FOXO-mediated transcription

Stable Identifier
R-HSA-9614085
DOI
10.3180/R-HSA-9614085.1
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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FOXO-mediated transcription
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The family of FOXO transcription factors includes FOXO1, FOXO3, FOXO4 and FOXO6. FOXO transcription factors integrate pathways that regulate cell survival, growth, differentiation and metabolism in response to environmental changes, such as growth factor deprivation, starvation and oxidative stress (reviewed by Accili and Arden 2004, Calnan and Brunet 2008, Eijkelenboom and Burgering 2013).
Literature References
PubMed ID Title Journal Year
15137936 FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

Accili, D, Arden, KC

Cell 2004
23325358 FOXOs: signalling integrators for homeostasis maintenance

Burgering, BM, Eijkelenboom, A

Nat. Rev. Mol. Cell Biol. 2013
18391970 The FoxO code

Brunet, A, Calnan, DR

Oncogene 2008
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Orthologous Events
FOXO-mediated transcription (Bos taurus)
FOXO-mediated transcription (Caenorhabditis elegans)
FOXO-mediated transcription (Canis familiaris)
FOXO-mediated transcription (Danio rerio)
FOXO-mediated transcription (Drosophila melanogaster)
FOXO-mediated transcription (Gallus gallus)
FOXO-mediated transcription (Mus musculus)
FOXO-mediated transcription (Rattus norvegicus)
FOXO-mediated transcription (Sus scrofa)
FOXO-mediated transcription (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2018-10-11)
Reviewed
Bertaggia, E  (2018-10-26)
Donlon, T  (2018-10-17)
Created
Orlic-Milacic, M  (2018-07-23)
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