DOLK M1I [endoplasmic reticulum membrane]

Stable Identifier
R-HSA-4755593
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Dolichol kinase, DOLK_HUMAN
Icon
DOLK M1I [endoplasmic reticulum membrane] icon
DOLK M1I [endoplasmic reticulum membrane] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:Q9UPQ8 DOLK
Gene Names
DOLK, KIAA1094, TMEM15, UNQ2422/PRO4980
Chain
chain:1-538
Reference Genes
BioGPS Gene:22845 DOLK
COSMIC (genes):DOLK DOLK
CTD Gene:22845 DOLK
dbSNP Gene:22845 DOLK
ENSEMBL:ENSG00000175283 DOLK
HGNC:23406 DOLK
KEGG:hsa:22845 DOLK
Monarch:22845 DOLK
NCBI Gene:22845 DOLK
OMIM:610746 DOLK
UCSC:Q9UPQ8 DOLK
Reference Transcript
Other Identifiers
11724825_a_at
11752810_a_at
17098974
204488_PM_at
204488_at
22845
3226790
3226791
3226792
3226793
3226794
3226795
35403_at
8164515
A_23_P10870
GE53743
GO:0003824
GO:0004168
GO:0005515
GO:0005783
GO:0005789
GO:0006486
GO:0006489
GO:0006629
GO:0016020
GO:0016301
GO:0016740
GO:0035268
GO:0043048
GO:0043226
HMNXSV003025537
ILMN_1753627
PH_hs_0026195
TC09001641.hg
g7662481_3p_at
Participates
as a member of
Other forms of this molecule
DOLK [endoplasmic reticulum membrane]
DOLK H408D [endoplasmic reticulum membrane]
DOLK C99S [endoplasmic reticulum membrane]
DOLK W304C [endoplasmic reticulum membrane]
DOLK Y441S [endoplasmic reticulum membrane]
Modified Residues
Name
L-methionine 1 replaced with L-isoleucine
Coordinate
1
PsiMod
L-methionine removal [MOD:01643]
A protein modification that effectively removes or replaces an L-methionine.
L-isoleucine residue [MOD:00019]
A protein modification that effectively converts a source amino acid residue to an L-isoleucine.
Disease
Cross References
OpenTargets
ENSEMBL
HPA
PRO
Pharos - Targets
Orphanet
HMDB Protein
Interactors (25)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9HCJ2 LRC4C      0.742 5
 UniProt:P17658 KCNA6  1 0.742 6
 UniProt:Q92838 EDA  1 0.718 6
 UniProt:P22001 KCNA3  1 0.718 6
 UniProt:Q96HE8 TMM80      0.556 3
 UniProt:Q92536 SLC7A6  1 0.556 3
 UniProt:Q09470 KCNA1  1 0.556 7
 UniProt:Q5JX71 F209A      0.556 3
 UniProt:Q8TED1 GPX8  1 0.556 3
 UniProt:Q96BA8 CREB3L1  7 0.556 3
 UniProt:Q16322 KCNA10  1 0.556 5
 UniProt:Q96B21 TM45B      0.556 3
 UniProt:Q92624 APBP2      0.556 3
 UniProt:Q9H7M9 VISTA      0.556 3
 UniProt:P48165 GJA8  1 0.556 3
 UniProt:Q9H9P2 CHODL      0.556 3
 UniProt:Q8TBE3 FNDC9      0.556 3
 UniProt:P11912 CD79A  2 0.556 3
 UniProt:Q8TBG9 SYNPR      0.556 3
 UniProt:Q9NZQ7 CD274  1 0.527 2
 UniProt:Q8WVE6 TM171      0.527 2
 UniProt:Q8TD20 SLC2A12  1 0.527 2
 UniProt:P35414 APLNR  1 0.527 2
 UniProt:P25090 FPR2  4 0.527 2
 UniProt:P22460 KCNA5  1 0.527 2
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