5S-HpETE is reduced to 5S-HETE by GPX1/2/4

Stable Identifier
R-HSA-2161946
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Glutathione peroxidase 1 (GPX1) (Bryant et al. 1982, Sutherland et al. 2001), 2 (GPX2) (Chu et al. 1993), and 4 (Bryant et al. 1982, Sutherland et al. 2001) reduce 5-hydroperoxyeicosatetraenoic acid (5-HpETE) to 5-hydroxyeicosatetraenoic acid (5-HETE) in the presence of glutathione (GSH). This reaction is inferred from the event in rabbit involving the protein GPX1 (Chiba et al. 1999).

Participants
Participates
Catalyst Activity

glutathione peroxidase activity of GPX1/2/4 [cytosol]

Inferred From
Cross References
Rhea
Authored
Reviewed
Created
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