol] (Drosophila melanogaster)
WG ligand not bound to FZ receptors (Drosophila melanogaster)
Assembly of the 'destruction complex' (Drosophila melanogaster)
Formation of the 'destruction complex' (Drosophila melanogaster)
AXN [cytosol] (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
AXN [cytosol] (Drosophila melanogaster)
Phosphorylation of AXN and APC (Drosophila melanogaster)
Phosphorylation of AXN and APC by DCO (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
AXN [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9V407 Axn
Gene Names
Axn, CG7926
Chain
chain:1-745
Reference Genes
BioGPS Gene:43565 Axn
CTD Gene:43565 Axn
KEGG:dme:Dmel_CG7926 Axn
Monarch:43565 Axn
NCBI Gene:43565 Axn
UCSC:Q9V407 Axn
Reference Transcript
RefSeq:NM_170457.3 Axn
RefSeq:NM_170458.2 Axn
Other Identifiers
154838_at
1632134_s_at
43565
GO:0005102
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0005975
GO:0005977
GO:0006091
GO:0007367
GO:0007450
GO:0007455
GO:0007507
GO:0008013
GO:0008587
GO:0010941
GO:0016055
GO:0019901
GO:0022414
GO:0030707
GO:0030877
GO:0031625
GO:0032436
GO:0035019
GO:0035293
GO:0042594
GO:0043226
GO:0045860
GO:0048468
GO:0048477
GO:0048856
GO:0060090
GO:0090090
GO:1900117
GO:1990909
Participates
as an input of
Formation of the 'destruction complex' (Drosophila melanogaster)
as a component of
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Phospho AXN [cytosol]
Phospho (3 sites) AXN [cytosol]
Axn [cytosol]
Axn [cytosol]
Axn [cytosol]
phospho-Axn [cytosol]
Axn [cytosol]
Cross References
RefSeq
NP_733337.1
,
NP_733336.1
ENSEMBL
FBpp0084921
,
FBtr0085555
,
FBtr0085553
,
FBpp0084919
FlyBase
FBgn0026597
PRO
Q9V407
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P18824 arm
20
arm [nucleoplasm]
(R-DME-3451168)
arm [cytosol]
(R-DME-448839)
arm [cytosol]
(R-DME-202930)
arm [cytosol]
(R-DME-202950)
arm [plasma membrane]
(R-DME-9038440)
arm [plasma membrane]
(R-DME-437260)
phospho-arm [cytosol]
(R-DME-8942374)
phospho-arm [cytosol]
(R-DME-8942369)
phospho-arm [cytosol]
(R-DME-8942367)
phospho-arm [cytosol]
(R-DME-8942363)
phospho-arm [cytosol]
(R-DME-3134933)
phospho-arm [nucleoplasm]
(R-DME-3134926)
arm [specific granule lumen]
(R-DME-6799534)
arm [extracellular region]
(R-DME-6806309)
arm [ficolin-1-rich granule lumen]
(R-DME-6801028)
arm [cytosol]
(R-DME-201598)
Phospho (4 sites) ARM [cytosol]
(R-DME-205960)
ARM [cytosol]
(R-DME-205774)
Phospho ARM [cytosol]
(R-DME-206159)
ARM [nucleoplasm]
(R-DME-205878)
0.508
2
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