Reactome | TMSB4X [platelet alpha granule lumen]

TMSB4X [platelet alpha granule lumen]

Stable Identifier

R-HSA-349758

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

platelet alpha granule lumen

Synonyms

Thymosin beta-4

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P62328 TMSB4X

Gene Names

TMSB4X, TB4X, THYB4, TMSB4

Chain

initiator methionine:, chain:2-44, peptide:2-5

Reference Genes

BioGPS Gene:7114 TMSB4X

COSMIC (genes):TMSB4X TMSB4X

CTD Gene:7114 TMSB4X

dbSNP Gene:7114 TMSB4X

ENSEMBL:ENSG00000205542 TMSB4X

ENSEMBL_homo_sapiens_GENE:ENSG00000205542.11 TMSB4X

HGNC:11881 TMSB4X

KEGG Gene (Homo sapiens):7114 TMSB4X

Monarch:7114 TMSB4X

NCBI Gene:7114 TMSB4X

OMIM:300159 TMSB4X

UCSC:P62328 TMSB4X

Reference Transcript

RefSeq:NM_021109.3 TMSB4X

Other Identifiers

11753735_x_at

11754315_x_at

17101543

216438_PM_s_at

216438_s_at

2408958

2777881

2777882

2777883

2777884

2777885

2777886

31557_at

3909336

3969140

3969141

3969142

3969143

3969144

3969145

3969148

3969149

3969150

3969151

4073679

51008_f_at

7114

77035_at

8067007

8101774

8158240

8166072

A_14_P118791

A_23_P399201

A_24_P143189

GE82589

GO:0003723

GO:0003779

GO:0003785

GO:0005515

GO:0005576

GO:0005634

GO:0005737

GO:0005829

GO:0005856

GO:0006954

GO:0007010

GO:0007015

GO:0008092

GO:0019899

GO:0023052

GO:0030334

GO:0031093

GO:0031410

GO:0033209

GO:0042989

GO:0043124

GO:0043226

GO:0043536

GO:0048870

GO:0050728

GO:0055085

GO:0055086

GO:0065003

GO:0140311

GO:0140313

GO:1901135

GO:1905273

GO:2001028

GO:2001171

HMNXSV003001635

ILMN_1683271

ILMN_2222688

M17733_at

TC04001384.hg

TC0X000053.hg

Participates

as a member of

Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)

Other forms of this molecule

TMSB4X [extracellular region]

Inferred To

Tmsb4x [platelet alpha granule lumen] (Mus musculus)

Tmsb4x [platelet alpha granule lumen] (Rattus norvegicus)

TMSB4X [platelet alpha granule lumen] (Bos taurus)

TMSB4X [platelet alpha granule lumen] (Gallus gallus)

TMSB4 [platelet alpha granule lumen] (Sus scrofa)

LOC102152706 [platelet alpha granule lumen] (Canis familiaris)

tmsb4x [platelet alpha granule lumen] (Danio rerio)

tmsb4x [platelet alpha granule lumen] (Xenopus tropicalis)

Cross References

RefSeq

NP_066932.1

OpenTargets

ENSG00000205542

GeneCards

P62328

HPA

ENSG00000205542-TMSB4X

Ensembl

ENST00000380636, ENST00000380635, ENST00000380633, ENST00000451311, ENSP00000414376, ENSP00000370007, ENSP00000370009, ENSP00000370010, ENSG00000205542

PRO

P62328

Pharos - Targets

P62328

PDB

3TU5, 4PL7, 4PL8

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P40692 MLH1	3	MLH1 S252* [nucleoplasm] (R-HSA-5444526) MLH1 H329P [nucleoplasm] (R-HSA-5444512) MLH1 [nucleoplasm] (R-HSA-912495)	0.733	16
UniProt:Q9ULX6 AKAP8L	1	AKAP8L [nucleoplasm] (R-HSA-9821364)	0.556	3
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3

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