proHPSE:SDC1 is delivered to lysosomes

Stable Identifier
R-HSA-9792581
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
lysosomal lumen, plasma membrane
ReviewStatus
5/5
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proHPSE:SDC1 is delivered to lysosomes
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The proHPSE:syndecan1 complex associated with the plasma membrane is internalized by clathrin-dependent endocytosis) and delivered to lysosomes (Shteingauz et al. 2014).
Literature References
PubMed ID Title Journal Year
24788042 Processing of heparanase is mediated by syndecan-1 cytoplasmic domain and involves syntenin and α-actinin

Shteingauz, A, Ilan, N, Vlodavsky, I

Cell Mol Life Sci 2014
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
clathrin-dependent endocytosis (0072583)
Orthologous Events
proHPSE:SDC1 is delivered to lysosomes (Bos taurus)
proHPSE:SDC1 is delivered to lysosomes (Canis familiaris)
proHPSE:SDC1 is delivered to lysosomes (Drosophila melanogaster)
proHPSE:SDC1 is delivered to lysosomes (Gallus gallus)
proHPSE:SDC1 is delivered to lysosomes (Mus musculus)
proHPSE:SDC1 is delivered to lysosomes (Rattus norvegicus)
proHPSE:SDC1 is delivered to lysosomes (Sus scrofa)
proHPSE:SDC1 is delivered to lysosomes (Xenopus tropicalis)
Authored
D'Eustachio, P  (2022-05-26)
Reviewed
D'Eustachio, P  (2025-05-15)
Created
D'Eustachio, P  (2022-05-26)
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