FOXO-mediated transcription

Stable Identifier
R-HSA-9614085
DOI
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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The family of FOXO transcription factors includes FOXO1, FOXO3, FOXO4 and FOXO6. FOXO transcription factors integrate pathways that regulate cell survival, growth, differentiation and metabolism in response to environmental changes, such as growth factor deprivation, starvation and oxidative stress (reviewed by Accili and Arden 2004, Calnan and Brunet 2008, Eijkelenboom and Burgering 2013).
Literature References
PubMed ID Title Journal Year
15137936 FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

Accili, D, Arden, KC

Cell 2004
23325358 FOXOs: signalling integrators for homeostasis maintenance

Burgering, BM, Eijkelenboom, A

Nat. Rev. Mol. Cell Biol. 2013
18391970 The FoxO code

Brunet, A, Calnan, DR

Oncogene 2008
Participants
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Orthologous Events
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