Reactome | TSPO [mitochondrial outer membrane]

TSPO [mitochondrial outer membrane]

Stable Identifier

R-HSA-2980957

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

Translocator protein, TSPOA_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P30536 TSPO

Gene Names

TSPO, PBRS, BZRP, MBR

Chain

initiator methionine:, chain:2-169

Reference Genes

BioGPS Gene:706 TSPO

COSMIC (genes):TSPO TSPO

CTD Gene:706 TSPO

dbSNP Gene:706 TSPO

ENSEMBL:ENSG00000100300 TSPO

HGNC:1158 TSPO

Monarch:706 TSPO

NCBI Gene:706 TSPO

OMIM:109610 TSPO

UCSC:P30536 TSPO

Reference Transcript

Other Identifiers

11716614_a_at

11745503_x_at

11757058_x_at

16930954

202096_PM_s_at

202096_s_at

32806_at

3947628

3947629

3947630

3947634

3947635

3947636

3947637

3947639

3947640

3947641

3947643

3947644

706

8073612

A_24_P134526

A_33_P3251148

GE80941

GO:0005215

GO:0005497

GO:0005515

GO:0005739

GO:0005741

GO:0005783

GO:0005829

GO:0006626

GO:0006629

GO:0006694

GO:0006700

GO:0006783

GO:0006811

GO:0006820

GO:0006821

GO:0006869

GO:0008202

GO:0008289

GO:0008347

GO:0008503

GO:0009410

GO:0010042

GO:0010266

GO:0014012

GO:0015485

GO:0015918

GO:0016020

GO:0030325

GO:0031397

GO:0031966

GO:0032374

GO:0032570

GO:0032720

GO:0033574

GO:0042127

GO:0042632

GO:0043065

GO:0043226

GO:0043231

GO:0044325

GO:0045019

GO:0048265

GO:0048266

GO:0048678

GO:0048856

GO:0048870

GO:0050810

GO:0051901

GO:0051928

GO:0060089

GO:0060242

GO:0060252

GO:0060253

GO:0062100

GO:0070062

GO:0071222

GO:0071294

GO:0071476

GO:0072655

GO:0072656

GO:0120020

GO:1901525

GO:1903579

GO:1905144

GO:2000379

GO:2000853

HMNXSV003047662

ILMN_1681679

ILMN_2260991

ILMN_2349658

L21954_at

PH_hs_0000028

TC22000362.hg

g6382068_3p_a_at

Participates

as a component of

TSPO:BZRAP1 [mitochondrial outer membrane] (Homo sapiens)

Inferred To

Tspo [mitochondrial outer membrane] (Drosophila melanogaster)

Tspo [mitochondrial outer membrane] (Mus musculus)

Tspo [mitochondrial outer membrane] (Rattus norvegicus)

tspo-1 [mitochondrial outer membrane] (Caenorhabditis elegans)

TSPO [mitochondrial outer membrane] (Canis familiaris)

TSPO [mitochondrial outer membrane] (Gallus gallus)

TSPO [mitochondrial outer membrane] (Sus scrofa)

Cross References

Guide to Pharmacology - Targets

2879

ENSEMBL

ENSP00000328973, ENST00000337554, ENST00000396265, ENSP00000338004, ENSP00000379563, ENST00000329563

OpenTargets

ENSG00000100300

HPA

ENSG00000100300-TSPO

ZINC - Substances

TSPOA_HUMAN

ZINC target

P30536

Pharos - Targets

P30536

ZINC - Predictions - Purchasable

TSPOA_HUMAN

HMDB Protein

HMDBP02723

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.781	7
UniProt:P29762 CRABP1	1	SUMO-K-CRABP1 [cytosol] (R-HSA-5334807)	0.589	2
UniProt:P15151 PVR	1	PVR [plasma membrane] (R-HSA-420600)	0.556	3
UniProt:Q8IUN9 CLEC10A	1	CLEC10A [plasma membrane] (R-HSA-1472863)	0.556	3
UniProt:A8MZ59 LEUTX	1	LEUTX [nucleoplasm] (R-HSA-9817277)	0.556	3
UniProt:P32942 ICAM3	1	ICAM3 [plasma membrane] (R-HSA-197682)	0.556	3
UniProt:Q68D85 NCR3LG1	1	NCR3LG1 [plasma membrane] (R-HSA-5683240)	0.556	3
UniProt:Q8N695 SLC5A8	1	SLC5A8 [plasma membrane] (R-HSA-429769)	0.527	2