Translocation of RIAM to plasma membrane

Stable Identifier
R-HSA-354060
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Upon the production of activated Rap1A at the plasma membrane, RIAM interacts with Rap1A-GTP with its N-ter RA domain, and with its C-ter PH domain it interacts with PIP2.
Literature References
PubMed ID Title Journal Year
16757337 Rap1 regulation of RIAM and cell adhesion

Boussiotis, VA, Lafuente, E

Methods Enzymol 2006
17624957 Platelet integrins and immunoreceptors

Kasirer-Friede, A, Kahn, ML, Shattil, SJ

Immunol Rev 2007
15469846 RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion

Constantine, E, Krause, M, van Puijenbroek, AA, Springer, TA, Lafuente, EM, Gertler, FB, Carman, CV, Freeman, GJ, Berezovskaya, A, Boussiotis, VA

Dev Cell 2004
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