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MCF2L [cytosol]
Stable Identifier
R-HSA-195070
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Dbs/MCF2L, Ost
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
MCF2L [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
MCF2L [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GEFs activate CDC42 (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
MCF2L [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GEFs activate RAC1 (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
MCF2L [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
MCF2L [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB GEFs activate RHOB (Homo sapiens)
RHOB GEFs [cytosol] (Homo sapiens)
MCF2L [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC GEFs activate RHOC (Homo sapiens)
RHOC GEFs [cytosol] (Homo sapiens)
MCF2L [cytosol] (Homo sapiens)
RHOG GTPase cycle (Homo sapiens)
RHOG GEFs activate RHOG (Homo sapiens)
RHOG GEFs [cytosol] (Homo sapiens)
MCF2L [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15068 MCF2L
Gene Names
MCF2L, KIAA0362, OST
Chain
chain:1-1137
Reference Genes
BioGPS Gene:23263 MCF2L
COSMIC (genes):MCF2L MCF2L
CTD Gene:23263 MCF2L
dbSNP Gene:23263 MCF2L
ENSEMBL:ENSG00000126217 MCF2L
ENSEMBL_homo_sapiens_GENE:ENSG00000126217.22 MCF2L
HGNC:14576 MCF2L
KEGG Gene (Homo sapiens):23263 MCF2L
Monarch:23263 MCF2L
NCBI Gene:23263 MCF2L
OMIM:609499 MCF2L
UCSC:O15068 MCF2L
Reference Transcript
RefSeq:NM_024979.4 MCF2L
RefSeq:NM_001320816.1 MCF2L
RefSeq:NM_001112732.2 MCF2L
RefSeq:NM_001320817.1 MCF2L
RefSeq:NM_001320815.1 MCF2L
Other Identifiers
11720740_a_at
11748456_a_at
11752006_a_at
11760028_at
1552743_3p_at
1552743_PM_at
1552743_at
1563809_PM_a_at
1563809_a_at
212935_PM_at
212935_at
23263
239636_PM_at
239636_at
3502260
3502275
3502276
3502277
3502278
3502283
3502295
3502296
3502307
3502313
3502330
3502341
3502342
3502343
3502345
3502346
3502348
3502351
3502352
3502353
3502354
3502355
3502356
3502357
3502359
3502360
3502361
3502362
3502363
3502364
3502365
3502366
3502368
3502369
3502370
3502371
3502372
3502378
3502379
3502383
3502384
3502385
3502386
3502387
3502388
3502389
3502390
3502391
3502392
3502393
3502395
3502397
3502409
3502410
35147_PM_at
35147_at
55268_at
7970194
A_14_P136825
A_19_P00807752
A_23_P434948
A_23_P88099
A_23_P88106
A_24_P390172
A_33_P3282018
A_33_P3317442
GE80400
GO:0005085
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005829
GO:0005886
GO:0008289
GO:0012505
GO:0016020
GO:0019898
GO:0023052
GO:0035025
GO:0035091
GO:0035556
GO:0048583
GO:0051056
GO:0098772
HMNXSV003003518
HMNXSV003019862
HMNXSV003027799
Hs.25515.0.S1_3p_at
Hs.25515.0.S1_3p_s_at
Hs.58399.0.A1_3p_at
Hs2.25515.1.A1_3p_at
Hs2.25515.1.A1_3p_s_at
ILMN_1736584
PH_hs_0025543
Participates
as a candidate of
RHOA GEFs [cytosol] (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
RHOG GEFs [cytosol] (Homo sapiens)
as a member of
RHOC GEFs [cytosol] (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
RHOB GEFs [cytosol] (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
Inferred To
cgef-1 [cytosol]
(Caenorhabditis elegans)
MCF2L [cytosol]
(Bos taurus)
MCF2L [cytosol]
(Canis familiaris)
MCF2L [cytosol]
(Gallus gallus)
MCF2L [cytosol]
(Sus scrofa)
Mcf2l [cytosol]
(Mus musculus)
Mcf2l [cytosol]
(Rattus norvegicus)
CG12183 [cytosol]
(Drosophila melanogaster)
mcf2l [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001307745.1
,
NP_001307746.1
,
NP_001106203.2
,
NP_001307744.1
,
NP_079255.4
OpenTargets
ENSG00000126217
HPA
ENSG00000126217-MCF2L
GeneCards
O15068
Ensembl
ENST00000375597
,
ENST00000535094
,
ENSP00000440374
,
ENSP00000364747
,
ENST00000375604
,
ENSP00000364758
,
ENSG00000126217
,
ENST00000397030
,
ENST00000375608
,
ENSP00000380225
,
ENSP00000397285
,
ENSP00000364754
,
ENST00000421756
PRO
O15068
Pharos - Targets
O15068
HMDB Protein
HMDBP08479
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