POLH [nucleoplasm]

Stable Identifier
R-HSA-110287
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Pol eta protein, DNA polymerase eta
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q9Y253 POLH
Gene Names
POLH, RAD30, RAD30A, XPV
Chain
chain:1-713
Reference Genes
BioGPS Gene:5429 POLH
COSMIC (genes):POLH POLH
CTD Gene:5429 POLH
dbSNP Gene:5429 POLH
ENSEMBL:ENSG00000170734 POLH
HGNC:9181 POLH
KEGG:hsa:5429 POLH
Monarch:5429 POLH
NCBI Gene:5429 POLH
OMIM:603968 POLH
UCSC:Q9Y253 POLH
Reference Transcript
Other Identifiers
11729178_at
11729179_x_at
11752223_x_at
11754902_a_at
1557700_PM_at
1557700_at
1557701_PM_s_at
1557701_s_at
17009054
219380_3p_x_at
219380_PM_x_at
219380_x_at
222879_PM_s_at
222879_s_at
231115_PM_at
231115_at
233852_PM_at
233852_at
2908101
2908103
2908104
2908105
2908108
2908109
2908110
2908111
2908112
2908118
2908119
2908120
2908121
2908122
2908123
2908124
2908125
2908126
2908127
2908128
2908129
2908130
2908131
2908132
2908133
2908134
2908135
2908136
2908138
2908139
2908141
2908143
3828219
5429
8119858
81712_at
A_14_P113059
A_14_P118268
A_32_P69492
A_32_P96692
GE79909
GO:0000731
GO:0003677
GO:0003684
GO:0003824
GO:0003887
GO:0005515
GO:0005634
GO:0005654
GO:0005657
GO:0005829
GO:0006260
GO:0006281
GO:0006282
GO:0006290
GO:0006301
GO:0009314
GO:0010225
GO:0016740
GO:0034654
GO:0035861
GO:0042276
GO:0043226
GO:0046872
GO:0070987
GO:0071494
GO:0071897
GO:0140097
HMNXSV003025742
HMNXSV003026209
Hs.123140.0.A1_3p_at
Hs.155573.1.S1_3p_at
Hs2.407274.1.A1_3p_s_at
ILMN_1658221
ILMN_2136576
PH_hs_0009372
TC06000605.hg
g5457143_3p_a_at
Participates
as a member of
as an input of
as a component of
as an output of
as a candidate of
Other forms of this molecule
MonoUb-K682,K686,K694,K709-POLH [nucleoplasm]
Inferred To
polh [nucleoplasm] (Danio rerio)
polh [nucleoplasm] (Xenopus tropicalis)
POLH [nucleoplasm] (Bos taurus)
POLH [nucleoplasm] (Canis familiaris)
POLH [nucleoplasm] (Drosophila melanogaster)
POLH [nucleoplasm] (Gallus gallus)
POLH [nucleoplasm] (Mus musculus)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Sus scrofa)
polh-1 [nucleoplasm] (Caenorhabditis elegans)
Ghost homologue of POLH [nucleoplasm] (Plasmodium falciparum)
Polh [nucleoplasm] (Rattus norvegicus)
Cross References
RefSeq
OpenTargets
ENSEMBL
HPA
ZINC - Substances
ZINC target
PRO
Pharos - Targets
Orphanet
GlyGen
HMDB Protein
PDB
7U7S, 8E8G, 4ECU, 8E86, 6M7T, 5KFU, 8GBF, 7M7M, 6WK6, 6PL7, 6V5K, 3MR3, 5KFJ, 5KFB, 8GML, 8UJT, 5KFQ, 7M86, 4Q8F, 6UI2, 7U78, 7M7R, 7U7W, 4YP3, 8V7C, 4J9L, 7M84, 7M8D, 8GKR, 4O3P, 4ECY, 4RNN, 6W5X, 6MP3, 8E85, 5L1J, 3MR2, 4ECT, 6MXO, 7LCD, 7M81, 5KG3, 4DL7, 5KFC, 5L9X, 5DG8, 7M7U, 8FN3, 2I5O, 7U7A, 7U77, 8V7F, 5DG7, 4ED2, 8V7J, 7U7I, 7U83, 7M7S, 4J9K, 3TQ1, 5DQH, 4ECX, 8E8J, 5KG7, 5KFF, 4ECS, 6M7U, 5L1K, 4ECZ, 6M7O, 5KFR, 7M7P, 2LSK, 5KFK, 5KFA, 5DG9, 7U81, 4YR3, 4Q8E, 4J9R, 4O3O, 8V7E, 8EVF, 8V7I, 7M82, 4ECQ, 7U72, 7U7R, 5DQI, 8SKI, 4RNM, 4ED8, 6D0M, 3JAA, 5KFV, 5L1I, 4DL3, 5KFN, 5DGB, 5KG4, 4ED3, 5JUM, 7U7G, 6M7P, 8UK4, 4DL6, 8G8J, 7M89, 4YR2, 7U7D, 8FOG, 8V7H, 7U7V, 4J9Q, 4O3N, 8V7K, 4ED1, 7M7Q, 4O3S, 7M7Z, 7M7Y, 4EEY, 6PZ3, 8E8B, 5KFW, 4ECW, 8E8D, 3WUP, 5KG0, 5KFG, 5KFS, 5DGA, 4ECR, 7M80, 5KFZ, 7U79, 8UJX, 5KFH, 7U80, 7M7L, 4YR0, 8V7G, 4J9P, 8EVE, 7U7Z, 4O3R, 7U7L, 4ED0, 4J9S, 7U82, 7L69, 5F9N, 5DQG, 8E8A, 4ED7, 8E88, 3MR6, 5KG5, 8E8C, 6PLC, 5KFO, 7U7F, 4DL2, 5KFX, 5KG1, 7M7O, 8UJV, 4DL5, 7M88, 7U76, 7U7C, 5EWG, 7U74, 7M85, 7U7U, 8V7B, 4J9O, 7M8C, 5F9L, 8E8H, 6UQI, 4ECV, 8E87, 3MR5, 8E8F, 5KFT, 5KFD, 5KFL, 7M7N, 5KFY, 3SI8, 5KFP, 5KFI, 7U7B, 7U75, 7U7J, 5DLF, 7U7X, 4J9N, 7M7T, 8V7A, 7U7Y, 4O3Q, 5EWE, 7U84, 6D0Z, 4RU9, 4RNO, 8E89, 6M7V, 5L1L, 8E8E, 4ED6, 5KG6, 6Q02, 6PL8, 5KFM, 5KFE, 7U7E, 7M87, 5KG2, 4YQW, 5DLG, 4DL4, 8G8H, 8E8K, 6MQ8, 7M83, 7M8A, 8V7D, 7M8B, 7U7K, 4J9M, 7U73, 5EWF, 7U7T
Interactors (5)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P51587 BRCA2  20 0.676 6
 UniProt:Q86YC2 PALB2  20 0.672 7
 UniProt:P0CG48 UBC  20 0.658 4
 UniProt:Q6FI35 Q6FI35      0.527 3
 UniProt:P10275 AR  4 0.471 2
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