Reactome | UBE2V2 [cytosol]

UBE2V2 [cytosol]

Stable Identifier

R-HSA-947624

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin-conjugating enzyme E2 variant 2, UB2V2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q15819 UBE2V2

Gene Names

UBE2V2, MMS2, UEV2

Chain

initiator methionine:, chain:2-145

Reference Genes

BioGPS Gene:7336 UBE2V2

COSMIC (genes):UBE2V2 UBE2V2

CTD Gene:7336 UBE2V2

dbSNP Gene:7336 UBE2V2

ENSEMBL:ENSG00000169139 UBE2V2

ENSEMBL_homo_sapiens_GENE:ENSG00000169139.12 UBE2V2

HGNC:12495 UBE2V2

KEGG Gene (Homo sapiens):7336 UBE2V2

Monarch:7336 UBE2V2

NCBI Gene:7336 UBE2V2

OMIM:603001 UBE2V2

UCSC:Q15819 UBE2V2

Reference Transcript

RefSeq:NM_003350.2 UBE2V2

Other Identifiers

11727093_s_at

11754112_a_at

209096_PM_at

209096_at

228734_PM_at

228734_at

230411_PM_at

230411_at

3097218

3097222

3097223

3097226

3097227

3097228

3097229

3097230

3097232

37750_at

52701_at

53558_at

7336

8146379

83354_r_at

A_33_P3333810

GE54423

GO:0000209

GO:0000729

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0006281

GO:0006282

GO:0006301

GO:0016567

GO:0031372

GO:0036211

GO:0042275

GO:0043226

GO:0070062

GO:0070534

GO:1902523

GO:2000781

HMNXSV003035753

Hs.247848.0.S1_3p_s_at

Hs.30662.0.A1_3p_at

Hs.43569.0.A1_3p_at

ILMN_1770515

ILMN_2076567

PH_hs_0029906

TC08000348.hg

U62136_at

g4775663_3p_at

Participates

as a candidate of

E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)

Other forms of this molecule

UBE2V2 [nucleoplasm]

Inferred To

Ube2v2 [cytosol] (Mus musculus)

Ube2v2 [cytosol] (Rattus norvegicus)

Uev1A [cytosol] (Drosophila melanogaster)

spm2 [cytosol] (Schizosaccharomyces pombe)

ube2v2 [cytosol] (Danio rerio)

MMS2 [cytosol] (Saccharomyces cerevisiae)

LOC119868036 [cytosol] (Canis familiaris)

uev-1 [cytosol] (Caenorhabditis elegans)

UBE2V2 [cytosol] (Bos taurus)

UBE2V2 [cytosol] (Gallus gallus)

UBE2V2 [cytosol] (Plasmodium falciparum)

ube2v [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_003341.1

OpenTargets

ENSG00000169139

HPA

ENSG00000169139-UBE2V2

GeneCards

Q15819

Ensembl

ENSP00000428209, ENSG00000169139, ENST00000523111

PRO

Q15819

Pharos - Targets

Q15819

PDB

5AIT, 3VON, 1J74, 7BBF, 4ONN, 1J7D, 7BBD, 4NRG, 8WR5, 4NR3, 4NRI, 4ORH, 4ONM, 1ZGU, 4ONL

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61088 UBE2N	5	Ub-C87-UBE2N [nucleoplasm] (R-HSA-8943013) K63polyUb-C87-UBE2N [nucleoplasm] (R-HSA-6790511) UBE2N [nucleoplasm] (R-HSA-5682541) Ub-C87-UBE2N [cytosol] (R-HSA-8864210) UBE2N [cytosol] (R-HSA-206072)	0.811	6
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:Q14527 HLTF	1	HLTF [nucleoplasm] (R-HSA-8855007)	0.462	2

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