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VAV2 [cytosol]
Stable Identifier
R-GGA-195012
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
VAV2, A0A8V1AAH7
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
EPH-Ephrin signaling (Gallus gallus)
EPH-ephrin mediated repulsion of cells (Gallus gallus)
SFKs phosphorylate VAV2,3 (Gallus gallus)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Gallus gallus)
VAV2,VAV3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
p-EPHs bind VAV2,3 (Gallus gallus)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Gallus gallus)
VAV2,VAV3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
VAV2,VAV3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Hemostasis (Gallus gallus)
Platelet activation, signaling and aggregation (Gallus gallus)
GPVI-mediated activation cascade (Gallus gallus)
VAV1 is a GEF for Rho/Rac family GTPases (Gallus gallus)
PIP3:VAV1,2,3 [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
VAV family:PIP2 [plasma membrane] (Gallus gallus)
VAV family [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
p-SLP-76 binds VAV (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
p-SLP-76:VAV [cytosol] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
DAP12 interactions (Gallus gallus)
DAP12 signaling (Gallus gallus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] (Gallus gallus)
VAV2,VAV3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Gallus gallus)
VAV2,VAV3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Recruitment of VAV and BTK to p-SLP-76 (Gallus gallus)
VAV2,VAV3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] (Gallus gallus)
VAV2,VAV3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Release of p-PLCG1 (Gallus gallus)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV [plasma membrane] (Gallus gallus)
VAV2,VAV3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Gallus gallus)
VAV2,VAV3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated Ca+2 mobilization (Gallus gallus)
Autophosphorylation of BTK/ITK (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-TEC kinases [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Hydrolysis of PIP2 by PLCG (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3 [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Phosphorylation of TEC kinases by p-SYK (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:TEC kinases:PIP3 [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
FCERI mediated MAPK activation (Gallus gallus)
Phosphorylation and activation of VAV (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Recruitment of VAV to p-SLP-76 (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
Regulation of actin dynamics for phagocytic cup formation (Gallus gallus)
Phosphorylation of VAV (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Recruitment of VAV1 to p-6Y-SYK (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
p75 NTR receptor-mediated signalling (Gallus gallus)
Cell death signalling via NRAGE, NRIF and NADE (Gallus gallus)
NRAGE signals death through JNK (Gallus gallus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Gallus gallus)
GEFs [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (12/13) signalling events (Gallus gallus)
GEFs activate RhoA,B,C (Gallus gallus)
GEFs [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
Src kinases phosphorylate VAV (Gallus gallus)
PIP3:VAV1,2,3 [plasma membrane] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
VAV family [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
CDC42 GTPase cycle (Gallus gallus)
CDC42 GEFs activate CDC42 (Gallus gallus)
CDC42 GEFs [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
RAC1 GTPase cycle (Gallus gallus)
RAC1 GEFs activate RAC1 (Gallus gallus)
RAC1 GEFs [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
RAC2 GTPase cycle (Gallus gallus)
RAC2 GEFs activate RAC2 (Gallus gallus)
RAC2 GEFs [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
RAC3 GTPase cycle (Gallus gallus)
RAC3 GEFs activate RAC3 (Gallus gallus)
RAC3 GEFs [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
RHOA GTPase cycle (Gallus gallus)
RHOA GEFs activate RHOA (Gallus gallus)
RHOA GEFs [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
RHOB GTPase cycle (Gallus gallus)
RHOB GEFs activate RHOB (Gallus gallus)
RHOB GEFs [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
RHOC GTPase cycle (Gallus gallus)
RHOC GEFs activate RHOC (Gallus gallus)
RHOC GEFs [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
RHOG GTPase cycle (Gallus gallus)
RHOG GEFs activate RHOG (Gallus gallus)
RHOG GEFs [cytosol] (Gallus gallus)
VAV2 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V1AAH7
Gene Names
VAV2
Reference Genes
ENSEMBL:ENSGALG00010028884.1
UCSC:A0A8V1AAH7 VAV2
Other Identifiers
373938
GO:0001784
GO:0002768
GO:0005085
GO:0005154
GO:0005515
GO:0005737
GO:0005886
GO:0007165
GO:0007264
GO:0008270
GO:0016020
GO:0016477
GO:0030031
GO:0030032
GO:0035556
GO:0046872
GO:0048870
GO:0051897
GT_A_87_P015170
GT_A_87_P035296
GT_A_87_P262098
GT_A_87_P307413
Gga.17419.1.S1_at
Gga.4341.1.S1_at
Gga.4341.2.S1_a_at
Participates
as a member of
RHOA GEFs [cytosol] (Gallus gallus)
RHOC GEFs [cytosol] (Gallus gallus)
RAC2 GEFs [cytosol] (Gallus gallus)
RAC1 GEFs [cytosol] (Gallus gallus)
RHOB GEFs [cytosol] (Gallus gallus)
RAC3 GEFs [cytosol] (Gallus gallus)
VAV2,VAV3 [cytosol] (Gallus gallus)
GEFs [cytosol] (Gallus gallus)
VAV family [cytosol] (Gallus gallus)
VAV1,2,3 [cytosol] (Gallus gallus)
as a candidate of
CDC42 GEFs [cytosol] (Gallus gallus)
RHOG GEFs [cytosol] (Gallus gallus)
Other forms of this molecule
phospho-VAV2 [cytosol]
Inferred From
VAV2 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSGALT00010069858
,
ENSGALP00010042984
,
ENSGALG00010028884
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