Reactome | RAB3IL1 [cytosol]

RAB3IL1 [cytosol]

Stable Identifier

R-HSA-8875296

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Guanine nucleotide exchange factor for Rab-3A, R3GEF_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8TBN0 RAB3IL1

Gene Names

RAB3IL1

Chain

chain:1-382

Reference Genes

BioGPS Gene:5866 RAB3IL1

COSMIC (genes):RAB3IL1 RAB3IL1

CTD Gene:5866 RAB3IL1

dbSNP Gene:5866 RAB3IL1

ENSEMBL:ENSG00000167994 RAB3IL1

ENSEMBL_homo_sapiens_GENE:ENSG00000167994.13 RAB3IL1

HGNC:9780 RAB3IL1

KEGG Gene (Homo sapiens):5866 RAB3IL1

Monarch:5866 RAB3IL1

NCBI Gene:5866 RAB3IL1

UCSC:Q8TBN0 RAB3IL1

Reference Transcript

Other Identifiers

11745338_a_at

16739192

219579_PM_at

219579_at

3375616

3375617

3375618

3375620

3375622

3375623

3375624

3375626

3375627

3375628

3375629

3375630

3375631

3375632

3375633

3375634

3375635

3375636

47507_at

5866

7948643

A_19_P00811063

A_23_P75800

GE62050

GO:0005085

GO:0005515

GO:0005829

GO:0006887

GO:0015031

GO:0016192

GO:0031410

GO:0042802

GO:0043226

GO:0070319

GO:0098772

HMNXSV003016518

ILMN_1741632

PH_hs_0001317

TC11001859.hg

g7019512_3p_s_at

Participates

as a candidate of

RAB8 GEFs [cytosol] (Homo sapiens)

as a member of

RAB3 GEFs [cytosol] (Homo sapiens)

Inferred To

SEC2 [cytosol] (Saccharomyces cerevisiae)

sec2 [cytosol] (Schizosaccharomyces pombe)

RAB3IL1 [cytosol] (Bos taurus)

RAB3IL1 [cytosol] (Caenorhabditis elegans)

RAB3IL1 [cytosol] (Canis familiaris)

RAB3IL1 [cytosol] (Gallus gallus)

RAB3IL1 [cytosol] (Sus scrofa)

Rab3il1 [cytosol] (Mus musculus)

Rab3il1 [cytosol] (Rattus norvegicus)

rab3il1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_037533.2, NP_001258615.1

OpenTargets

ENSG00000167994

GeneCards

Q8TBN0

HPA

ENSG00000167994-RAB3IL1

Ensembl

ENSP00000378313, ENSG00000167994, ENST00000301773, ENST00000394836, ENSP00000301773

PRO

Q8TBN0

Pharos - Targets

Q8TBN0

PDB

4LI0

HMDB Protein

HMDBP11494

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96QF0 RAB3IP	1	RAB3IP [cytosol] (R-HSA-5617610)	0.855	10
UniProt:Q16623 STX1A	5	STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.556	3
UniProt:P20336 RAB3A	9	GGC-RAB3A [secretory granule membrane] (R-HSA-8875319) GGC-RAB3A [cytosol] (R-HSA-8870429) RAB3A [cytosol] (R-HSA-8870410) RAB3A [secretory granule membrane] (R-HSA-6804968) RAB3A [clathrin-sculpted acetylcholine transport vesicle membrane] (R-HSA-379365) RAB3A [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-210466) RAB3A [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-917743) RAB3A [plasma membrane] (R-HSA-210461) RAB3A [clathrin-sculpted monoamine transport vesicle membrane] (R-HSA-372512)	0.556	3
UniProt:Q9UPW6 SATB2	2	polySUMO3-K233,K350-SATB2 [nucleoplasm] (R-HSA-4615865) SATB2 [nucleoplasm] (R-HSA-4615944)	0.556	3
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.488	2

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