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LPPR1 [plasma membrane]
Stable Identifier
R-HSA-6797625
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Lipid phosphate phosphatase-related protein type 1, LPPR1_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Lysosphingolipid and LPA receptors (Homo sapiens)
LRPP4(LRPP1-3,5) hydrolyse LPA (Homo sapiens)
LPPR4(LPPR1-3,5) [plasma membrane] (Homo sapiens)
LPPR1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TBJ4 PLPPR1
Gene Names
PLPPR1, LPPR1, PRG3
Chain
chain:1-325
Reference Genes
BioGPS Gene:54886 PLPPR1
COSMIC (genes):PLPPR1 PLPPR1
CTD Gene:54886 PLPPR1
dbSNP Gene:54886 PLPPR1
ENSEMBL:ENSG00000148123 PLPPR1
ENSEMBL_homo_sapiens_GENE:ENSG00000148123.15 PLPPR1
ENSEMBL_homo_sapiens_GENE:ENSG00000276539.4 PLPPR1
HGNC:25993 PLPPR1
KEGG Gene (Homo sapiens):54886 PLPPR1
Monarch:54886 PLPPR1
NCBI Gene:54886 PLPPR1
OMIM:619590 PLPPR1
UCSC:Q8TBJ4 PLPPR1
Reference Transcript
RefSeq:NM_017753.2 PLPPR1
RefSeq:NM_207299.1 PLPPR1
Other Identifiers
11726598_a_at
11726599_a_at
17087615
219732_PM_at
219732_at
3182331
3182332
3182333
3182347
3182348
3182349
3182358
3182360
3182361
3182369
3182370
3182371
3182372
3182373
49989_at
54886
8156923
A_14_P104855
A_14_P111675
A_23_P259707
GE55437
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005886
GO:0006629
GO:0006644
GO:0007165
GO:0007399
GO:0008195
GO:0016020
GO:0016787
GO:0023052
GO:0042995
GO:0043005
GO:0043226
GO:0046839
GO:0048856
HMNXSV003049058
ILMN_1753026
ILMN_1780576
ILMN_2234930
PH_hs_0024356
TC09000515.hg
g8923280_3p_at
Participates
as a candidate of
LPPR4(LPPR1-3,5) [plasma membrane] (Homo sapiens)
Inferred To
LPPR1 [plasma membrane]
(Dictyostelium discoideum)
Plppr1 [plasma membrane]
(Mus musculus)
Plppr1 [plasma membrane]
(Rattus norvegicus)
plpr-1 [plasma membrane]
(Caenorhabditis elegans)
LPP1 [plasma membrane]
(Saccharomyces cerevisiae)
DPP1 [plasma membrane]
(Saccharomyces cerevisiae)
dpp1 [plasma membrane]
(Schizosaccharomyces pombe)
plppr1 [plasma membrane]
(Xenopus tropicalis)
Homologues of LPPR1 [plasma membrane]
(Dictyostelium discoideum)
Homologues of LPPR1 [plasma membrane]
(Saccharomyces cerevisiae)
PLPPR1 [plasma membrane]
(Bos taurus)
PLPPR1 [plasma membrane]
(Canis familiaris)
PLPPR1 [plasma membrane]
(Gallus gallus)
PLPPR1 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_060223.2
,
NP_997182.1
OpenTargets
ENSG00000148123
HPA
ENSG00000148123-PLPPR1
GeneCards
Q8TBJ4
Ensembl
ENSP00000477959
,
ENST00000614834
,
ENSP00000478338
,
ENSG00000276539
,
ENST00000374874
,
ENSG00000148123
,
ENST00000611695
,
ENST00000395056
,
ENSP00000364008
,
ENSP00000378496
PRO
Q8TBJ4
Pharos - Targets
Q8TBJ4
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P37173 TGFBR2
9
TGFBR2 Y470D [plasma membrane]
(R-HSA-3640905)
TGFBR2 E526Q [plasma membrane]
(R-HSA-3645770)
TGFBR2 D522N [plasma membrane]
(R-HSA-3640907)
TGFBR2 R528H [plasma membrane]
(R-HSA-3640894)
TGFBR2 R528C [plasma membrane]
(R-HSA-3640899)
TGFBR2 K128Afs*3 [cytosol]
(R-HSA-3642173)
TGFBR2 K128Sfs*35 [cytosol]
(R-HSA-3642166)
NEDD8-K556,K567-TGFBR2 [plasma membrane]
(R-HSA-4332222)
TGFBR2 [plasma membrane]
(R-HSA-170842)
0.556
3
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:Q9Y6X1 SERP1
2
SERP1 [endoplasmic reticulum membrane]
(R-HSA-381045)
SERP1 [cytosol]
(R-HSA-5250574)
0.556
3
UniProt:P50454 SERPINH1
1
SERPINH1 [endoplasmic reticulum lumen]
(R-HSA-2127480)
0.556
3
UniProt:P16284 PECAM1
5
PECAM1 [platelet alpha granule membrane]
(R-HSA-61489)
PECAM1 [plasma membrane]
(R-HSA-114686)
PECAM1 [secretory granule membrane]
(R-HSA-6804778)
p-Y663,Y686-PECAM1(27-?) [plasma membrane]
(R-HSA-210007)
p-Y713-PECAM1 [plasma membrane]
(R-HSA-9860772)
0.556
3
UniProt:Q9BRI3 SLC30A2
2
SLC30A2 [endosome membrane]
(R-HSA-435363)
SLC30A2 [synaptic vesicle membrane]
(R-HSA-4084714)
0.556
3
UniProt:Q12846 STX4
4
STX4 [phagocytic vesicle membrane]
(R-HSA-2029044)
STX4 [plasma membrane]
(R-HSA-181519)
STX4 [cytosol]
(R-HSA-114505)
p-STX4 [cytosol]
(R-HSA-114681)
0.527
2
UniProt:O00186 STXBP3
4
p-Y521-STXBP3 [plasma membrane]
(R-HSA-2263472)
STXBP3 [plasma membrane]
(R-HSA-2263473)
p-STXBP3 [cytosol]
(R-HSA-114680)
STXBP3 [cytosol]
(R-HSA-114682)
0.527
2
UniProt:P61224 RAP1B
2
RAP1B [azurophil granule membrane]
(R-HSA-6804972)
RAP1B [plasma membrane]
(R-HSA-377590)
0.527
2
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