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Go!
RAC1 GEFs [cytosol]
Stable Identifier
R-HSA-9013168
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
cytosol
,
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GEFs activate RAC1 (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
7479768
Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family
Heisterkamp, N
,
Xu, X
,
Bokoch, GM
,
Groffen, J
,
Kaartinen, V
,
Chuang, TH
Proc. Natl. Acad. Sci. U.S.A.
1995
Participants
members
DOCK3 [cytosol]
(Homo sapiens)
FGD5 [cytosol]
(Homo sapiens)
GNA13 [plasma membrane]
(Homo sapiens)
PLEKHG6 [cytosol]
(Homo sapiens)
PREX1 [cytosol]
(Homo sapiens)
PREX2 [cytosol]
(Homo sapiens)
RASGRF2 [cytosol]
(Homo sapiens)
SWAP70 [cytosol]
(Homo sapiens)
TIAM2 [cytosol]
(Homo sapiens)
TRIO [cytosol]
(Homo sapiens)
VAV1 [cytosol]
(Homo sapiens)
VAV2 [cytosol]
(Homo sapiens)
candidates
ABR [cytosol]
(Homo sapiens)
ALS2 [cytosol]
(Homo sapiens)
ARHGEF4 [cytosol]
(Homo sapiens)
ARHGEF5 [cytosol]
(Homo sapiens)
ARHGEF6 [cytosol]
(Homo sapiens)
ARHGEF7 [cytosol]
(Homo sapiens)
ARHGEF10 [cytosol]
(Homo sapiens)
ARHGEF11 [cytosol]
(Homo sapiens)
ARHGEF15 [cytosol]
(Homo sapiens)
ARHGEF18 [cytosol]
(Homo sapiens)
ARHGEF19 [cytosol]
(Homo sapiens)
ARHGEF25 [cytosol]
(Homo sapiens)
ARHGEF39 [cytosol]
(Homo sapiens)
BCR [cytosol]
(Homo sapiens)
DEF6 [cytosol]
(Homo sapiens)
DOCK1 [cytosol]
(Homo sapiens)
DOCK2 [cytosol]
(Homo sapiens)
DOCK4 [cytosol]
(Homo sapiens)
DOCK5 [cytosol]
(Homo sapiens)
DOCK6 [cytosol]
(Homo sapiens)
DOCK7 [cytosol]
(Homo sapiens)
DOCK8 [cytosol]
(Homo sapiens)
DOCK9 [cytosol]
(Homo sapiens)
DOCK10 [cytosol]
(Homo sapiens)
DOCK11 [cytosol]
(Homo sapiens)
ECT2 [cytosol]
(Homo sapiens)
FARP1 [cytosol]
(Homo sapiens)
FARP2 [cytosol]
(Homo sapiens)
KALRN [cytosol]
(Homo sapiens)
MCF2 [cytosol]
(Homo sapiens)
MCF2L [cytosol]
(Homo sapiens)
NGEF [cytosol]
(Homo sapiens)
PLEKHG1 [cytosol]
(Homo sapiens)
PLEKHG2 [cytosol]
(Homo sapiens)
PLEKHG3 [cytosol]
(Homo sapiens)
PLEKHG4 [cytosol]
(Homo sapiens)
SOS1 [cytosol]
(Homo sapiens)
SOS2 [cytosol]
(Homo sapiens)
SPATA13 [cytosol]
(Homo sapiens)
TIAM1 [cytosol]
(Homo sapiens)
VAV3 [cytosol]
(Homo sapiens)
Inferred To
RAC1 GEFs [cytosol]
(Bos taurus)
RAC1 GEFs [cytosol]
(Caenorhabditis elegans)
RAC1 GEFs [cytosol]
(Canis familiaris)
RAC1 GEFs [cytosol]
(Danio rerio)
RAC1 GEFs [cytosol]
(Dictyostelium discoideum)
RAC1 GEFs [cytosol]
(Drosophila melanogaster)
RAC1 GEFs [cytosol]
(Gallus gallus)
RAC1 GEFs [cytosol]
(Mus musculus)
RAC1 GEFs [cytosol]
(Rattus norvegicus)
RAC1 GEFs [cytosol]
(Sus scrofa)
RAC1 GEFs [cytosol]
(Xenopus tropicalis)
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