Reactome | MYO1C [cytosol]

MYO1C [cytosol]

Stable Identifier

R-HSA-1449619

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Myosin-Ic, MYO1C_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O00159 MYO1C

Gene Names

MYO1C

Chain

chain:1-1063

Reference Genes

BioGPS Gene:4641 MYO1C

COSMIC - genes:MYO1C MYO1C

CTD Gene:4641 MYO1C

dbSNP Gene:4641 MYO1C

ENSEMBL:ENSG00000197879 MYO1C

HGNC:7597 MYO1C

KEGG:hsa:4641 MYO1C

Monarch:4641 MYO1C

NCBI Gene:4641 MYO1C

OMIM:606538 MYO1C

UCSC:O00159 MYO1C

Reference Transcript

Participates

as a component of

as a member of

Myosin [cytosol] (Homo sapiens)

Inferred To

MYO1C [cytosol] (Bos taurus)

MYO1C [cytosol] (Canis familiaris)

MYO1C [cytosol] (Danio rerio)

MYO1C [cytosol] (Dictyostelium discoideum)

MYO1C [cytosol] (Drosophila melanogaster)

MYO1C [cytosol] (Gallus gallus)

MYO1C [cytosol] (Rattus norvegicus)

MYO1C [cytosol] (Sus scrofa)

MYO1C [cytosol] (Xenopus tropicalis)

Myo1c [cytosol] (Mus musculus)

Cross References

RefSeq

NP_001074248.1, XP_047292089.1, NP_001074419.1, XP_054172221.1, NP_203693.3, XP_054172217.1, XP_054172220.1, XP_047292092.1, XP_024306537.1, XP_024306536.1, XP_047292093.1, XP_047292090.1, XP_054172218.1, XP_054172219.1

OpenTargets

ENSG00000197879

ENSEMBL

ENSP00000354283, ENST00000570984, ENSP00000493973, ENSP00000496799, ENSP00000496954, ENST00000648651, ENST00000361007, ENSG00000197879, ENST00000648446, ENSP00000459174, ENSP00000459271, ENST00000646049, ENST00000575158

HPA

ENSG00000197879-MYO1C

GeneCards

MYO1C

PRO

O00159

Pharos - Targets

O00159

Orphanet

MYO1C

GlyGen

O00159

PDB

4BYF

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.615	20
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:P01100 FOS	2	FOS [nucleoplasm] (R-HSA-450216) p-T325,T331,S362,S374-FOS [nucleoplasm] (R-HSA-450283)	0.483	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-ESR1 [cytosol] (R-HSA-9632177) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.462	2

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