Reactome | ALDOC [secretory granule lumen]

ALDOC [secretory granule lumen]

Stable Identifier

R-HSA-6801483

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

secretory granule lumen

Synonyms

Fructose-bisphosphate aldolase C , Brain-type aldolase

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P09972 ALDOC

Gene Names

ALDOC, ALDC

Chain

chain:1-364

Reference Genes

BioGPS Gene:230 ALDOC

COSMIC (genes):ALDOC ALDOC

CTD Gene:230 ALDOC

dbSNP Gene:230 ALDOC

ENSEMBL:ENSG00000109107 ALDOC

ENSEMBL_homo_sapiens_GENE:ENSG00000109107.14 ALDOC

HGNC:418 ALDOC

KEGG Gene (Homo sapiens):230 ALDOC

Monarch:230 ALDOC

NCBI Gene:230 ALDOC

OMIM:103870 ALDOC

UCSC:P09972 ALDOC

Reference Transcript

Other Identifiers

11724461_a_at

11724462_x_at

11747079_x_at

11751153_a_at

11751154_x_at

16842659

202022_PM_at

202022_at

230

3750771

3750772

3750773

3750774

3750776

3750777

3750778

3750779

3750780

3750781

3750783

3750784

40107_at

8013660

A_23_P78108

GE54504

GO:0003824

GO:0004332

GO:0005515

GO:0005576

GO:0005615

GO:0005829

GO:0005856

GO:0005975

GO:0006000

GO:0006091

GO:0006094

GO:0006096

GO:0008092

GO:0016829

GO:0030154

GO:0030388

GO:0030855

GO:0031410

GO:0034774

GO:0043226

GO:0048856

GO:0055086

GO:0070062

GO:1901135

GO:1904724

GO:1904813

HMNXSV003038908

ILMN_1755974

PH_hs_0009353

PH_hs_0040288

TC17001301.hg

X05196_at

g4885062_3p_at

Participates

as a member of

Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)

Other forms of this molecule

ALDOC [ficolin-1-rich granule lumen]

ALDOC [extracellular region]

ALDOC [tertiary granule lumen]

ALDOC [cytosol]

Inferred To

Homologues of ALDOC [secretory granule lumen] (Caenorhabditis elegans)

Homologues of ALDOC [secretory granule lumen] (Drosophila melanogaster)

Ald2 [secretory granule lumen] (Drosophila melanogaster)

aldoc [secretory granule lumen] (Xenopus tropicalis)

ALDOC [secretory granule lumen] (Bos taurus)

ALDOC [secretory granule lumen] (Caenorhabditis elegans)

ALDOC [secretory granule lumen] (Canis familiaris)

ALDOC [secretory granule lumen] (Danio rerio)

ALDOC [secretory granule lumen] (Dictyostelium discoideum)

ALDOC [secretory granule lumen] (Drosophila melanogaster)

ALDOC [secretory granule lumen] (Gallus gallus)

ALDOC [secretory granule lumen] (Mus musculus)

ALDOC [secretory granule lumen] (Plasmodium falciparum)

ALDOC [secretory granule lumen] (Rattus norvegicus)

ALDOC [secretory granule lumen] (Sus scrofa)

Cross References

RefSeq

XP_005258006.1, NP_005156.1, XP_011522858.1

OpenTargets

ENSG00000109107

GeneCards

P09972

HPA

ENSG00000109107-ALDOC

Ensembl

ENSP00000226253, ENSG00000109107, ENSP00000378731, ENST00000226253, ENST00000395321

PRO

P09972

Pharos - Targets

P09972

HMDB Protein

HMDBP00979

PDB

1XFB

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.64	8

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