Reactome | Sfmbt [nucleoplasm]

Sfmbt [nucleoplasm]

Stable Identifier

R-DME-6804477

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

L3MBTL2, Q9VK33

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - Generic Transcription Pathway (Drosophila melanogaster)
    - Transcriptional Regulation by E2F6 (Drosophila melanogaster)
      - CBX3 and PRC1.6 associate with E2F6.com-1 (Drosophila melanogaster)
        
        E2F6:TFDP1:MGA:MAX:EHMT1:EHMT2:CBX3:PRC1.6 [nucleoplasm] (Drosophila melanogaster)
        
        PRC1.6 (PCGF6:L3MBTL2:RING1,RNF2:YAF2) [nucleoplasm] (Drosophila melanogaster)
        
        Sfmbt [nucleoplasm] (Drosophila melanogaster)
        
        PRC1.6 (PCGF6:L3MBTL2:RING1,RNF2:YAF2) [nucleoplasm] (Drosophila melanogaster)
        
        Sfmbt [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VK33

Gene Names

Sfmbt

Reference Genes

BioGPS Gene:34709 Sfmbt

CTD Gene:34709 Sfmbt

ENSEMBL:FBgn0032475

FlyBase:FBgn0032475

KEGG:dme:Dmel_CG16975 Sfmbt

Monarch:34709 Sfmbt

NCBI Gene:34709 Sfmbt

UCSC:Q9VK33 Sfmbt

Reference Transcript

Other Identifiers

153821_at

1636691_a_at

34709

GO:0003677

GO:0003682

GO:0005515

GO:0005634

GO:0006325

GO:0006355

GO:0007446

GO:0008270

GO:0010629

GO:0022414

GO:0031507

GO:0031519

GO:0032991

GO:0035064

GO:0042393

GO:0045892

GO:0046872

GO:0048477

GO:0048856

Participates

as an input of

PIAS1 SUMOylates L3MBTL2 with SUMO2 (Drosophila melanogaster)

as a component of

Other forms of this molecule

Sfmbt [nucleoplasm]

Inferred From

L3MBTL2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_723786.1, NP_609606.2, NP_001260432.1

ENSEMBL

FBgn0032475, FBpp0305438, FBtr0080492, FBpp0080070, FBtr0333236

FlyBase

FBgn0032475

PRO

Q9VK33

PDB

3H6Z, 4C5E, 5J8Y, 4C5G, 4C5H

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8ST83	1	pho [nucleoplasm] (R-DME-4086091)	0.702	8
UniProt:P62805 H4C1	17	HIST1H4 [nucleoplasm] (R-HSA-181902) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) HIST1H4A [extracellular region] (R-HSA-977569) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) monoSUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) polySUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531)	0.558	10
UniProt:Q9VSZ3 Q9VSZ3			0.499	2