MME [plasma membrane]

Stable Identifier
R-HSA-2022342
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Neprilysin, NEP_HUMAN, CD10
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P08473 MME
Gene Names
MME, EPN
Chain
initiator methionine:, chain:2-750
Reference Genes
BioGPS Gene:4311 MME
COSMIC (genes):MME MME
CTD Gene:4311 MME
dbSNP Gene:4311 MME
ENSEMBL:ENSG00000196549 MME
ENSEMBL_homo_sapiens_GENE:ENSG00000196549.13 MME
HGNC:7154 MME
KEGG Gene (Homo sapiens):4311 MME
Monarch:4311 MME
NCBI Gene:4311 MME
OMIM:120520 MME
UCSC:P08473 MME
Reference Transcript
Other Identifiers
11720022_a_at
11741562_a_at
11747693_a_at
11755860_a_at
1389_at
16947173
203434_PM_s_at
203434_s_at
203435_PM_s_at
203435_s_at
2648678
2648679
2648680
2648681
2648682
2648683
2648684
2648685
2648686
2648687
2648688
2648705
2648707
2648708
2648709
2648710
2648715
2648716
2648717
2648718
2648720
2648721
2648724
2648725
2648727
2648729
2648731
2648732
2648734
2648736
2648742
2648743
2648744
2648745
2648746
4311
8083494
A_23_P212061
A_24_P260101
A_33_P3290707
A_33_P3370094
GE58450
GO:0001786
GO:0001822
GO:0001890
GO:0003824
GO:0004175
GO:0004222
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005768
GO:0005769
GO:0005794
GO:0005802
GO:0005886
GO:0005903
GO:0005925
GO:0006508
GO:0006518
GO:0007611
GO:0008021
GO:0008233
GO:0008237
GO:0008238
GO:0008270
GO:0008289
GO:0009986
GO:0010814
GO:0010815
GO:0016020
GO:0016485
GO:0016787
GO:0019233
GO:0023052
GO:0030154
GO:0030163
GO:0030324
GO:0030424
GO:0030425
GO:0030667
GO:0031410
GO:0042277
GO:0042447
GO:0042803
GO:0043025
GO:0043226
GO:0043627
GO:0044306
GO:0045121
GO:0045202
GO:0046449
GO:0046872
GO:0048856
GO:0050435
GO:0050769
GO:0050877
GO:0051604
GO:0061837
GO:0070012
GO:0070062
GO:0071345
GO:0071492
GO:0071493
GO:0090399
GO:0097242
GO:0098793
GO:0140096
GO:0150094
GO:1900273
GO:1901612
HMNXSV003013972
Hs.1298.2.S1_3p_a_at
ILMN_1678170
ILMN_1696162
ILMN_1751943
ILMN_1786319
J03779_at
PH_hs_0023672
TC03000846.hg
g6042199_3p_a_at
Participates
as a component of
as a member of
Other forms of this molecule
MME [secretory granule membrane]
Inferred To
Nep6 [plasma membrane] (Drosophila melanogaster)
nep-13 [plasma membrane] (Caenorhabditis elegans)
Nepl21 [plasma membrane] (Drosophila melanogaster)
Nepl9 [plasma membrane] (Drosophila melanogaster)
nep-23 [plasma membrane] (Caenorhabditis elegans)
nep-26 [plasma membrane] (Caenorhabditis elegans)
Nepl11 [plasma membrane] (Drosophila melanogaster)
Nepl14 [plasma membrane] (Drosophila melanogaster)
MME [plasma membrane] (Bos taurus)
MME [plasma membrane] (Caenorhabditis elegans)
MME [plasma membrane] (Canis familiaris)
MME [plasma membrane] (Drosophila melanogaster)
MME [plasma membrane] (Gallus gallus)
MME [plasma membrane] (Mus musculus)
MME [plasma membrane] (Rattus norvegicus)
MME [plasma membrane] (Sus scrofa)
nep-10 [plasma membrane] (Caenorhabditis elegans)
nep-20 [plasma membrane] (Caenorhabditis elegans)
frma [plasma membrane] (Drosophila melanogaster)
Nepl19 [plasma membrane] (Drosophila melanogaster)
nep-8 [plasma membrane] (Caenorhabditis elegans)
nep-18 [plasma membrane] (Caenorhabditis elegans)
nep-24 [plasma membrane] (Caenorhabditis elegans)
Nepl3 [plasma membrane] (Drosophila melanogaster)
Nep5 [plasma membrane] (Drosophila melanogaster)
Nepl6 [plasma membrane] (Drosophila melanogaster)
mme [plasma membrane] (Xenopus tropicalis)
nep-4 [plasma membrane] (Caenorhabditis elegans)
Nepl15 [plasma membrane] (Drosophila melanogaster)
Nepl12 [plasma membrane] (Drosophila melanogaster)
Homologues of MME [plasma membrane] (Caenorhabditis elegans)
Homologues of MME [plasma membrane] (Drosophila melanogaster)
Nepl18 [plasma membrane] (Drosophila melanogaster)
nep-9 [plasma membrane] (Caenorhabditis elegans)
nep-17 [plasma membrane] (Caenorhabditis elegans)
nep-22 [plasma membrane] (Caenorhabditis elegans)
Nepl20 [plasma membrane] (Drosophila melanogaster)
Nepl8 [plasma membrane] (Drosophila melanogaster)
Nep7 [plasma membrane] (Drosophila melanogaster)
nep-25 [plasma membrane] (Caenorhabditis elegans)
nep-12 [plasma membrane] (Caenorhabditis elegans)
Nepl5 [plasma membrane] (Drosophila melanogaster)
Nepl7 [plasma membrane] (Drosophila melanogaster)
Nepl13 [plasma membrane] (Drosophila melanogaster)
Nepl16 [plasma membrane] (Drosophila melanogaster)
Nepl4 [plasma membrane] (Drosophila melanogaster)
Nepl10 [plasma membrane] (Drosophila melanogaster)
nep-3 [plasma membrane] (Caenorhabditis elegans)
Nepl17 [plasma membrane] (Drosophila melanogaster)
nep-6 [plasma membrane] (Caenorhabditis elegans)
goe [plasma membrane] (Drosophila melanogaster)
nep-16 [plasma membrane] (Caenorhabditis elegans)
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
ZINC - Metabolites
GeneCards
HPA
Ensembl
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (5)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P05067 APP  20 0.556 3
 UniProt:P04792 HSBP1  3 0.537 4
 UniProt:Q8WZA1 POMGNT1  6 0.527 2
 UniProt:A0PJW6 TMEM223  1 0.527 2
 UniProt:P21926 CD9  4 0.499 6
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