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p-S621 RAF1 CR2 mutants [cytosol]
Stable Identifier
R-HSA-9656159
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Oncogenic MAPK signaling (Homo sapiens)
Signaling by RAF1 mutants (Homo sapiens)
CR2 RAF1 mutants don't bind YWHAB (Homo sapiens)
p-S621 RAF1 CR2 mutants [cytosol] (Homo sapiens)
Phosphorylation of RAF1 mutants (Homo sapiens)
p21 RAS:GTP:RAF1 mutant heterodimers [plasma membrane] (Homo sapiens)
RAF1 mutants [cytosol] (Homo sapiens)
p-S621 RAF1 CR2 mutants [cytosol] (Homo sapiens)
RAF1 mutants show enhanced heterodimerization with BRAF (Homo sapiens)
RAF1 mutants [cytosol] (Homo sapiens)
p-S621 RAF1 CR2 mutants [cytosol] (Homo sapiens)
p21 RAS:GTP:RAF1 mutant heterodimers [plasma membrane] (Homo sapiens)
RAF1 mutants [cytosol] (Homo sapiens)
p-S621 RAF1 CR2 mutants [cytosol] (Homo sapiens)
Participants
members
p-S621-RAF1 S257L [cytosol]
(Homo sapiens)
p-S621-RAF1 S259F [cytosol]
(Homo sapiens)
p-S621-RAF1 S259T [cytosol]
(Homo sapiens)
p-S621-RAF1 P261A [cytosol]
(Homo sapiens)
p-S621-RAF1 P261L [cytosol]
(Homo sapiens)
p-S621-RAF1 P261S [cytosol]
(Homo sapiens)
p-S621-RAF1 P261T [cytosol]
(Homo sapiens)
p-S621-RAF1 N262K [cytosol]
(Homo sapiens)
candidates
p-S621-RAF1 R256S [cytosol]
(Homo sapiens)
p-S621-RAF1 S259P [cytosol]
(Homo sapiens)
p-S621-RAF1 T260I [cytosol]
(Homo sapiens)
p-S621-RAF1 T260R [cytosol]
(Homo sapiens)
p-S621-RAF1 P261R [cytosol]
(Homo sapiens)
p-S621-RAF1 V263A [cytosol]
(Homo sapiens)
Participates
as an input of
CR2 RAF1 mutants don't bind YWHAB (Homo sapiens)
as a member of
RAF1 mutants [cytosol] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
Noonan syndrome
DOID:3490
Turner's phenotype, karyotype normal (disorder)
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