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CDKN2D [cytosol]
Stable Identifier
R-HSA-182580
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Cyclin-dependent kinase 4 inhibitor D, p19-INK4d
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1 Phase (Homo sapiens)
Cyclin D associated events in G1 (Homo sapiens)
Association of INK4 family proteins with CDK4/6 (Homo sapiens)
CDK4,CDK6:INK4 [cytosol] (Homo sapiens)
INK4 [cytosol] (Homo sapiens)
CDKN2D [cytosol] (Homo sapiens)
INK4 [cytosol] (Homo sapiens)
CDKN2D [cytosol] (Homo sapiens)
Formation of CDK4/6:CCND complexes (Homo sapiens)
CDK4,CDK6:INK4 [cytosol] (Homo sapiens)
INK4 [cytosol] (Homo sapiens)
CDKN2D [cytosol] (Homo sapiens)
INK4 [cytosol] (Homo sapiens)
CDKN2D [cytosol] (Homo sapiens)
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Oncogene Induced Senescence (Homo sapiens)
Association of INK4 family proteins with CDK4/6 (Homo sapiens)
CDK4,CDK6:INK4 [cytosol] (Homo sapiens)
INK4 [cytosol] (Homo sapiens)
CDKN2D [cytosol] (Homo sapiens)
INK4 [cytosol] (Homo sapiens)
CDKN2D [cytosol] (Homo sapiens)
Oxidative Stress Induced Senescence (Homo sapiens)
Association of INK4 family proteins with CDK4/6 (Homo sapiens)
CDK4,CDK6:INK4 [cytosol] (Homo sapiens)
INK4 [cytosol] (Homo sapiens)
CDKN2D [cytosol] (Homo sapiens)
INK4 [cytosol] (Homo sapiens)
CDKN2D [cytosol] (Homo sapiens)
Senescence-Associated Secretory Phenotype (SASP) (Homo sapiens)
Association of INK4 family proteins with CDK4/6 (Homo sapiens)
CDK4,CDK6:INK4 [cytosol] (Homo sapiens)
INK4 [cytosol] (Homo sapiens)
CDKN2D [cytosol] (Homo sapiens)
INK4 [cytosol] (Homo sapiens)
CDKN2D [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P55273 CDKN2D
Gene Names
CDKN2D
Chain
chain:1-166
Reference Genes
BioGPS Gene:1032 CDKN2D
COSMIC (genes):CDKN2D CDKN2D
CTD Gene:1032 CDKN2D
dbSNP Gene:1032 CDKN2D
ENSEMBL:ENSG00000129355 CDKN2D
ENSEMBL_homo_sapiens_GENE:ENSG00000129355.7 CDKN2D
HGNC:1790 CDKN2D
KEGG Gene (Homo sapiens):1032 CDKN2D
Monarch:1032 CDKN2D
NCBI Gene:1032 CDKN2D
OMIM:600927 CDKN2D
UCSC:P55273 CDKN2D
Reference Transcript
RefSeq:NM_079421.2 CDKN2D
RefSeq:NM_001800.3 CDKN2D
Other Identifiers
1032
11725107_at
16868793
1797_at
210240_PM_s_at
210240_s_at
3850444
3850446
3850447
3850449
3850450
3850451
8034075
ADDON002772.hg
ADDON002773.hg
A_23_P89941
GE59136
GO:0000079
GO:0000278
GO:0000731
GO:0004861
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006281
GO:0007049
GO:0007605
GO:0008285
GO:0009411
GO:0012501
GO:0019901
GO:0023052
GO:0030308
GO:0032526
GO:0033280
GO:0036211
GO:0042326
GO:0043154
GO:0043226
GO:0048102
GO:0050877
GO:0097129
GO:0098772
GO:1902230
GO:1902807
GO:2000045
HMNXSV003015460
ILMN_1740597
ILMN_1748883
PH_hs_0025379
TC19001170.hg
U40343_at
g1161921_3p_at
Participates
as a member of
INK4 [cytosol] (Homo sapiens)
Inferred To
CDKN2D [cytosol]
(Bos taurus)
CDKN2D [cytosol]
(Canis familiaris)
Cdkn2d [cytosol]
(Rattus norvegicus)
cdkn2d [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_524145.1
,
NP_001791.1
OpenTargets
ENSG00000129355
HPA
ENSG00000129355-CDKN2D
GeneCards
P55273
Ensembl
ENSG00000129355
,
ENSP00000377224
,
ENST00000393599
,
ENSP00000337056
,
ENST00000335766
PRO
P55273
Pharos - Targets
P55273
PDB
1BI8
,
1BD8
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P11802 CDK4
3
CDK4 [cytosol]
(R-HSA-68330)
CDK4 [nucleoplasm]
(R-HSA-113843)
p-T172-CDK4 [nucleoplasm]
(R-HSA-113830)
0.966
28
UniProt:Q00534 CDK6
3
CDK6 [cytosol]
(R-HSA-68336)
CDK6 [nucleoplasm]
(R-HSA-141283)
p-T177-CDK6 [nucleoplasm]
(R-HSA-69628)
0.957
26
UniProt:P22736 NR4A1
2
p-S351-NR4A1 [nucleoplasm]
(R-HSA-199846)
NR4A1 [nucleoplasm]
(R-HSA-199831)
0.666
4
UniProt:P43354 NR4A2
2
NR4A2 [nucleoplasm]
(R-HSA-376305)
polySUMO2,3-K558,K577-NR4A2 [nucleoplasm]
(R-HSA-4755517)
0.666
4
UniProt:P25786 PSMA1
2
PSMA1 [nucleoplasm]
(R-HSA-174333)
PSMA1 [cytosol]
(R-HSA-68724)
0.556
3
UniProt:P30281 CCND3
2
CCND3 [cytosol]
(R-HSA-68333)
CCND3 [nucleoplasm]
(R-HSA-113835)
0.556
3
UniProt:O00560 SDCBP
3
SDCBP [extracellular region]
(R-HSA-6806206)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [cytosol]
(R-HSA-373639)
0.556
3
UniProt:Q92570 NR4A3
1
NR4A3 [nucleoplasm]
(R-HSA-8938004)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
UniProt:P62324 BTG1
1
BTG1 [nucleoplasm]
(R-HSA-9620886)
0.488
2
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